The early diagnosis of leprosy: the first clinical findings observed in segregated children of leprous parents

ABSTRACT

A discussion is presented of the desirability of the early diagnosis of leprosy, in which (a) it is pointed out that the incidence and commmunicability of the disease have not been determined, and (b) it is suggested that the knowledge of its epidemiology, pathogenesis and treatment may be advanced by the recognition and study of its earlier phases. The clinical findings of early cases are outlined, and emphasis is placed on the fact that in the early stages of the disease there may be only minor neurological findings, and that the skin lesions which may or may not be evident in these stages are often of short duration and cannot be regarded as specific to leprosy. One hundred and eight children born of leprous parents, and subsequently maintained in an institution segregated from contact with leprous persons, were observed for a period of three years. Ten of these children have developed leprosy. The first clinical findings noted and the subsequent evolution of the disease are indicated, and are exemplified by notes of three cases.