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1.
CRISPR Activation Reverses Haploinsufficiency and Functional Deficits Caused by TTN Truncation Variants.
Circulation
; 149(16): 1285-1297, 2024 Apr 16.
Article
in English
| MEDLINE | ID: mdl-38235591
2.
Distinct effects of two hearing loss-associated mutations in the sarcomeric myosin MYH7b.
J Biol Chem
; 299(5): 104631, 2023 05.
Article
in English
| MEDLINE | ID: mdl-36963494
3.
Functional divergence of the sarcomeric myosin, MYH7b, supports species-specific biological roles.
J Biol Chem
; 299(1): 102657, 2023 01.
Article
in English
| MEDLINE | ID: mdl-36334627
4.
Multiscale biophysical models of cardiomyopathies reveal complexities challenging existing dogmas.
Biophys J
; 122(24): 4632-4634, 2023 12 19.
Article
in English
| MEDLINE | ID: mdl-38006882
5.
Single-molecule mechanics and kinetics of cardiac myosin interacting with regulated thin filaments.
Biophys J
; 122(12): 2544-2555, 2023 06 20.
Article
in English
| MEDLINE | ID: mdl-37165621
6.
Functional assays reveal the pathogenic mechanism of a de novo tropomyosin variant identified in patient with dilated cardiomyopathy.
J Mol Cell Cardiol
; 176: 58-67, 2023 03.
Article
in English
| MEDLINE | ID: mdl-36739943
7.
Myofilament glycation in diabetes reduces contractility by inhibiting tropomyosin movement, is rescued by cMyBPC domains.
J Mol Cell Cardiol
; 162: 1-9, 2022 01.
Article
in English
| MEDLINE | ID: mdl-34487755
8.
Cardiac myosin contraction and mechanotransduction in health and disease.
J Biol Chem
; 297(5): 101297, 2021 11.
Article
in English
| MEDLINE | ID: mdl-34634306
9.
Disrupted mechanobiology links the molecular and cellular phenotypes in familial dilated cardiomyopathy.
Proc Natl Acad Sci U S A
; 116(36): 17831-17840, 2019 09 03.
Article
in English
| MEDLINE | ID: mdl-31427533
10.
Computational Tool for Ensemble Averaging of Single-Molecule Data.
Biophys J
; 120(1): 10-20, 2021 01 05.
Article
in English
| MEDLINE | ID: mdl-33248132
11.
Beyond genomics-technological advances improving the molecular characterization and precision treatment of heart failure.
Heart Fail Rev
; 26(2): 405-415, 2021 03.
Article
in English
| MEDLINE | ID: mdl-32885327
12.
Computational Tool to Study Perturbations in Muscle Regulation and Its Application to Heart Disease.
Biophys J
; 116(12): 2246-2252, 2019 06 18.
Article
in English
| MEDLINE | ID: mdl-31126584
13.
Cooperative Changes in Solvent Exposure Identify Cryptic Pockets, Switches, and Allosteric Coupling.
Biophys J
; 116(5): 818-830, 2019 03 05.
Article
in English
| MEDLINE | ID: mdl-30744991
14.
Mechanochemical tuning of myosin-I by the N-terminal region.
Proc Natl Acad Sci U S A
; 112(26): E3337-44, 2015 Jun 30.
Article
in English
| MEDLINE | ID: mdl-26056287
15.
An actin filament population defined by the tropomyosin Tpm3.1 regulates glucose uptake.
Traffic
; 16(7): 691-711, 2015 Jul.
Article
in English
| MEDLINE | ID: mdl-25783006
16.
A vertebrate myosin-I structure reveals unique insights into myosin mechanochemical tuning.
Proc Natl Acad Sci U S A
; 111(6): 2116-21, 2014 Feb 11.
Article
in English
| MEDLINE | ID: mdl-24469830
17.
A Perspective on the Role of Myosins as Mechanosensors.
Biophys J
; 110(12): 2568-2576, 2016 Jun 21.
Article
in English
| MEDLINE | ID: mdl-27332116
18.
MEMLET: An Easy-to-Use Tool for Data Fitting and Model Comparison Using Maximum-Likelihood Estimation.
Biophys J
; 111(2): 273-282, 2016 Jul 26.
Article
in English
| MEDLINE | ID: mdl-27463130
19.
Myosin IC generates power over a range of loads via a new tension-sensing mechanism.
Proc Natl Acad Sci U S A
; 109(37): E2433-40, 2012 Sep 11.
Article
in English
| MEDLINE | ID: mdl-22908250
20.
Inherent force-dependent properties of ß-cardiac myosin contribute to the force-velocity relationship of cardiac muscle.
Biophys J
; 107(12): L41-L44, 2014 Dec 16.
Article
in English
| MEDLINE | ID: mdl-25517169