Search details
1.
Somatic genomic changes in single Alzheimer's disease neurons.
Nature
; 604(7907): 714-722, 2022 04.
Article
in English
| MEDLINE | ID: mdl-35444284
2.
Persistent DNA damage associated with ATM kinase deficiency promotes microglial dysfunction.
Nucleic Acids Res
; 50(5): 2700-2718, 2022 03 21.
Article
in English
| MEDLINE | ID: mdl-35212385
3.
H2AZ is enriched at polycomb complex target genes in ES cells and is necessary for lineage commitment.
Cell
; 135(4): 649-61, 2008 Nov 14.
Article
in English
| MEDLINE | ID: mdl-18992931
4.
Genome aging: somatic mutation in the brain links age-related decline with disease and nominates pathogenic mechanisms.
Hum Mol Genet
; 28(R2): R197-R206, 2019 10 15.
Article
in English
| MEDLINE | ID: mdl-31578549
5.
APP gene copy number changes reflect exogenous contamination.
Nature
; 584(7821): E20-E28, 2020 08.
Article
in English
| MEDLINE | ID: mdl-32814883
6.
PaSD-qc: quality control for single cell whole-genome sequencing data using power spectral density estimation.
Nucleic Acids Res
; 46(4): e20, 2018 02 28.
Article
in English
| MEDLINE | ID: mdl-29186545
7.
Corrigendum: Genome aging: somatic mutation in the brain links age-related decline with disease and nominates pathogenic mechanisms.
Hum Mol Genet
; 29(3): 527, 2020 Feb 01.
Article
in English
| MEDLINE | ID: mdl-31778186
8.
SOX2 co-occupies distal enhancer elements with distinct POU factors in ESCs and NPCs to specify cell state.
PLoS Genet
; 9(2): e1003288, 2013.
Article
in English
| MEDLINE | ID: mdl-23437007
9.
ATM-deficiency-induced microglial activation promotes neurodegeneration in ataxia-telangiectasia.
Cell Rep
; 43(1): 113622, 2024 01 23.
Article
in English
| MEDLINE | ID: mdl-38159274
10.
Histone H3K27ac separates active from poised enhancers and predicts developmental state.
Proc Natl Acad Sci U S A
; 107(50): 21931-6, 2010 Dec 14.
Article
in English
| MEDLINE | ID: mdl-21106759
11.
Single-cell transcriptomic and genomic changes in the aging human brain.
bioRxiv
; 2023 Nov 07.
Article
in English
| MEDLINE | ID: mdl-37986960
12.
Cell lineage analysis with somatic mutations reveals late divergence of neuronal cell types and cortical areas in human cerebral cortex.
bioRxiv
; 2023 Nov 06.
Article
in English
| MEDLINE | ID: mdl-37986891
13.
Reprogramming of postnatal neurons into induced pluripotent stem cells by defined factors.
Stem Cells
; 29(6): 992-1000, 2011 Jun.
Article
in English
| MEDLINE | ID: mdl-21563275
14.
The two faces of DNA oxidation in genomic and functional mosaicism during aging in human neurons.
Front Aging
; 3: 991460, 2022.
Article
in English
| MEDLINE | ID: mdl-36313183
15.
Prevalence and mechanisms of somatic deletions in single human neurons during normal aging and in DNA repair disorders.
Nat Commun
; 13(1): 5918, 2022 10 07.
Article
in English
| MEDLINE | ID: mdl-36207339
16.
Somatic mutations in single human cardiomyocytes reveal age-associated DNA damage and widespread oxidative genotoxicity.
Nat Aging
; 2(8): 714-725, 2022 08.
Article
in English
| MEDLINE | ID: mdl-36051457
17.
Single-cell genome sequencing of human neurons identifies somatic point mutation and indel enrichment in regulatory elements.
Nat Genet
; 54(10): 1564-1571, 2022 10.
Article
in English
| MEDLINE | ID: mdl-36163278
18.
Linked-read analysis identifies mutations in single-cell DNA-sequencing data.
Nat Genet
; 51(4): 749-754, 2019 04.
Article
in English
| MEDLINE | ID: mdl-30886424
19.
Aging and neurodegeneration are associated with increased mutations in single human neurons.
Science
; 359(6375): 555-559, 2018 02 02.
Article
in English
| MEDLINE | ID: mdl-29217584
20.
Editorial: Somatic mutations, genome mosaicism and aging.
Front Aging
; 3: 1115408, 2022.
Article
in English
| MEDLINE | ID: mdl-36698749