Immunohistological analysis of in situ expression of mycobacterial antigens in skin lesions of leprosy patients across the histopathological spectrum. Association of Mycobacterial lipoarabinomannan (LAM) and Mycobacterium leprae phenolic glycolipid-I (PGL-I) with leprosy reactions.

Verhagen, C; Faber, W; Klatser, P; Buffing, A; Naafs, B; Das, P

Verhagen, C; Faber, W; Klatser, P; Buffing, A; Naafs, B; Das, P.

Affiliation

Verhagen C; Departments of Dermatology, Academic Medical Center, University of Amsterdam, The Netherlands.

Am J Pathol ; 154(6): 1793-804, 1999 Jun.

Article in En | MEDLINE | ID: mdl-10362804

Subject(s)

Antigens, Bacterial/biosynthesis; Bacterial Proteins; Leprosy/microbiology; Skin Diseases/microbiology; Antibodies, Bacterial/blood; Antibodies, Monoclonal; Antibody Specificity; Antigens, Bacterial/immunology; Chaperonin 60; Chaperonins/biosynthesis; Chaperonins/immunology; Glycolipids/biosynthesis; Glycolipids/immunology; Humans; Immunohistochemistry; Leprosy/immunology; Leprosy/metabolism; Lipopolysaccharides/biosynthesis; Lipopolysaccharides/immunology; Macrophages/metabolism; Mycobacterium leprae/genetics; Mycobacterium leprae/immunology; Mycobacterium leprae/isolation & purification; Predictive Value of Tests; Retrospective Studies; Skin Diseases/immunology; Skin Diseases/metabolism

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Full text: 1 Theme: Complicacoes / Geral / Prevencao_controle / Tratamento_medicamentoso Database: MEDLINE Main subject: Skin Diseases / Bacterial Proteins / Leprosy / Antigens, Bacterial Type of study: Observational_studies / Risk_factors_studies / Screening_studies Language: En Journal: Am J Pathol Year: 1999 Document type: Article

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