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1.
Int J STD AIDS ; 28(2): 196-198, 2017 02.
Artigo em Inglês | MEDLINE | ID: mdl-27270897

RESUMO

Immune reconstitution inflammatory syndrome is an inflammatory reaction in HIV-infected patients after initiation of antiretroviral therapy resulting from restored immunity to specific infectious or non-infectious antigens. A 36-year-old male patient on highly active antiretroviral therapy of six months duration, presented with reddish, tender lesions over medial aspect of arm and a single, anaesthetic patch. Tender fluctuant swellings were seen on the medial aspect of left forearm. A few of them had ruptured spontaneously discharging pus. A skin biopsy from the anaesthetic patch showed caseating epitheloid granulomas. A diagnosis of Hansen's disease borderline tuberculoid in type 1 reversal reaction, with formation of nerve abscess due to Immune Reconstitution Inflammatory Syndrome was made. The patient was started on multibacillary multidrug therapy as per WHO guidelines and highly active antiretroviral therapy was continued.


Assuntos
Infecções Oportunistas Relacionadas com a AIDS/induzido quimicamente , Abscesso/tratamento farmacológico , Infecções por HIV/complicações , Hipersensibilidade/etiologia , Síndrome Inflamatória da Reconstituição Imune/complicações , Hanseníase Dimorfa/induzido quimicamente , Hanseníase Tuberculoide/induzido quimicamente , Infecções Oportunistas Relacionadas com a AIDS/tratamento farmacológico , Abscesso/etiologia , Adulto , Terapia Antirretroviral de Alta Atividade/efeitos adversos , Biópsia , Infecções por HIV/tratamento farmacológico , Infecções por HIV/imunologia , Humanos , Hipersensibilidade/diagnóstico , Hansenostáticos/uso terapêutico , Hanseníase Dimorfa/diagnóstico , Hanseníase Tuberculoide/diagnóstico , Masculino , Prednisolona/uso terapêutico , Pele/patologia , Resultado do Tratamento
4.
Indian J Lepr ; 87(3): 169-74, 2015.
Artigo em Inglês | MEDLINE | ID: mdl-26999990

RESUMO

Leprosy has been increasingly known to have an enigmatic relationship with human immunodeficiency virus infection. Co-infection may result in atypical manifestations of leprosy. A 45-year old human immunodeficiency virus-positive male; agricultural laborer presented with a swelling over right elbow, right hand deformity, generalized itching and recurrent vesicles overthe perinasal area. Clinical and investigational findings were consistent with mononeuritic type of Hansen's disease with right sided silent ulnar nerve abscess, partial claw hand. CD4+ count of the patientwas 430 cells/cmm. This patient also hadherpes simplex labialis, with HIV-associated pruritus. To the best of our knowledge such an atypical presentation has not been reported earlier.


Assuntos
Abscesso/etiologia , Infecções por HIV/complicações , Hanseníase Tuberculoide/complicações , Hanseníase Tuberculoide/patologia , Nervo Ulnar/patologia , Anti-Inflamatórios/uso terapêutico , Humanos , Hansenostáticos/uso terapêutico , Hanseníase Tuberculoide/diagnóstico , Hanseníase Tuberculoide/tratamento farmacológico , Masculino , Pessoa de Meia-Idade , Prednisolona/uso terapêutico , Neuropatias Ulnares/diagnóstico , Neuropatias Ulnares/patologia
8.
Bull Soc Pathol Exot ; 98(3): 187-92, 2005 Sep.
Artigo em Francês | MEDLINE | ID: mdl-16267958

RESUMO

Immune reconstitution syndrome (IRIS) is an unusual inflammatory reaction to an opportunistic infection in an HIV-positive patient. This syndrome occurs when immunity is restored in the first months of an effective highly active antiretroviral treatment (HAART). First, we described all patients with a cutaneous form of IRIS. Then, between 1992 and 2004 we conducted a retrospective cohort study comparing Herpes Zoster and Herpes Simplex infections among untreated patients, patients treated by HAART for < or = six months, and patients treated for > six months. We observed three cases of atypical leprosy and three original observations: two of these were fistulisation of lymph node histoplasmosis and tuberculosis, the third one reports the recurrence of a treated cutaneous leishmaniasis. Multivariate analysis showed that, after controlling for age, sex and CD4 counts, patients receiving HAART for < or = six months were more likely to develop Herpes Zoster or herpes simplex infections (p < 0.005). Herpes Simplex and Herpes Zoster infections are the two most frequent dermatological manifestations in our tropical setting. Although mycobacterial infections are more rarely observed than in visceral IRIS, the increased incidence of leprosy may be quite significant when the availability of HAART spreads to developing countries.


