Search details
1.
The atypical 'hippocampal' glutamate receptor coupled to phospholipase D that controls stretch-sensitivity in primary mechanosensory nerve endings is homomeric purely metabotropic GluK2.
Exp Physiol
; 109(1): 81-99, 2024 01.
Article
in English
| MEDLINE | ID: mdl-37656490
2.
Parallel buprenorphine phMRI responses in conscious rodents and healthy human subjects.
J Pharmacol Exp Ther
; 345(1): 41-51, 2013 Apr.
Article
in English
| MEDLINE | ID: mdl-23370795
3.
GluK1 antagonists from 6-(carboxy)phenyl decahydroisoquinoline derivatives. SAR and evaluation of a prodrug strategy for oral efficacy in pain models.
Bioorg Med Chem Lett
; 23(23): 6459-62, 2013 Dec 01.
Article
in English
| MEDLINE | ID: mdl-24119554
4.
GluK1 antagonists from 6-(tetrazolyl)phenyl decahydroisoquinoline derivatives: in vitro profile and in vivo analgesic efficacy.
Bioorg Med Chem Lett
; 23(23): 6463-6, 2013 Dec 01.
Article
in English
| MEDLINE | ID: mdl-24140446
5.
Modulation of CNS pain circuitry by intravenous and sublingual doses of buprenorphine.
Neuroimage
; 59(4): 3762-73, 2012 Feb 15.
Article
in English
| MEDLINE | ID: mdl-22119647
6.
Improved characterization of BOLD responses for evoked sensory stimuli.
Neuroimage
; 49(3): 2275-86, 2010 Feb 01.
Article
in English
| MEDLINE | ID: mdl-19854280
7.
Chemogenetics: drug-controlled gene therapies for neural circuit disorders.
Cell Gene Ther Insights
; 6(7): 1079-1094, 2020 Aug.
Article
in English
| MEDLINE | ID: mdl-34422319
8.
ACET is a highly potent and specific kainate receptor antagonist: characterisation and effects on hippocampal mossy fibre function.
Neuropharmacology
; 56(1): 121-30, 2009 Jan.
Article
in English
| MEDLINE | ID: mdl-18789344
9.
A role for Ca2+ stores in kainate receptor-dependent synaptic facilitation and LTP at mossy fiber synapses in the hippocampus.
Neuron
; 39(2): 327-41, 2003 Jul 17.
Article
in English
| MEDLINE | ID: mdl-12873388
10.
Antagonists of GLU(K5)-containing kainate receptors prevent pilocarpine-induced limbic seizures.
Nat Neurosci
; 5(8): 796-804, 2002 Aug.
Article
in English
| MEDLINE | ID: mdl-12080343
11.
Anxiolytic-like effects through a GLUK5 kainate receptor mechanism.
Neuropharmacology
; 52(7): 1482-7, 2007 Jun.
Article
in English
| MEDLINE | ID: mdl-17418283
12.
Synthesis and pharmacological characterization of N3-substituted willardiine derivatives: role of the substituent at the 5-position of the uracil ring in the development of highly potent and selective GLUK5 kainate receptor antagonists.
J Med Chem
; 50(7): 1558-70, 2007 Apr 05.
Article
in English
| MEDLINE | ID: mdl-17348638
13.
Structure-activity relationship studies on N3-substituted willardiine derivatives acting as AMPA or kainate receptor antagonists.
J Med Chem
; 49(8): 2579-92, 2006 Apr 20.
Article
in English
| MEDLINE | ID: mdl-16610801
14.
A role for AMPA receptors in mood disorders.
Biochem Pharmacol
; 71(9): 1273-88, 2006 Apr 28.
Article
in English
| MEDLINE | ID: mdl-16442080
15.
In vitro and in vivo studies in rats with LY293558 suggest AMPA/kainate receptor blockade as a novel potential mechanism for the therapeutic treatment of anxiety disorders.
Psychopharmacology (Berl)
; 185(2): 240-7, 2006 Apr.
Article
in English
| MEDLINE | ID: mdl-16470401
16.
Pharmacological Modulation of GluK1 and GluK2 by NETO1, NETO2, and PSD95.
Assay Drug Dev Technol
; 14(2): 131-43, 2016 Mar.
Article
in English
| MEDLINE | ID: mdl-26991362
17.
Synthesis and pharmacology of willardiine derivatives acting as antagonists of kainate receptors.
J Med Chem
; 48(24): 7867-81, 2005 Dec 01.
Article
in English
| MEDLINE | ID: mdl-16302825
18.
Two prodrugs of potent and selective GluR5 kainate receptor antagonists actives in three animal models of pain.
J Med Chem
; 48(13): 4200-3, 2005 Jun 30.
Article
in English
| MEDLINE | ID: mdl-15974569
19.
Test-retest reliability of evoked heat stimulation BOLD fMRI.
J Neurosci Methods
; 253: 38-46, 2015 Sep 30.
Article
in English
| MEDLINE | ID: mdl-26072245
20.
AMPA receptor potentiators for the treatment of CNS disorders.
Curr Drug Targets CNS Neurol Disord
; 3(3): 181-94, 2004 Jun.
Article
in English
| MEDLINE | ID: mdl-15180479