Search | Virtual Health Library

1.

Serum biomarker levels predict disability progression in patients with primary progressive multiple sclerosis.

Fissolo, Nicolás; Benkert, Pascal; Sastre-Garriga, Jaume; Mongay-Ochoa, Neus; Vilaseca-Jolonch, Andreu; Llufriu, Sara; Blanco, Yolanda; Hegen, Harald; Berek, Klaus; Perez-Miralles, Francisco; Rejdak, Konrad; Villar, Luisa M; Monreal, Enric; Alvarez-Lafuente, Roberto; Soylu, Onder K; Abdelhak, Ahmed; Bachhuber, Franziska; Tumani, Hayrettin; Martínez-Yélamos, Sergio; Sánchez-López, Antonio J; García-Merino, Antonio; Gutiérrez, Lucía; Castillo-Trivino, Tamara; Lycke, Jan; Rosenstein, Igal; Furlan, Roberto; Filippi, Massimo; Téllez, Nieves; Ramió-Torrentà, Lluís; Lünemann, Jan D; Wiendl, Heinz; Eichau, Sara; Khalil, Michael; Kuhle, Jens; Montalban, Xavier; Comabella, Manuel.

J Neurol Neurosurg Psychiatry ; 95(5): 410-418, 2024 Apr 12.

Article in English | MEDLINE | ID: mdl-37940409

2.

Short-chain fatty acids during pregnancy in multiple sclerosis: A prospective cohort study.

Cuello, Juan Pablo; Martínez Ginés, María Luisa; García Domínguez, José Manuel; Tejeda-Velarde, Amalia; Lozano Ros, Alberto; Higueras, Yolanda; Meldaña Rivera, Ariana; Goicochea Briceño, Haydee; Garcia-Tizon, Santiago; de León-Luis, Juan; Medina Heras, Silvia; Fernández Velasco, José Ignacio; Pérez-Pérez, Silvia; García-Martínez, María Ángel; Pardo-Rodríguez, Beatriz; Domínguez-Mozo, María Inmaculada; García-Calvo, Estefanía; Estévez, Héctor; Luque-García, Jose Luis; Villar, Luisa Maria; Alvarez-Lafuente, Roberto.

Eur J Neurol ; 29(3): 895-900, 2022 03.

Article in English | MEDLINE | ID: mdl-34662474

3.

Syncytin-1/HERV-W envelope is an early activation marker of leukocytes and is upregulated in multiple sclerosis patients.

Garcia-Montojo, Marta; Rodriguez-Martin, Eulalia; Ramos-Mozo, Priscila; Ortega-Madueño, Isabel; Dominguez-Mozo, Maria Inmaculada; Arias-Leal, Ana; García-Martínez, Maria Ángel; Casanova, Ignacio; Galan, Victoria; Arroyo, Rafael; Álvarez-Lafuente, Roberto; Villar, Luisa María.

Eur J Immunol ; 50(5): 685-694, 2020 05.

Article in English | MEDLINE | ID: mdl-32012247

4.

Neurofilament light chain and oligoclonal bands are prognostic biomarkers in radiologically isolated syndrome.

Matute-Blanch, Clara; Villar, Luisa M; Álvarez-Cermeño, José C; Rejdak, Konrad; Evdoshenko, Evgeniy; Makshakov, Gleb; Nazarov, Vladimir; Lapin, Sergey; Midaglia, Luciana; Vidal-Jordana, Angela; Drulovic, Jelena; García-Merino, Antonio; Sánchez-López, Antonio J; Havrdova, Eva; Saiz, Albert; Llufriu, Sara; Alvarez-Lafuente, Roberto; Schroeder, Ina; Zettl, Uwe K; Galimberti, Daniela; Ramió-Torrentà, Lluís; Robles, René; Quintana, Ester; Hegen, Harald; Deisenhammer, Florian; Río, Jordi; Tintoré, Mar; Sánchez, Alex; Montalban, Xavier; Comabella, Manuel.

