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1.
NOXA genetic amplification or pharmacologic induction primes lymphoma cells to BCL2 inhibitor-induced cell death.
Proc Natl Acad Sci U S A
; 115(47): 12034-12039, 2018 11 20.
Article
in English
| MEDLINE | ID: mdl-30404918
2.
The novel proautophagy anticancer drug ABTL0812 potentiates chemotherapy in adenocarcinoma and squamous nonsmall cell lung cancer.
Int J Cancer
; 147(4): 1163-1179, 2020 08 15.
Article
in English
| MEDLINE | ID: mdl-31943158
3.
SUMOylation Is Required for ERK5 Nuclear Translocation and ERK5-Mediated Cancer Cell Proliferation.
Int J Mol Sci
; 21(6)2020 Mar 23.
Article
in English
| MEDLINE | ID: mdl-32209980
4.
Oncosuppressive functions of tribbles pseudokinase 3.
Biochem Soc Trans
; 43(5): 1122-6, 2015 Oct.
Article
in English
| MEDLINE | ID: mdl-26517935
5.
Synthetic lethality of drug-induced polyploidy and BCL-2 inhibition in lymphoma.
Nat Commun
; 14(1): 1522, 2023 03 18.
Article
in English
| MEDLINE | ID: mdl-36934096
6.
Brain specific kinase-1 BRSK1/SAD-B associates with lipid rafts: modulation of kinase activity by lipid environment.
Biochim Biophys Acta
; 1811(12): 1124-35, 2011 Dec.
Article
in English
| MEDLINE | ID: mdl-22020259
7.
TP53 mutations and RNA-binding protein MUSASHI-2 drive resistance to PRMT5-targeted therapy in B-cell lymphoma.
Nat Commun
; 13(1): 5676, 2022 09 27.
Article
in English
| MEDLINE | ID: mdl-36167829
8.
The anti-cancer drug ABTL0812 induces ER stress-mediated cytotoxic autophagy by increasing dihydroceramide levels in cancer cells.
Autophagy
; 17(6): 1349-1366, 2021 06.
Article
in English
| MEDLINE | ID: mdl-32397857
9.
The antitumour drug ABTL0812 impairs neuroblastoma growth through endoplasmic reticulum stress-mediated autophagy and apoptosis.
Cell Death Dis
; 11(9): 773, 2020 09 17.
Article
in English
| MEDLINE | ID: mdl-32943619
10.
BET Inhibition-Induced GSK3ß Feedback Enhances Lymphoma Vulnerability to PI3K Inhibitors.
Cell Rep
; 24(8): 2155-2166, 2018 08 21.
Article
in English
| MEDLINE | ID: mdl-30134175
11.
Structural and Atropisomeric Factors Governing the Selectivity of Pyrimido-benzodiazipinones as Inhibitors of Kinases and Bromodomains.
ACS Chem Biol
; 13(9): 2438-2448, 2018 09 21.
Article
in English
| MEDLINE | ID: mdl-30102854
12.
ERK5 and Cell Proliferation: Nuclear Localization Is What Matters.
Front Cell Dev Biol
; 4: 105, 2016.
Article
in English
| MEDLINE | ID: mdl-27713878
13.
The New Antitumor Drug ABTL0812 Inhibits the Akt/mTORC1 Axis by Upregulating Tribbles-3 Pseudokinase.
Clin Cancer Res
; 22(10): 2508-19, 2016 05 15.
Article
in English
| MEDLINE | ID: mdl-26671995
14.
Canonical and kinase activity-independent mechanisms for extracellular signal-regulated kinase 5 (ERK5) nuclear translocation require dissociation of Hsp90 from the ERK5-Cdc37 complex.
Mol Cell Biol
; 33(8): 1671-86, 2013 Apr.
Article
in English
| MEDLINE | ID: mdl-23428871
15.
X-ray crystal structure of ERK5 (MAPK7) in complex with a specific inhibitor.
J Med Chem
; 56(11): 4413-21, 2013 Jun 13.
Article
in English
| MEDLINE | ID: mdl-23656407
16.
Structural determinants for ERK5 (MAPK7) and leucine rich repeat kinase 2 activities of benzo[e]pyrimido-[5,4-b]diazepine-6(11H)-ones.
Eur J Med Chem
; 70: 758-67, 2013.
Article
in English
| MEDLINE | ID: mdl-24239623
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