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Genetic diversity of Mycobacterium leprae in the state of São Paulo, an area of low-leprosy incidence in Brazil
Finardi, Amanda Juliane; Oliveira, Nathan Guilherme de; Moraes, Eloise Brasil de; Batista, Lavínia Cássia Ferreira; Bortolomai, Bruna Eduarda; Suffys, Philip Noel; Baptista, Ida Maria Foschiani Dias.
Afiliación
  • Finardi, Amanda Juliane; Instituto Lauro de Souza Lima. Bauru. BR
  • Oliveira, Nathan Guilherme de; Instituto Lauro de Souza Lima. Bauru. BR
  • Moraes, Eloise Brasil de; Instituto Lauro de Souza Lima. Bauru. BR
  • Batista, Lavínia Cássia Ferreira; Instituto Lauro de Souza Lima. Bauru. BR
  • Bortolomai, Bruna Eduarda; Instituto Lauro de Souza Lima. Bauru. BR
  • Suffys, Philip Noel; Fundação Oswaldo Cruz. Laboratório de Biologia Molecular Aplicada a Micobactérias. Rio de Janeiro. BR
  • Baptista, Ida Maria Foschiani Dias; Instituto Lauro de Souza Lima. Bauru. BR
Rev. Soc. Bras. Med. Trop ; 56: e0612, 2023. graf
Article en En | LILACS-Express | LILACS, SES-SP, SESSP-ILSLPROD, SES-SP, SESSP-ILSLACERVO, SES-SP | ID: biblio-1431402
Biblioteca responsable: BR1.1
Ubicación: BR191.1; 9852/S
ABSTRACT
ABSTRACT

Background:

Brazil has the second largest number of leprosy cases worldwide, and the state of São Paulo has been considered non-endemic since 2006.

Methods:

We analyzed 16 variable number tandem repeats loci and three single nucleotide polymorphisms loci of Mycobacterium leprae (M. leprae) in 125 clinical isolates from patients in different municipalities in the state.

Results:

The clustering pattern of M. leprae indicated that the transmission of leprosy persisted in the state and included scenarios of intra-extra-familial transmission in areas with low endemicity.

Conclusions:

A significantly active circulation of M. leprae was observed. Therefore, surveillance and control measures must be implemented.
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Texto completo: 1 Tema: Epidemiologia / Geral / Transmissao Bases de datos: LILACS / SES-SP Tipo de estudio: Incidence_studies / Risk_factors_studies País/Región como asunto: America do sul / Brasil Idioma: En Revista: Rev. Soc. Bras. Med. Trop Año: 2023 Tipo del documento: Article
Texto completo
Imprimir
XML
Buscar en Google

Texto completo: 1 Tema: Epidemiologia / Geral / Transmissao Bases de datos: LILACS / SES-SP Tipo de estudio: Incidence_studies / Risk_factors_studies País/Región como asunto: America do sul / Brasil Idioma: En Revista: Rev. Soc. Bras. Med. Trop Año: 2023 Tipo del documento: Article