Brain ; 141(4): 1085-1093, 2018 04 01.

Article in English | MEDLINE | ID: mdl-29452342

5.

Multimarker risk stratification approach at multiple sclerosis onset.

Fernández-Paredes, Lidia; Casrouge, Armanda; Decalf, Jérémie; de Andrés, Clara; Villar, Luisa Maria; Pérez de Diego, Rebeca; Alonso, Bárbara; Álvarez Cermeño, José Carlos; Arroyo, Rafael; Tejera-Alhambra, Marta; Navarro, Joaquín; Oreja-Guevara, Celia; López Trascasa, Margarita; Seyfferth, Ansgar; García Martínez, Maria Angel; Álvarez Lafuente, Roberto; Albert, Matthew L; Sánchez-Ramón, Silvia.

Clin Immunol ; 181: 43-50, 2017 08.

Article in English | MEDLINE | ID: mdl-28578025

6.

Study of the anti-JCV antibody levels in a Spanish multiple sclerosis cohort.

Dominguez-Mozo, María I; Rus, Macarena; Santiago, Jose L; Izquierdo, Guillermo; Casanova, Ignacio; Galan, Victoria; Garcia-Martinez, M Angel; Arias-Leal, Ana M; García-Montojo, Marta; Pérez-Pérez, Silvia; Arroyo, Rafael; Alvarez-Lafuente, Roberto.

Eur J Clin Invest ; 47(2): 158-166, 2017 Feb.

Article in English | MEDLINE | ID: mdl-28036121

7.

Lipid-specific immunoglobulin M bands in cerebrospinal fluid are associated with a reduced risk of developing progressive multifocal leukoencephalopathy during treatment with natalizumab.

Villar, Luisa M; Costa-Frossard, Lucienne; Masterman, Thomas; Fernandez, Oscar; Montalban, Xavier; Casanova, Bonaventura; Izquierdo, Guillermo; Coret, Francisco; Tumani, Hayrettin; Saiz, Albert; Arroyo, Rafael; Fink, Katharina; Leyva, Laura; Espejo, Carmen; Simó-Castelló, María; García-Sánchez, María I; Lauda, Florian; Llufriú, Sara; Álvarez-Lafuente, Roberto; Olascoaga, Javier; Prada, Alvaro; Oterino, Agustín; de Andrés, Clara; Tintoré, Mar; Ramió-Torrentà, Lluis; Rodríguez-Martín, Eulalia; Picón, Carmen; Comabella, Manuel; Quintana, Ester; Agüera, Eduardo; Díaz, Santiago; Fernandez-Bolaños, Ricardo; García-Merino, Juan A; Landete, Lamberto; Menéndez-González, Manuel; Navarro, Laura; Pérez, Domingo; Sánchez-López, Fernando; Serrano-Castro, Pedro J; Tuñón, Alberto; Espiño, Mercedes; Muriel, Alfonso; Bar-Or, Amit; Álvarez-Cermeño, José C.

Ann Neurol ; 77(3): 447-57, 2015 Mar.

Article in English | MEDLINE | ID: mdl-25581547

8.

Adaptive natural killer cell response to cytomegalovirus and disability progression in multiple sclerosis.

Martínez-Rodríguez, Jose E; Cobo-Calvo, Alvaro; Villar, Luisa M; Munteis, Elvira; Blanco, Yolanda; Rasal, Raquel; Vera, Andrea; Muntasell, Aura; Alvarez-Lafuente, Roberto; Saiz, Albert; Alvarez-Cermeño, Jose C; Martínez-Yélamos, Sergio; Roquer, Jaume; López-Botet, Miguel.

Mult Scler ; 22(6): 741-52, 2016 05.

Article in English | MEDLINE | ID: mdl-26362897

9.

Immunoglobulin M oligoclonal bands: biomarker of targetable inflammation in primary progressive multiple sclerosis.

