Search | Virtual Health Library

1.

Hierarchy for targeting prosurvival BCL2 family proteins in multiple myeloma: pivotal role of MCL1.

Gong, Jia-Nan; Khong, Tiffany; Segal, David; Yao, Yuan; Riffkin, Chris D; Garnier, Jean-Marc; Khaw, Seong Lin; Lessene, Guillaume; Spencer, Andrew; Herold, Marco J; Roberts, Andrew W; Huang, David C S.

Blood ; 128(14): 1834-1844, 2016 10 06.

Article in English | MEDLINE | ID: mdl-27465916

2.

Activation of the pseudokinase MLKL unleashes the four-helix bundle domain to induce membrane localization and necroptotic cell death.

Hildebrand, Joanne M; Tanzer, Maria C; Lucet, Isabelle S; Young, Samuel N; Spall, Sukhdeep K; Sharma, Pooja; Pierotti, Catia; Garnier, Jean-Marc; Dobson, Renwick C J; Webb, Andrew I; Tripaydonis, Anne; Babon, Jeffrey J; Mulcair, Mark D; Scanlon, Martin J; Alexander, Warren S; Wilks, Andrew F; Czabotar, Peter E; Lessene, Guillaume; Murphy, James M; Silke, John.

Proc Natl Acad Sci U S A ; 111(42): 15072-7, 2014 Oct 21.

Article in English | MEDLINE | ID: mdl-25288762

3.

Human RIPK3 maintains MLKL in an inactive conformation prior to cell death by necroptosis.

Meng, Yanxiang; Davies, Katherine A; Fitzgibbon, Cheree; Young, Samuel N; Garnish, Sarah E; Horne, Christopher R; Luo, Cindy; Garnier, Jean-Marc; Liang, Lung-Yu; Cowan, Angus D; Samson, Andre L; Lessene, Guillaume; Sandow, Jarrod J; Czabotar, Peter E; Murphy, James M.

Nat Commun ; 12(1): 6783, 2021 11 22.

Article in English | MEDLINE | ID: mdl-34811356

4.

Tropheryma whipplei in children with gastroenteritis.

Raoult, Didier; Fenollar, Florence; Rolain, Jean Marc; Minodier, Philippe; Bosdure, Emmanuelle; Li, Wenjun; Garnier, Jean Marc; Richet, Herve.

Emerg Infect Dis ; 16(5): 776-82, 2010 May.

Article in English | MEDLINE | ID: mdl-20409366

5.

Mechanistic investigations of multidentate organocatalyst-promoted counterion catalysis for fast and enantioselective aza-Morita-Baylis-Hillman reactions at ambient temperature.

Anstiss, Christopher; Garnier, Jean-Marc; Liu, Fei.

Org Biomol Chem ; 8(19): 4400-7, 2010 Oct 07.

Article in English | MEDLINE | ID: mdl-20714662

6.

Potent Inhibition of Necroptosis by Simultaneously Targeting Multiple Effectors of the Pathway.

Pierotti, Catia L; Tanzer, Maria C; Jacobsen, Annette V; Hildebrand, Joanne M; Garnier, Jean-Marc; Sharma, Pooja; Lucet, Isabelle S; Cowan, Angus D; Kersten, Wilhelmus J A; Luo, Meng-Xiao; Liang, Lung-Yu; Fitzgibbon, Cheree; Garnish, Sarah E; Hempel, Anne; Nachbur, Ueli; Huang, David C S; Czabotar, Peter E; Silke, John; van Delft, Mark F; Murphy, James M; Lessene, Guillaume.

ACS Chem Biol ; 15(10): 2702-2713, 2020 10 16.

Article in English | MEDLINE | ID: mdl-32902249

7.

Trifunctional organocatalyst-promoted counterion catalysis for fast and enantioselective aza-Morita-Baylis-Hillman reactions at ambient temperature.

Garnier, Jean-Marc; Liu, Fei.

Org Biomol Chem ; 7(7): 1272-5, 2009 Apr 07.

Article in English | MEDLINE | ID: mdl-19300807

8.

Cutaneous leishmaniasis treated with azithromycin in a child.

Minodier, Philippe; Zambelli, Laurent; Mary, Charles; Faraut, Françoise; Garnier, Jean-Marc; Berbis, Philippe.

Pediatr Infect Dis J ; 27(1): 80-1, 2008 Jan.

Article in English | MEDLINE | ID: mdl-18162948

9.

Dual inhibition of BCL-XL and MCL-1 is required to induce tumour regression in lung squamous cell carcinomas sensitive to FGFR inhibition.

Weeden, Clare E; Ah-Cann, Casey; Holik, Aliaksei Z; Pasquet, Julie; Garnier, Jean-Marc; Merino, Delphine; Lessene, Guillaume; Asselin-Labat, Marie-Liesse.

Oncogene ; 37(32): 4475-4488, 2018 08.

Article in English | MEDLINE | ID: mdl-29743589

10.

The BH3-only proteins BIM and PUMA are not critical for the reticulocyte apoptosis caused by loss of the pro-survival protein BCL-XL.

