RESUMO
The present study was conducted in 50 patients of various subtypes of leprosy (Lepromatous, Tuberculoid, Borderline borderline) and 25 healthy control, for detection of Australia antigen and various liver function tests (serum protein, cholesterol, alkaline phosphates, SGOT, SGPT, bilirubin and liver biopsy) to see incidence of Australia Antigen and derangement in liver function. It was concluded that incidence of Australia antigen in study and control group was zero. Total serum protein and serum globulin was increased in lepromatous leprosy. A/G ratio was reversed in 34.3% and 50% in lepromatous and tuberculoid leprosy respectively. Granulomatous hepatitis was seen in 66.66% and 50% cases of lepromatous and tuberculoid leprosy respectively. No relationships was established between hepatic lesion, Australia antigen and liver function test.
Assuntos
Antígenos de Superfície da Hepatite B/análise , Hanseníase Dimorfa/fisiopatologia , Hanseníase Virchowiana/fisiopatologia , Hanseníase Tuberculoide/fisiopatologia , Fígado/fisiopatologia , Adolescente , Adulto , Feminino , Hepatite Viral Humana/complicações , Humanos , Hanseníase Dimorfa/complicações , Hanseníase Virchowiana/complicações , Hanseníase Tuberculoide/complicações , Fígado/patologia , Testes de Função Hepática , Masculino , Pessoa de Meia-IdadeRESUMO
The prevalence of cutaneous, medical and surgical disorders was studied in 846 leprosy patients. Common cutaneous disorders among leprosy patients were pityriasis versicolor, tinea, pyodermas, warts, acquired ichthyosis, scabies, pediculosis and callosities. Only pityriasis versicolor had higher incidence when compared to general population. Common medical diseases were tuberculosis, infective hepatitis and diabetes mellitus. The epidemiological importance of their co-existence with leprosy is discussed and relevant literature of other diseases found to be frequently associated with leprosy is reviewed.