Villar, Luisa M; Casanova, Bonaventura; Ouamara, Nadia; Comabella, Manuel; Jalili, Farzaneh; Leppert, David; de Andrés, Clara; Izquierdo, Guillermo; Arroyo, Rafael; Avsar, Timuçin; Lapin, Sergey V; Johnson, Trina; Montalbán, Xavier; Fernández, Oscar; Álvarez-Lafuente, Roberto; Masterman, Donna; García-Sánchez, María I; Coret, Francisco; Siva, Aksel; Evdoshenko, Evgeniy; Álvarez-Cermeño, José C; Bar-Or, Amit.

Ann Neurol ; 76(2): 231-40, 2014 Aug.

Article in English | MEDLINE | ID: mdl-24909126

10.

HLA alleles as biomarkers of high-titre neutralising antibodies to interferon-ß therapy in multiple sclerosis.

Núñez, Concepción; Cénit, M Carmen; Alvarez-Lafuente, Roberto; Río, Jordi; Fernández-Arquero, Miguel; Arroyo, Rafael; Montalbán, Xavier; Fernández, Oscar; Oliver-Martos, Begoña; Leyva, Laura; Comabella, Manuel; Urcelay, Elena.

J Med Genet ; 51(6): 395-400, 2014 Jun.

Article in English | MEDLINE | ID: mdl-24748646

11.

HERV-W polymorphism in chromosome X is associated with multiple sclerosis risk and with differential expression of MSRV.

García-Montojo, Marta; de la Hera, Belén; Varadé, Jezabel; de la Encarnación, Ana; Camacho, Iris; Domínguez-Mozo, María; Árias-Leal, Ana; García-Martínez, Angel; Casanova, Ignacio; Izquierdo, Guillermo; Lucas, Miguel; Fedetz, Maria; Alcina, Antonio; Arroyo, Rafael; Matesanz, Fuencisla; Urcelay, Elena; Alvarez-Lafuente, Roberto.

Retrovirology ; 11: 2, 2014 Jan 09.

Article in English | MEDLINE | ID: mdl-24405691

12.

Classification of HHV-6A and HHV-6B as distinct viruses.

Ablashi, Dharam; Agut, Henri; Alvarez-Lafuente, Roberto; Clark, Duncan A; Dewhurst, Stephen; DiLuca, Dario; Flamand, Louis; Frenkel, Niza; Gallo, Robert; Gompels, Ursula A; Höllsberg, Per; Jacobson, Steven; Luppi, Mario; Lusso, Paolo; Malnati, Mauro; Medveczky, Peter; Mori, Yasuko; Pellett, Philip E; Pritchett, Joshua C; Yamanishi, Koichi; Yoshikawa, Tetsushi.

Arch Virol ; 159(5): 863-70, 2014 May.

Article in English | MEDLINE | ID: mdl-24193951

13.

Alternative splicing and proteolytic rupture contribute to the generation of soluble IL-6 receptors (sIL-6R) in rheumatoid arthritis.

Lamas, José Ramón; Rodríguez-Rodríguez, Luis; Tornero-Esteban, Pilar; Villafuertes, Esther; Hoyas, José; Abasolo, Lydia; Varadé, Jezabel; Alvarez-Lafuente, Roberto; Urcelay, Elena; Fernández-Gutiérrez, Benjamín.

Cytokine ; 61(3): 720-3, 2013 Mar.

Article in English | MEDLINE | ID: mdl-23375120

14.

MicroRNAs Associated with Disability Progression and Clinical Activity in Multiple Sclerosis Patients Treated with Glatiramer Acetate.

Casanova, Ignacio; Domínguez-Mozo, María I; De Torres, Laura; Aladro-Benito, Yolanda; García-Martínez, Ángel; Gómez, Patricia; Abellán, Sara; De Antonio, Esther; Álvarez-Lafuente, Roberto.

Biomedicines ; 11(10)2023 Oct 12.

Article in English | MEDLINE | ID: mdl-37893133

15.

Teriflunomide and Epstein-Barr virus in a Spanish multiple sclerosis cohort: in vivo antiviral activity and clinical response.

