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1.
A TMPRSS2 inhibitor acts as a pan-SARS-CoV-2 prophylactic and therapeutic.
Nature
; 605(7909): 340-348, 2022 05.
Article
in English
| MEDLINE | ID: mdl-35344983
2.
Following your gut: the emerging role of the gut microbiota in predicting and treating immune-related adverse events.
Curr Opin Oncol
; 35(4): 248-253, 2023 07 01.
Article
in English
| MEDLINE | ID: mdl-37222188
3.
Physiologic colonic uptake of 18F-FDG on PET/CT is associated with clinical response and gut microbiome composition in patients with advanced non-small cell lung cancer treated with immune checkpoint inhibitors.
Eur J Nucl Med Mol Imaging
; 48(5): 1550-1559, 2021 05.
Article
in English
| MEDLINE | ID: mdl-33128571
4.
Transcriptome analysis reveals TMPRSS6 isoforms with distinct functionalities.
J Cell Mol Med
; 22(4): 2498-2509, 2018 04.
Article
in English
| MEDLINE | ID: mdl-29441715
5.
The type II transmembrane serine protease matriptase cleaves the amyloid precursor protein and reduces its processing to ß-amyloid peptide.
J Biol Chem
; 292(50): 20669-20682, 2017 12 15.
Article
in English
| MEDLINE | ID: mdl-29054928
6.
The serine protease-mediated increase in intestinal epithelial barrier function is dependent on occludin and requires an intact tight junction.
Am J Physiol Gastrointest Liver Physiol
; 311(3): G466-79, 2016 09 01.
Article
in English
| MEDLINE | ID: mdl-27492333
7.
Prostasin is required for matriptase activation in intestinal epithelial cells to regulate closure of the paracellular pathway.
J Biol Chem
; 288(15): 10328-37, 2013 Apr 12.
Article
in English
| MEDLINE | ID: mdl-23443662
8.
Matriptase proteolytically activates influenza virus and promotes multicycle replication in the human airway epithelium.
J Virol
; 87(8): 4237-51, 2013 Apr.
Article
in English
| MEDLINE | ID: mdl-23365447
9.
Visualizing Heterogeneous Pulmonary Ventilation. Respiratory Failure due to an Anterior Mediastinal Mass.
Am J Respir Crit Care Med
; 198(7): e88-e89, 2018 10 01.
Article
in English
| MEDLINE | ID: mdl-29924939
10.
Optimization of Ketobenzothiazole-Based Type II Transmembrane Serine Protease Inhibitors to Block H1N1 Influenza Virus Replication.
ChemMedChem
; 19(2): e202300458, 2024 01 15.
Article
in English
| MEDLINE | ID: mdl-37864572
11.
Nanomolar anti-SARS-CoV-2 Omicron activity of the host-directed TMPRSS2 inhibitor N-0385 and synergistic action with direct-acting antivirals.
Antiviral Res
; 225: 105869, 2024 May.
Article
in English
| MEDLINE | ID: mdl-38548023
12.
A phase 1 study of concurrent cabozantinib and cetuximab in recurrent or metastatic head and neck squamous cell cancer.
Oral Oncol
; 154: 106861, 2024 May 24.
Article
in English
| MEDLINE | ID: mdl-38795600
13.
Gut microbiome predicts gastrointestinal toxicity outcomes from chemoradiation therapy in patients with head and neck squamous cell carcinoma.
Oral Oncol
; 148: 106623, 2024 Jan.
Article
in English
| MEDLINE | ID: mdl-38006691
14.
RET-Altered Cancers-A Tumor-Agnostic Review of Biology, Diagnosis and Targeted Therapy Activity.
Cancers (Basel)
; 15(16)2023 Aug 17.
Article
in English
| MEDLINE | ID: mdl-37627175
15.
Essential role of endocytosis of the type II transmembrane serine protease TMPRSS6 in regulating its functionality.
J Biol Chem
; 286(33): 29035-29043, 2011 Aug 19.
Article
in English
| MEDLINE | ID: mdl-21724843
16.
PI3K Inhibition for Squamous Cell Head and Neck Carcinoma.
Cancer J
; 28(5): 369-376, 2022.
Article
in English
| MEDLINE | ID: mdl-36165725
17.
Targeting HRAS in Head and Neck Cancer: Lessons From the Past and Future Promise.
Cancer J
; 28(5): 363-368, 2022.
Article
in English
| MEDLINE | ID: mdl-36165724
18.
Functionally impaired isoforms regulate TMPRSS6 proteolytic activity.
PLoS One
; 17(8): e0273825, 2022.
Article
in English
| MEDLINE | ID: mdl-36044454
19.
Upfront DPYD Genotyping and Toxicity Associated with Fluoropyrimidine-Based Concurrent Chemoradiotherapy for Oropharyngeal Carcinomas: A Work in Progress.
Curr Oncol
; 29(2): 497-509, 2022 01 26.
Article
in English
| MEDLINE | ID: mdl-35200545
20.
Intestinal Akkermansia muciniphila predicts clinical response to PD-1 blockade in patients with advanced non-small-cell lung cancer.
Nat Med
; 28(2): 315-324, 2022 02.
Article
in English
| MEDLINE | ID: mdl-35115705