Assuntos
Terapia Antirretroviral de Alta Atividade , Dermatite/etiologia , Infecções por HIV/tratamento farmacológico , Hanseníase/complicações , Dermatopatias Infecciosas/etiologia , Abscesso/etiologia , Adulto , Estudos de Coortes , Fístula Cutânea/etiologia , Dermatite/imunologia , Suscetibilidade a Doenças , Feminino , Fístula/etiologia , Guiana Francesa/epidemiologia , Infecções por HIV/complicações , Herpes Simples/etiologia , Herpes Simples/imunologia , Herpes Zoster/etiologia , Herpes Zoster/imunologia , Histoplasmose/complicações , Histoplasmose/imunologia , Humanos , Hospedeiro Imunocomprometido , Memória Imunológica , Leishmaniose Cutânea/complicações , Leishmaniose Cutânea/imunologia , Hanseníase/imunologia , Doenças Linfáticas/etiologia , Masculino , Pessoa de Meia-Idade , Recidiva , Estudos Retrospectivos , Dermatopatias Infecciosas/imunologia , Tuberculose dos Linfonodos/complicações , Tuberculose dos Linfonodos/imunologia
12.
Lepr Rev ; 68(4): 333-5, 1997 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-9503870

RESUMO

An old borderline-lepromatous leprosy patient, treated initially with DDS monotherapy followed by MDT, 11 years later during surveillance presented with 3-month-old asymptomatic cystic swelling, arising from the right ulnar nerve without exhibiting any evidence to document relapse of the disease. It responded promptly to corticosteroid therapy. This unusual clinical presentations of ulnar nerve abscess has not been reported elsewhere.


Assuntos
Abscesso/etiologia , Hanseníase Dimorfa/complicações , Hanseníase Virchowiana/complicações , Doenças do Sistema Nervoso Periférico/etiologia , Nervo Ulnar , Abscesso/tratamento farmacológico , Abscesso/microbiologia , Adulto , Anti-Inflamatórios/uso terapêutico , Feminino , Seguimentos , Humanos , Metilprednisolona/uso terapêutico , Doenças do Sistema Nervoso Periférico/tratamento farmacológico , Recidiva
13.
Lepr Rev ; 67(3): 217-21, 1996 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-8885616

RESUMO

We report two cases of nerve abscesses, one suffering from lepromatous leprosy (LL) and the other from tuberculoid neural leprosy. Neither had any signs of reactions. Both were untreated cases. Surgical nerve decompression and systemic prednisolone had resolved the nerve abscess in the first case, whereas the second one responded only to surgical nerve decompression. The unusual nature of clinical presentation of nerve abscess has been outlined.


Assuntos
Abscesso , Articulação do Cotovelo/patologia , Antebraço/patologia , Doenças do Sistema Nervoso Periférico/etiologia , Abscesso/etiologia , Abscesso/cirurgia , Adulto , Articulação do Cotovelo/cirurgia , Antebraço/cirurgia , Humanos , Hanseníase Virchowiana/complicações , Hanseníase Tuberculoide/complicações , Masculino , Doenças do Sistema Nervoso Periférico/fisiopatologia , Doenças do Sistema Nervoso Periférico/cirurgia
16.
Clin Exp Dermatol ; 15(5): 349-51, 1990 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-2171820

RESUMO

Two leprosy patients with neuritis caused by giant abscesses involving almost the entire ulnar nerve are described. One patient, who also had skin lesions, was diagnosed histopathologically as having borderline tuberculoid leprosy both on skin and nerve biopsy, and the other, with only nerve involvement, belonged to the pure neuritic group. The lepromin test was strongly positive (with a vesicular reaction in one patient) and lymphocyte transformation to Mycobacterium leprae antigen was raised. These lesions can be easily mistaken for a peripheral nerve tumour in places where leprosy is uncommon. A brief account of the management of nerve abscess in leprosy is given.


Assuntos
Abscesso/patologia , Hanseníase Tuberculoide/complicações , Nervo Ulnar/patologia , Abscesso/etiologia , Adulto , Criança , Humanos , Masculino , Doenças do Sistema Nervoso Periférico/etiologia , Doenças do Sistema Nervoso Periférico/patologia
18.
Indian J Lepr ; 59(4): 469-71, 1987.
Artigo em Inglês | MEDLINE | ID: mdl-3451928

RESUMO

Unusual presentation of a BT leprosy patient with multiple nerve abscess and an approach to diagnosis and management of the problem have been described. The article will refamiliarize the reader with unusual nature of presentation, diagnosis and management of nerve abscess associated with leprosy.


Assuntos
Abscesso/etiologia , Hanseníase/complicações , Neurite (Inflamação)/etiologia , Adulto , Braço , Humanos , Hanseníase/diagnóstico , Masculino , Úlcera Cutânea/etiologia
20.
Arq. bras. neurocir ; 6(3): 147-55, set. 1987. ilus, tab
Artigo em Português | LILACS | ID: lil-73080

RESUMO

Vinte abscessos de nervos periféricos foram observados en 19 pacientes hansenianos, dos quais 16 tinham a forma tuberculóide e 3 a variedade dimorfa da doença. Säo feitas consideraçöes acerca da formaçäo destes abscessos, sua sintomatologia, as indicaçöes do tratamento cirúrgico, o tipo de cirurgia realizada, bem como o resultado pós-operatório


Assuntos
Criança , Adolescente , Adulto , Pessoa de Meia-Idade , Humanos , Masculino , Feminino , Abscesso/cirurgia , Hanseníase/complicações , Nervos Periféricos , Abscesso/etiologia , Doenças do Sistema Nervoso Periférico/etiologia
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