Domínguez-Mozo, María Inmaculada; González-Suárez, Inés; Villar, Luisa María; Costa-Frossard, Lucienne; Villarrubia, Noelia; Aladro, Yolanda; Pilo, Belén; Montalbán, Xavier; Comabella, Manuel; Casanova-Peño, Ignacio; Martínez-Ginés, María Luisa; García-Domínguez, Jose Manuel; García-Martínez, María Ángel; Arroyo, Rafael; Álvarez-Lafuente, Roberto.

Front Immunol ; 14: 1248182, 2023.

Article in English | MEDLINE | ID: mdl-37841253

16.

Association of Serum Neurofilament Light Chain Levels at Disease Onset With Disability Worsening in Patients With a First Demyelinating Multiple Sclerosis Event Not Treated With High-Efficacy Drugs.

Monreal, Enric; Fernández-Velasco, José Ignacio; García-Sánchez, María Isabel; Sainz de la Maza, Susana; Llufriu, Sara; Álvarez-Lafuente, Roberto; Casanova, Bonaventura; Comabella, Manuel; Ramió-Torrentà, Lluís; Martínez-Rodríguez, José Enrique; Brieva, Luis; Saiz, Albert; Eichau, Sara; Cabrera-Maqueda, José María; Villarrubia, Noelia; Espiño, Mercedes; Pérez-Miralles, Francisco; Montalbán, Xavier; Tintoré, Mar; Quiroga-Varela, Ana; Domínguez-Mozo, María Inmaculada; Rodríguez-Jorge, Fernando; Chico-García, Juan Luís; Lourido, Daniel; Álvarez-Cermeño, José Carlos; Masjuan, Jaime; Costa-Frossard, Lucienne; Villar, Luisa María.

JAMA Neurol ; 80(4): 397-403, 2023 04 01.

Article in English | MEDLINE | ID: mdl-36848127

17.

MHC2TA mRNA levels and human herpesvirus 6 in multiple sclerosis patients treated with interferon beta along two-year follow-up.

Dominguez-Mozo, Maria Inmaculada; Garcia-Montojo, Marta; De Las Heras, Virginia; Garcia-Martinez, Angel; Arias-Leal, Ana Maria; Casanova, Ignacio; Arroyo, Rafael; Alvarez-Lafuente, Roberto.

BMC Neurol ; 12: 107, 2012 Sep 25.

Article in English | MEDLINE | ID: mdl-23009575

18.

Epstein-Barr Virus Load Correlates with Multiple Sclerosis-Associated Retrovirus Envelope Expression.

Pérez-Pérez, Silvia; Domínguez-Mozo, María Inmaculada; García-Martínez, María Ángel; Ballester-González, Rubén; Nieto-Gañán, Israel; Arroyo, Rafael; Alvarez-Lafuente, Roberto.

Biomedicines ; 10(2)2022 Feb 05.

Article in English | MEDLINE | ID: mdl-35203596

19.

Serum levels of IgM to phosphatidylcholine predict the response of multiple sclerosis patients to natalizumab or IFN-ß.

Muñoz, Úrsula; Sebal, Cristina; Escudero, Esther; Urcelay, Elena; Arroyo, Rafael; García-Martínez, Maria A; Quintana, Francisco J; Álvarez-Lafuente, Roberto; Sádaba, Maria Cruz.

Sci Rep ; 12(1): 13357, 2022 08 03.

Article in English | MEDLINE | ID: mdl-35922641

20.

Epstein-Barr Virus and multiple sclerosis in a Spanish cohort: A two-years longitudinal study.

Domínguez-Mozo, María Inmaculada; López-Lozano, Lorena; Pérez-Pérez, Silvia; García-Martínez, Ángel; Torrejón, María José; Arroyo, Rafael; Álvarez-Lafuente, Roberto.

Front Immunol ; 13: 991662, 2022.

Article in English | MEDLINE | ID: mdl-36189297

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