Search | Virtual Health Library

1.

Aging disrupts circadian gene regulation and function in macrophages.

Blacher, Eran; Tsai, Connie; Litichevskiy, Lev; Shipony, Zohar; Iweka, Chinyere Agbaegbu; Schneider, Kai Markus; Chuluun, Bayarsaikhan; Heller, H Craig; Menon, Vilas; Thaiss, Christoph A; Andreasson, Katrin I.

Nat Immunol ; 23(2): 229-236, 2022 02.

Article in English | MEDLINE | ID: mdl-34949832

2.

Our Gut Microbiome: The Evolving Inner Self.

Kundu, Parag; Blacher, Eran; Elinav, Eran; Pettersson, Sven.

Cell ; 171(7): 1481-1493, 2017 Dec 14.

Article in English | MEDLINE | ID: mdl-29245010

3.

Potential roles of gut microbiome and metabolites in modulating ALS in mice.

Blacher, Eran; Bashiardes, Stavros; Shapiro, Hagit; Rothschild, Daphna; Mor, Uria; Dori-Bachash, Mally; Kleimeyer, Christian; Moresi, Claudia; Harnik, Yotam; Zur, Maya; Zabari, Michal; Brik, Rotem Ben-Zeev; Kviatcovsky, Denise; Zmora, Niv; Cohen, Yotam; Bar, Noam; Levi, Izhak; Amar, Nira; Mehlman, Tevie; Brandis, Alexander; Biton, Inbal; Kuperman, Yael; Tsoory, Michael; Alfahel, Leenor; Harmelin, Alon; Schwartz, Michal; Israelson, Adrian; Arike, Liisa; Johansson, Malin E V; Hansson, Gunnar C; Gotkine, Marc; Segal, Eran; Elinav, Eran.

Nature ; 572(7770): 474-480, 2019 08.

Article in English | MEDLINE | ID: mdl-31330533

4.

Myeloid deficiency of the intrinsic clock protein BMAL1 accelerates cognitive aging by disrupting microglial synaptic pruning.

Iweka, Chinyere Agbaegbu; Seigneur, Erica; Hernandez, Amira Latif; Paredes, Sur Herrera; Cabrera, Mica; Blacher, Eran; Pasternak, Connie Tsai; Longo, Frank M; de Lecea, Luis; Andreasson, Katrin I.

J Neuroinflammation ; 20(1): 48, 2023 Feb 24.

Article in English | MEDLINE | ID: mdl-36829230

5.

CD38 in cancer-associated fibroblasts promotes pro-tumoral activity.

Ben Baruch, Bar; Mantsur, Einav; Franco-Barraza, Janusz; Blacher, Eran; Cukierman, Edna; Stein, Reuven.

Lab Invest ; 100(12): 1517-1531, 2020 12.

Article in English | MEDLINE | ID: mdl-32612286

6.

Microbiome-Modulated Metabolites at the Interface of Host Immunity.

Blacher, Eran; Levy, Maayan; Tatirovsky, Evgeny; Elinav, Eran.

J Immunol ; 198(2): 572-580, 2017 01 15.

Article in English | MEDLINE | ID: mdl-28069752

7.

The gut microbiome and hypertension.

Pevsner-Fischer, Meirav; Blacher, Eran; Tatirovsky, Evgeny; Ben-Dov, Iddo Z; Elinav, Eran.

Curr Opin Nephrol Hypertens ; 26(1): 1-8, 2017 01.

Article in English | MEDLINE | ID: mdl-27798455

8.

Alzheimer's disease pathology is attenuated in a CD38-deficient mouse model.

Blacher, Eran; Dadali, Tulin; Bespalko, Alina; Haupenthal, Viola J; Grimm, Marcus O W; Hartmann, Tobias; Lund, Frances E; Stein, Reuven; Levy, Ayelet.

Ann Neurol ; 78(1): 88-103, 2015 Jul.

Article in English | MEDLINE | ID: mdl-25893674

9.

Inhibition of glioma progression by a newly discovered CD38 inhibitor.

Blacher, Eran; Ben Baruch, Bar; Levy, Ayelet; Geva, Nurit; Green, Keith D; Garneau-Tsodikova, Sylvie; Fridman, Micha; Stein, Reuven.

Int J Cancer ; 136(6): 1422-33, 2015 Mar 15.

Article in English | MEDLINE | ID: mdl-25053177

10.

TREM1 disrupts myeloid bioenergetics and cognitive function in aging and Alzheimer disease mouse models.

