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1.
Soluble adenylyl cyclase inhibition prevents human sperm functions essential for fertilization.
Mol Hum Reprod
; 27(9)2021 09 01.
Article
in English
| MEDLINE | ID: mdl-34463764
2.
Metabolic changes in mouse sperm during capacitation.
Biol Reprod
; 103(4): 791-801, 2020 10 05.
Article
in English
| MEDLINE | ID: mdl-32614044
3.
Optimization of lead compounds into on-demand, nonhormonal contraceptives: leveraging a public-private drug discovery institute collaboration.
Biol Reprod
; 103(2): 176-182, 2020 08 04.
Article
in English
| MEDLINE | ID: mdl-32307523
4.
Capacitation increases glucose consumption in murine sperm.
Mol Reprod Dev
; 87(10): 1037-1047, 2020 10.
Article
in English
| MEDLINE | ID: mdl-32914502
5.
Intracellular activation of ovastacin mediates pre-fertilization hardening of the zona pellucida.
Mol Hum Reprod
; 23(9): 607-616, 2017 09 01.
Article
in English
| MEDLINE | ID: mdl-28911209
6.
Direct action of endocrine disrupting chemicals on human sperm.
EMBO Rep
; 15(7): 758-65, 2014 Jul.
Article
in English
| MEDLINE | ID: mdl-24820036
7.
In vivo characterization of sAC null sperm.
Front Cell Dev Biol
; 11: 1134051, 2023.
Article
in English
| MEDLINE | ID: mdl-37152282
8.
Capacitation induces changes in metabolic pathways supporting motility of epididymal and ejaculated sperm.
Front Cell Dev Biol
; 11: 1160154, 2023.
Article
in English
| MEDLINE | ID: mdl-37440924
9.
On-demand male contraception via acute inhibition of soluble adenylyl cyclase.
Nat Commun
; 14(1): 637, 2023 02 14.
Article
in English
| MEDLINE | ID: mdl-36788210
10.
Mouse sperm energy restriction and recovery (SER) revealed novel metabolic pathways.
Front Cell Dev Biol
; 11: 1234221, 2023.
Article
in English
| MEDLINE | ID: mdl-37655160
11.
Design, Synthesis, and Pharmacological Evaluation of Second-Generation Soluble Adenylyl Cyclase (sAC, ADCY10) Inhibitors with Slow Dissociation Rates.
J Med Chem
; 65(22): 15208-15226, 2022 11 24.
Article
in English
| MEDLINE | ID: mdl-36346696
12.
Discovery of TDI-10229: A Potent and Orally Bioavailable Inhibitor of Soluble Adenylyl Cyclase (sAC, ADCY10).
ACS Med Chem Lett
; 12(8): 1283-1287, 2021 Aug 12.
Article
in English
| MEDLINE | ID: mdl-34413957
13.
Using an Extracellular Flux Analyzer to Measure Changes in Glycolysis and Oxidative Phosphorylation during Mouse Sperm Capacitation.
J Vis Exp
; (155)2020 01 22.
Article
in English
| MEDLINE | ID: mdl-32065141
14.
Molecular Mechanism Underlying the Action of Zona-pellucida Glycoproteins on Mouse Sperm.
Front Cell Dev Biol
; 8: 572735, 2020.
Article
in English
| MEDLINE | ID: mdl-32984353
15.
Shedding light on the role of cAMP in mammalian sperm physiology.
Mol Cell Endocrinol
; 468: 111-120, 2018 06 15.
Article
in English
| MEDLINE | ID: mdl-29146556
16.
A novel cross-species inhibitor to study the function of CatSper Ca2+ channels in sperm.
Br J Pharmacol
; 175(15): 3144-3161, 2018 08.
Article
in English
| MEDLINE | ID: mdl-29723408
17.
A novel biosensor to study cAMP dynamics in cilia and flagella.
Elife
; 52016 Mar 22.
Article
in English
| MEDLINE | ID: mdl-27003291
18.
Targeted inactivation of the mouse epididymal beta-defensin 41 alters sperm flagellar beat pattern and zona pellucida binding.
Mol Cell Endocrinol
; 427: 143-54, 2016 May 15.
Article
in English
| MEDLINE | ID: mdl-26987518
19.
Re-visiting the Protamine-2 locus: deletion, but not haploinsufficiency, renders male mice infertile.
Sci Rep
; 6: 36764, 2016 11 11.
Article
in English
| MEDLINE | ID: mdl-27833122
20.
Controlling fertilization and cAMP signaling in sperm by optogenetics.
Elife
; 42015 Jan 20.
Article
in English
| MEDLINE | ID: mdl-25601414
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