Search details
1.
Spinal muscular atrophy associated with progressive myoclonic epilepsy is caused by mutations in ASAH1.
Am J Hum Genet
; 91(1): 5-14, 2012 Jul 13.
Article
in English
| MEDLINE | ID: mdl-22703880
2.
Molecular basis of acid ceramidase deficiency in a neonatal form of Farber disease: identification of the first large deletion in ASAH1 gene.
Mol Genet Metab
; 109(3): 276-81, 2013 Jul.
Article
in English
| MEDLINE | ID: mdl-23707712
3.
Mice doubly-deficient in lysosomal hexosaminidase A and neuraminidase 4 show epileptic crises and rapid neuronal loss.
PLoS Genet
; 6(9): e1001118, 2010 Sep 16.
Article
in English
| MEDLINE | ID: mdl-20862357
4.
Sphingolipid paracrine signaling impairs keratinocyte adhesion to promote melanoma invasion.
Cell Rep
; 42(12): 113586, 2023 12 26.
Article
in English
| MEDLINE | ID: mdl-38113139
5.
Mice deficient in Neu4 sialidase exhibit abnormal ganglioside catabolism and lysosomal storage.
Hum Mol Genet
; 17(11): 1556-68, 2008 Jun 01.
Article
in English
| MEDLINE | ID: mdl-18270209
6.
Resistance of melanoma to immune checkpoint inhibitors is overcome by targeting the sphingosine kinase-1.
Nat Commun
; 11(1): 437, 2020 01 23.
Article
in English
| MEDLINE | ID: mdl-31974367
7.
Ceramide production associated with retinal apoptosis after retinal detachment.
Graefes Arch Clin Exp Ophthalmol
; 247(2): 215-24, 2009 Feb.
Article
in English
| MEDLINE | ID: mdl-18958490
8.
Sphingomyelin Synthase 1 (SMS1) Downregulation Is Associated With Sphingolipid Reprogramming and a Worse Prognosis in Melanoma.
Front Pharmacol
; 10: 443, 2019.
Article
in English
| MEDLINE | ID: mdl-31114500
9.
In vivo delivery of human acid ceramidase via cord blood transplantation and direct injection of lentivirus as novel treatment approaches for Farber disease.
Mol Genet Metab
; 95(3): 133-41, 2008 Nov.
Article
in English
| MEDLINE | ID: mdl-18805722
10.
The sphingosine 1-phosphate receptor S1P2 triggers hepatic wound healing.
FASEB J
; 21(9): 2005-13, 2007 Jul.
Article
in English
| MEDLINE | ID: mdl-17341687
11.
Sphingolipids in macroautophagy.
Methods Mol Biol
; 445: 159-73, 2008.
Article
in English
| MEDLINE | ID: mdl-18425450
12.
Downregulation of sphingosine kinase-1 induces protective tumor immunity by promoting M1 macrophage response in melanoma.
Oncotarget
; 7(44): 71873-71886, 2016 Nov 01.
Article
in English
| MEDLINE | ID: mdl-27708249
13.
The absence of functional glucosylceramide synthase does not sensitize melanoma cells for anticancer drugs.
FASEB J
; 17(9): 1144-6, 2003 Jun.
Article
in English
| MEDLINE | ID: mdl-12692077
14.
The pro-inflammatory action of tumour necrosis factor-α in non-alcoholic steatohepatitis is independent of the NSMAF gene product.
Dig Liver Dis
; 45(2): 147-54, 2013 Feb.
Article
in English
| MEDLINE | ID: mdl-23044079
15.
Systemic ceramide accumulation leads to severe and varied pathological consequences.
EMBO Mol Med
; 5(6): 827-42, 2013 Jun.
Article
in English
| MEDLINE | ID: mdl-23681708
16.
Production of multiple brain-like ganglioside species is dispensable for fas-induced apoptosis of lymphoid cells.
PLoS One
; 6(5): e19974, 2011.
Article
in English
| MEDLINE | ID: mdl-21629700
17.
Autologous transplantation of lentivector/acid ceramidase-transduced hematopoietic cells in nonhuman primates.
Hum Gene Ther
; 22(6): 679-87, 2011 Jun.
Article
in English
| MEDLINE | ID: mdl-21280983
18.
Role of JNK1-dependent Bcl-2 phosphorylation in ceramide-induced macroautophagy.
J Biol Chem
; 284(5): 2719-2728, 2009 Jan 30.
Article
in English
| MEDLINE | ID: mdl-19029119
19.
IL-6 deficiency attenuates murine diet-induced non-alcoholic steatohepatitis.
PLoS One
; 4(11): e7929, 2009 Nov 20.
Article
in English
| MEDLINE | ID: mdl-19936233
20.
The natural marine anhydrophytosphingosine, Jaspine B, induces apoptosis in melanoma cells by interfering with ceramide metabolism.
Biochem Pharmacol
; 78(5): 477-85, 2009 Sep 01.
Article
in English
| MEDLINE | ID: mdl-19433071