Delbridge, Alex Rd; Aubrey, Brandon J; Hyland, Craig; Bernardini, Jonathan P; Di Rago, Ladina; Garnier, Jean-Marc; Lessene, Guillaume; Strasser, Andreas; Alexander, Warren S; Grabow, Stephanie.

Cell Death Dis ; 8(7): e2914, 2017 07 06.

Article in English | MEDLINE | ID: mdl-28682312

11.

Design, Synthesis, and Biological Activity of 1,2,3-Triazolobenzodiazepine BET Bromodomain Inhibitors.

Sharp, Phillip P; Garnier, Jean-Marc; Hatfaludi, Tamas; Xu, Zhen; Segal, David; Jarman, Kate E; Jousset, Hélène; Garnham, Alexandra; Feutrill, John T; Cuzzupe, Anthony; Hall, Peter; Taylor, Scott; Walkley, Carl R; Tyler, Dean; Dawson, Mark A; Czabotar, Peter; Wilks, Andrew F; Glaser, Stefan; Huang, David C S; Burns, Christopher J.

ACS Med Chem Lett ; 8(12): 1298-1303, 2017 Dec 14.

Article in English | MEDLINE | ID: mdl-29259751

12.

Cisplatin Increases Sensitivity to FGFR Inhibition in Patient-Derived Xenograft Models of Lung Squamous Cell Carcinoma.

Weeden, Clare E; Holik, Aliaksei Z; Young, Richard J; Ma, Stephen B; Garnier, Jean-Marc; Fox, Stephen B; Antippa, Phillip; Irving, Louis B; Steinfort, Daniel P; Wright, Gavin M; Russell, Prudence A; Ritchie, Matthew E; Burns, Christopher J; Solomon, Benjamin; Asselin-Labat, Marie-Liesse.

Mol Cancer Ther ; 16(8): 1610-1622, 2017 08.

Article in English | MEDLINE | ID: mdl-28611104

13.

BAX-BAK1-independent LC3B lipidation by BH3 mimetics is unrelated to BH3 mimetic activity and has only minimal effects on autophagic flux.

Reljic, Boris; Conos, Stephanie; Lee, Erinna F; Garnier, Jean-Marc; Dong, Li; Lessene, Guillaume; Fairlie, W Douglas; Vaux, David L; Lindqvist, Lisa M.

Autophagy ; 12(7): 1083-93, 2016 07 02.

Article in English | MEDLINE | ID: mdl-27172402

14.

Computationally designed high specificity inhibitors delineate the roles of BCL2 family proteins in cancer.

Berger, Stephanie; Procko, Erik; Margineantu, Daciana; Lee, Erinna F; Shen, Betty W; Zelter, Alex; Silva, Daniel-Adriano; Chawla, Kusum; Herold, Marco J; Garnier, Jean-Marc; Johnson, Richard; MacCoss, Michael J; Lessene, Guillaume; Davis, Trisha N; Stayton, Patrick S; Stoddard, Barry L; Fairlie, W Douglas; Hockenbery, David M; Baker, David.

Elife ; 52016 11 02.

Article in English | MEDLINE | ID: mdl-27805565

15.

Liposomal amphotericin B in the treatment of visceral leishmaniasis in immunocompetent patients.

Minodier, Philippe; Retornaz, Karine; Horelt, Alexia; Garnier, Jean-Marc.

Fundam Clin Pharmacol ; 17(2): 183-8, 2003 Apr.

Article in English | MEDLINE | ID: mdl-12667228

16.

Antimosquito precautions and medical chemoprophylaxis in French children with malaria.

Minodier, Philippe; Kone-Paut, Isabelle; Nassur, Assimouna; Launay, Frank; Jouve, Jean-Luc; Hassid, Sophie; Retornaz, Karine; Garnier, Jean-Marc.

J Travel Med ; 10(6): 318-23, 2003.

Article in English | MEDLINE | ID: mdl-14642197

17.

[Children immunization in France: an update]. / Actualités des vaccinations chez l'enfant.

Garnier, Jean-Marc; Retornaz, Karine; Noël, Guilhem; Minodier, Philippe.

Rev Prat ; 54(5): 489, 491-8, 2004 Mar 15.

Article in French | MEDLINE | ID: mdl-15176505

18.

BET bromodomain inhibitors: a patent review.

Garnier, Jean-Marc; Sharp, Phillip P; Burns, Christopher J.

Expert Opin Ther Pat ; 24(2): 185-99, 2014 Feb.

Article in English | MEDLINE | ID: mdl-24261714

19.

Acquired hydrocephalus caused by a variant lymphocytic choriomeningitis virus.

Charrel, Remi N; Retornaz, Karine; Emonet, Sébastien; Noel, Guilhem; Chaumoitre, Kathia; Minodier, Philippe; Girard, Nadine; Garnier, Jean-Marc; de Lamballerie, Xavier.

Arch Intern Med ; 166(18): 2044-6, 2006 Oct 09.

Article in English | MEDLINE | ID: mdl-17030840

20.

[Mumps]. / Oreillons.

Garnier, Jean-Marc.

Rev Prat ; 56(1): 103-5, 2006 Jan 15.

Article in French | MEDLINE | ID: mdl-16548256

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