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1.
Artigo em Inglês | MEDLINE | ID: mdl-17642843

RESUMO

28 patients of hereditary punctate palmoplantar keratoderma (HPPK) were selected from DermatoVenereology out patients of Rajindra Hospital, Patiala. Cases were divided into group A with PPK as major feature and group 6 with PPK as minor feature. 11/28 belonged to group A and 17/28 to group B. Group A patients revealed scattered pundate PPK in 6 and scattered pundate plus focal plaques in 5, while in group B patterns seen were KPPC (6), KPPC with focal (6), focal plus scattered punctate (3) and diffuse with superimposed KPPC (2).

2.
Artigo em Inglês | MEDLINE | ID: mdl-17642860

RESUMO

Lichen planus is a common disorder and 40-50% of LP patients also reveal mucosal lesions. It is well known that mucosal LP lesions take very long to heal in comparison to cutaneous lesions. Rarely erosive mucosal LP can turn malignant. Both CMI and humoral immunity may play role in aetiopathogenesis of LP. Present study was conducted to study and compare CMI, Humoral Immunity, histopathology in mucosal and nonmucosal LP.

3.
Artigo em Inglês | MEDLINE | ID: mdl-17656904
4.
Artigo em Inglês | MEDLINE | ID: mdl-17656931

RESUMO

A 25-year-old male had accessory auricles at birth and developed ectopic digit since 1 year. As this association could not be traced in literature, it is being reported. Ectopic digit in the present case was differentiated from supernumerary digit because of late onset at the age of 24 years, recurrence after surgery, unilateral appearance, had origin from central depression of a well defined, round plaque on the distal inter-phalangeal joint of left thumb and had curvature simulating cutaneous horn. X-ray thumb did not reveal any bone formation in this ectopic digit.

5.
Artigo em Inglês | MEDLINE | ID: mdl-17656953

RESUMO

Two cases of dilated pore of Winer were observed. First case had single defined black papule with well defined margin, central pore and discharge of black powdery material from nose since 3 years. The second case had one 9 mm, black well-defined papule with central pore discharging black powdery material on right forearm since 9 months and 9 similar smaller papules were seen on forearm and lower abdomen. Histopathologically both revealed greatly dilated infundibulum lined by acanthotic epidermis and atrophic subinfundibular hair structures thus confirming diagnosis of dilated pore of Winer.

6.
Artigo em Inglês | MEDLINE | ID: mdl-17656955

RESUMO

A 45-years-old woman came with diffuse yellowwaxy thickening, dryness and scaly skin of palms and soles and thickening of knuckles on dorsa of hands since 2 years. In addition, she had hoarseness of voice, weight gain, slow response, intolerance to cold, loss of pubic and axillary hair, generalised dryness and coarseness of skin, and mask like fades. Diagnosis of palmoplantar keratoderma and myxedema was confirmed by investigations.

7.
Artigo em Inglês | MEDLINE | ID: mdl-17664702

RESUMO

Two cases of blue rubber bleb nevus syndrome are being reported because of their rarity. Case one was classical with multiple, soft, painful, tender, bleb- like, bluish nodules and gastro- intestinal tract bleeding. In case 2 typical zosteriform, soft bluish, compressible, tender, painful nodules simulating that of blue rubber bleb nevus syndrome were present on the right thigh since the age of 14 years. He refused biopsy and therefore it was not possible to exclude other segmental vascular naevi.

9.
Artigo em Inglês | MEDLINE | ID: mdl-17664731

RESUMO

Four cases of Leser-Trelat sign were studied in detail clinically and were investigated to establish their association with internal malignancy. One of them had papillary carcinoma of thyroid and the second had carcinoma of the body of pancreas. USG revealed mass in the gall bladder in the third case. He was lost before completion of other investigations. The fourth case was normal. So patients with Leser-Trclat sign must be carefully investigated in detail.

10.
Artigo em Inglês | MEDLINE | ID: mdl-17664734

RESUMO

Fourteen cases of sub acute cutaneous lupus erythematosus (SCLE) were selected from Dermato-Venereology outpatients during the last 2(1/2) years. Clinically all patients revealed photosensitivity and annular plaques either covered with peripheral collarette of scale or EM--like or DLE--like lesions. Systemic associations were arthralgia in 4, hypertension in I. rheumatoid arthritis in I and pulmonary tuberculosis in L Histopathologically epidermal atrophy, interface dermatitis, basal cell degeneration, colloid bodies and mononuclear infiltrate of dermis were salient features. Good response to 15 mg prednisolonc, medium potency topical steroids and sunscreens was seen in all cases.