Wilson, Edward N; Wang, Congcong; Swarovski, Michelle S; Zera, Kristy A; Ennerfelt, Hannah E; Wang, Qian; Chaney, Aisling; Gauba, Esha; Ramos Benitez, Javier A; Le Guen, Yann; Minhas, Paras S; Panchal, Maharshi; Tan, Yuting J; Blacher, Eran; A Iweka, Chinyere; Cropper, Haley; Jain, Poorva; Liu, Qingkun; Mehta, Swapnil S; Zuckerman, Abigail J; Xin, Matthew; Umans, Jacob; Huang, Jolie; Durairaj, Aarooran S; Serrano, Geidy E; Beach, Thomas G; Greicius, Michael D; James, Michelle L; Buckwalter, Marion S; McReynolds, Melanie R; Rabinowitz, Joshua D; Andreasson, Katrin I.

Nat Neurosci ; 27(5): 873-885, 2024 May.

Article in English | MEDLINE | ID: mdl-38539014

11.

Chrono-Gerontology: Integrating Circadian Rhythms and Aging in Stroke Research.

Kara, Nirit; Iweka, Chinyere Agbaegbu; Blacher, Eran.

Adv Biol (Weinh) ; 7(11): e2300048, 2023 11.

Article in English | MEDLINE | ID: mdl-37409422

12.

Intravital 3D visualization and segmentation of murine neural networks at micron resolution.

Lautman, Ziv; Winetraub, Yonatan; Blacher, Eran; Yu, Caroline; Terem, Itamar; Chibukhchyan, Adelaida; Marshel, James H; de la Zerda, Adam.

Sci Rep ; 12(1): 13130, 2022 07 30.

Article in English | MEDLINE | ID: mdl-35907928

13.

Stromal CD38 regulates outgrowth of primary melanoma and generation of spontaneous metastasis.

Ben Baruch, Bar; Blacher, Eran; Mantsur, Einav; Schwartz, Hila; Vaknine, Hananya; Erez, Neta; Stein, Reuven.

Oncotarget ; 9(61): 31797-31811, 2018 Aug 07.

Article in English | MEDLINE | ID: mdl-30159123

14.

Hyperglycemia drives intestinal barrier dysfunction and risk for enteric infection.

Thaiss, Christoph A; Levy, Maayan; Grosheva, Inna; Zheng, Danping; Soffer, Eliran; Blacher, Eran; Braverman, Sofia; Tengeler, Anouk C; Barak, Oren; Elazar, Maya; Ben-Zeev, Rotem; Lehavi-Regev, Dana; Katz, Meirav N; Pevsner-Fischer, Meirav; Gertler, Arieh; Halpern, Zamir; Harmelin, Alon; Aamar, Suhail; Serradas, Patricia; Grosfeld, Alexandra; Shapiro, Hagit; Geiger, Benjamin; Elinav, Eran.

Science ; 359(6382): 1376-1383, 2018 03 23.

Article in English | MEDLINE | ID: mdl-29519916

15.

Microbiome, metabolites and host immunity.

Levy, Maayan; Blacher, Eran; Elinav, Eran.

Curr Opin Microbiol ; 35: 8-15, 2017 02.

Article in English | MEDLINE | ID: mdl-27883933

16.

Can microbes combat neurodegeneration?

Blacher, Eran.

Science ; 373(6551): 172-173, 2021 Jul 09.

Article in English | MEDLINE | ID: mdl-34244406

17.

Incipient Melanoma Brain Metastases Instigate Astrogliosis and Neuroinflammation.

Schwartz, Hila; Blacher, Eran; Amer, Malak; Livneh, Nir; Abramovitz, Lilach; Klein, Anat; Ben-Shushan, Dikla; Soffer, Shelly; Blazquez, Raquel; Barrantes-Freer, Alonso; Müller, Meike; Müller-Decker, Karin; Stein, Reuven; Tsarfaty, Galia; Satchi-Fainaro, Ronit; Umansky, Viktor; Pukrop, Tobias; Erez, Neta.

Cancer Res ; 76(15): 4359-71, 2016 08 01.

Article in English | MEDLINE | ID: mdl-27261506

18.

Exploring the Effects of Glycosylation and Etherification of the Side Chains of the Anticancer Drug Mitoxantrone.

Shaul, Pazit; Steinbuch, Kfir B; Blacher, Eran; Stein, Reuven; Fridman, Micha.

ChemMedChem ; 10(9): 1528-38, 2015 Sep.

Article in English | MEDLINE | ID: mdl-26235383

19.

CD38 deficiency in the tumor microenvironment attenuates glioma progression and modulates features of tumor-associated microglia/macrophages.

Levy, Ayelet; Blacher, Eran; Vaknine, Hananya; Lund, Frances E; Stein, Reuven; Mayo, Lior.

Neuro Oncol ; 14(8): 1037-49, 2012 Aug.

Article in English | MEDLINE | ID: mdl-22700727

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