[Study of T lymphocyte subpopulations in patients with leprosy, using incubation with theophylline]. / Estudio de subpoblaciones de linfocitos T en pacientes con lepra, mediante la incubación con teofilina.
Med Cutan Ibero Lat Am
; 16(5): 397-401, 1988.
Article
en Es
| MEDLINE
| ID: mdl-3070196
ABSTRACT
T cells and the theophylline resistant cells (the-r, helper cells) in peripheral blood of patients with different forms of leprosy were studied. Active lepromatous patients (LL+) showed a significant decrease in T lymphocytes and the-r cells. Nevertheless, in LL+ developing a reactional episode of erythema nodosum (LL-ENL) a restoration in the level of the-r cells was observed. It is concluded that in LL+ patients the depression of T cells and the-r cells represents an imbalance in the T-T cellular cooperation with a defective cellular immune response. On the other hand, the recovery of the-r cells in LL-ENL support the hypothesis of a cell mediated immune mechanism in the immunopathology of this reactional episode.
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Tema:
Complicacoes
/
Geral
/
Tratamento_medicamentoso
Bases de datos:
MEDLINE
Asunto principal:
Teofilina
/
Linfocitos T
/
Lepra
Idioma:
Es
Revista:
Med Cutan Ibero Lat Am
Año:
1988
Tipo del documento:
Article