11.
Artigo em Inglês | MEDLINE | ID: mdl-17664742

RESUMO

A 31-year-old man had asymptomatic, stationary, 1.5X2 cm, shiny, smooth, dark blue nodule on dorsum of right hand since 12-14 years. In addition he had developed extensive eruption of yellow to orange papulonodular lesions on extensors of limbs and buttocks since one and half months. Investigations confirmed that yellow papules were xanthomatosis and he had associated diabetes mellitus and hyperlipidaemia. Biopsy of blue nodule confirmed the clinical diagnosis of cellular blue naevus. Cellular blue naevus is rare and its association with xanthomatosis and diabetes mellitus were interesting features of above patients which is being reported for its rarity.

12.
Artigo em Inglês | MEDLINE | ID: mdl-28615565

RESUMO

One hundred and forty-eight cases of clinically diagnosed seborrhoeic keratoses and 12 of stuccokeratoses were selected from Dermato Venereology department of Rajendra Hospital, Patiala, during a period of 15 months. Histopathology confirmed that 123 out of 148 cases were of seborrhoeic keratosis and 8 out of 12 were of stuccokeratosis. T-lymphocyte counts in histopathologically confirmed cases were done by Thomson's E-rosette method (1977). Peripheral T-lymphocyte counts were statistically significantly increased in both seborrhoeic keratosis and stucco keratosis, thus revealing important role of cell mediated immunity in seborrhoeic keralosis.

13.
Artigo em Inglês | MEDLINE | ID: mdl-28615582
14.
Artigo em Inglês | MEDLINE | ID: mdl-20877048
15.
Artigo em Inglês | MEDLINE | ID: mdl-20877081

RESUMO

Four young males with chronic non pitting swelling of lower legs associated with multiple ulcers, scars and pigmentation after parenteral drug abuse were observed in the Dermatovenereology department during last one year. Three of them had active ulcers which healed with withdrawal of offending drug, use of systemic and topical antibiotics and B-complex. All cases were referred to the deaddiction centre. The characteristic clinical features helped in the diagnosis even before history of drug abuse was obtained.

17.
Artigo em Inglês | MEDLINE | ID: mdl-20877089

RESUMO

The histopathologic features of pityriasis rosea (PR) have been considered by many authors to be compatible with those of dermatitis, but it is not surprising that histological difference may exist between PR and dermatitis. fifty patients of pityriasis rosea were included in this study. We studied the 50 biopsies including 9 biopsies from herald patches. The characteristic features were; absence or decrease of the granular cell layer, extravasation of red blood cells in papillary dermis and partly into the epidermis, dyskeratosis, liquefaction of basal cells, homogenization of papillary collagen, intraepidermal vesicles in apparently dry skin. In addition of these features, we observed prominent delling of epidermis and a typical spongiotic pattern not reported earlier. The biopsies from herald patches showed minor differences from the secondary lesions. We also compared the histopathological features of recent lesions with older lesions.

18.
Artigo em Inglês | MEDLINE | ID: mdl-20877099

RESUMO

A 65-year old woman developed progressive, firm, mild to moderately itchy, erythematous, papular and nodular lesions, over cheeks, extensors of limbs, scalp and lower back without any accompanying systemic complaints except for severe backache. Initially clinical diagnosis was cutaneous sarcoidosis. However presence of myeloblasts, monoblasts, myelocytes and metamyelocytes in peripheral blood smear and typical histopathology of nodule with mixed cellular infiltrate more around blood vessels, sweat glands and hair follicles with admixture of larger polymorphonuclears (myeloblasts/myelocytes), eosinophils with double nuclei, and larger phagocytic cells confirmed the diagnosis of acute myelogenous leukemia (AML).

19.
Artigo em Inglês | MEDLINE | ID: mdl-20877109

RESUMO

Two cases of Brunsting Perry cicatricial pemphigoid are being reported for their rarity. Initially as a clearcut clinical diagnosis was not possible, both cases were labelled as a typical vesiculo-bullous disorder. Later only after repeated biopsies, dermoepidermal junction split, fibrosis and perivascular mononuclear infiltrate were seen and a diagnosis of cicatricial pemphigoid was established which was further confirmed by immunoflurescent studies. A favourable response to dapsone was observed in both cases.

20.
Artigo em Inglês | MEDLINE | ID: mdl-20877113

RESUMO

A case of leukonychia totalis in a 20-year old. healthy man which manifested at the age of 2 years after an episode of acute illness is being reported.

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