Search details
1.
Negative DNA supercoiling induces genome-wide Cas9 off-target activity.
Mol Cell
; 83(19): 3533-3545.e5, 2023 Oct 05.
Article
in English
| MEDLINE | ID: mdl-37802026
2.
In vivo CRISPR editing with no detectable genome-wide off-target mutations.
Nature
; 561(7723): 416-419, 2018 09.
Article
in English
| MEDLINE | ID: mdl-30209390
3.
Correction of a urea cycle defect after ex vivo gene editing of human hepatocytes.
Mol Ther
; 29(5): 1903-1917, 2021 05 05.
Article
in English
| MEDLINE | ID: mdl-33484963
4.
Decoding non-random mutational signatures at Cas9 targeted sites.
Nucleic Acids Res
; 46(16): 8417-8434, 2018 09 19.
Article
in English
| MEDLINE | ID: mdl-30032200
5.
In vivo genome and base editing of a human PCSK9 knock-in hypercholesterolemic mouse model.
BMC Biol
; 17(1): 4, 2019 01 15.
Article
in English
| MEDLINE | ID: mdl-30646909
6.
BE-FLARE: a fluorescent reporter of base editing activity reveals editing characteristics of APOBEC3A and APOBEC3B.
BMC Biol
; 16(1): 150, 2018 12 28.
Article
in English
| MEDLINE | ID: mdl-30593278
7.
Small molecule inducers of ABCA1 and apoE that act through indirect activation of the LXR pathway.
J Lipid Res
; 59(5): 830-842, 2018 05.
Article
in English
| MEDLINE | ID: mdl-29563219
8.
A CRISP(e)R view on kidney organoids allows generation of an induced pluripotent stem cell-derived kidney model for drug discovery.
Kidney Int
; 94(6): 1099-1110, 2018 12.
Article
in English
| MEDLINE | ID: mdl-30072040
9.
Obligate ligation-gated recombination (ObLiGaRe): custom-designed nuclease-mediated targeted integration through nonhomologous end joining.
Genome Res
; 23(3): 539-46, 2013 Mar.
Article
in English
| MEDLINE | ID: mdl-23152450
10.
High-efficiency counterselection recombineering for site-directed mutagenesis in bacterial artificial chromosomes.
Nat Methods
; 9(1): 103-9, 2011 Dec 04.
Article
in English
| MEDLINE | ID: mdl-22138824
11.
Targeted isolation of cloned genomic regions by recombineering for haplotype phasing and isogenic targeting.
Nucleic Acids Res
; 39(20): e137, 2011 Nov 01.
Article
in English
| MEDLINE | ID: mdl-21852329
12.
Elevated Adipocyte Membrane Phospholipid Saturation Does Not Compromise Insulin Signaling.
Diabetes
; 72(10): 1350-1363, 2023 10 01.
Article
in English
| MEDLINE | ID: mdl-36580483
13.
Simultaneous inhibition of DNA-PK and PolÏ´ improves integration efficiency and precision of genome editing.
Nat Commun
; 14(1): 4761, 2023 08 14.
Article
in English
| MEDLINE | ID: mdl-37580318
14.
A Type II-B Cas9 nuclease with minimized off-targets and reduced chromosomal translocations in vivo.
Nat Commun
; 14(1): 5474, 2023 09 06.
Article
in English
| MEDLINE | ID: mdl-37673883
15.
Progress and harmonization of gene editing to treat human diseases: Proceeding of COST Action CA21113 GenE-HumDi.
Mol Ther Nucleic Acids
; 34: 102066, 2023 Dec 12.
Article
in English
| MEDLINE | ID: mdl-38034032
16.
Recombineering BAC transgenes for protein tagging.
Methods
; 53(2): 113-9, 2011 Feb.
Article
in English
| MEDLINE | ID: mdl-20868752
17.
Recombineering, transfection, Western, IP and ChIP methods for protein tagging via gene targeting or BAC transgenesis.
Methods
; 53(4): 437-52, 2011 Apr.
Article
in English
| MEDLINE | ID: mdl-21195765
18.
Harnessing DSB repair to promote efficient homology-dependent and -independent prime editing.
Nat Commun
; 13(1): 1240, 2022 03 24.
Article
in English
| MEDLINE | ID: mdl-35332138
19.
TLCD1 and TLCD2 regulate cellular phosphatidylethanolamine composition and promote the progression of non-alcoholic steatohepatitis.
Nat Commun
; 13(1): 6020, 2022 10 14.
Article
in English
| MEDLINE | ID: mdl-36241646
20.
Extensive transcription mis-regulation and membrane defects in AdipoR2-deficient cells challenged with saturated fatty acids.
Biochim Biophys Acta Mol Cell Biol Lipids
; 1866(4): 158884, 2021 04.
Article
in English
| MEDLINE | ID: mdl-33444759