RESUMO
A 65-year old woman developed progressive, firm, mild to moderately itchy, erythematous, papular and nodular lesions, over cheeks, extensors of limbs, scalp and lower back without any accompanying systemic complaints except for severe backache. Initially clinical diagnosis was cutaneous sarcoidosis. However presence of myeloblasts, monoblasts, myelocytes and metamyelocytes in peripheral blood smear and typical histopathology of nodule with mixed cellular infiltrate more around blood vessels, sweat glands and hair follicles with admixture of larger polymorphonuclears (myeloblasts/myelocytes), eosinophils with double nuclei, and larger phagocytic cells confirmed the diagnosis of acute myelogenous leukemia (AML).
RESUMO
Two cases of Brunsting Perry cicatricial pemphigoid are being reported for their rarity. Initially as a clearcut clinical diagnosis was not possible, both cases were labelled as a typical vesiculo-bullous disorder. Later only after repeated biopsies, dermoepidermal junction split, fibrosis and perivascular mononuclear infiltrate were seen and a diagnosis of cicatricial pemphigoid was established which was further confirmed by immunoflurescent studies. A favourable response to dapsone was observed in both cases.
RESUMO
A case of leukonychia totalis in a 20-year old. healthy man which manifested at the age of 2 years after an episode of acute illness is being reported.