Search details
1.
Design of proteasome inhibitors with oral efficacy in vivo against Plasmodium falciparum and selectivity over the human proteasome.
Proc Natl Acad Sci U S A
; 118(39)2021 09 28.
Article
in English
| MEDLINE | ID: mdl-34548400
2.
Discovery of Potent Antimalarial Type II Kinase Inhibitors with Selectivity over Human Kinases.
J Med Chem
; 67(2): 1460-1480, 2024 Jan 25.
Article
in English
| MEDLINE | ID: mdl-38214254
3.
Antiplasmodial peptaibols act through membrane directed mechanisms.
Cell Chem Biol
; 31(2): 312-325.e9, 2024 Feb 15.
Article
in English
| MEDLINE | ID: mdl-37995692
4.
Human nuclear hormone receptor activity contributes to malaria parasite liver stage development.
Cell Chem Biol
; 30(5): 486-498.e7, 2023 05 18.
Article
in English
| MEDLINE | ID: mdl-37172592
5.
Fast-Killing Tyrosine Amide ((S)-SW228703) with Blood- and Liver-Stage Antimalarial Activity Associated with the Cyclic Amine Resistance Locus (PfCARL).
ACS Infect Dis
; 9(3): 527-539, 2023 03 10.
Article
in English
| MEDLINE | ID: mdl-36763526
6.
Human Polo-like Kinase Inhibitors as Antiplasmodials.
ACS Infect Dis
; 9(4): 1004-1021, 2023 04 14.
Article
in English
| MEDLINE | ID: mdl-36919909
7.
Cytoplasmic isoleucyl tRNA synthetase as an attractive multistage antimalarial drug target.
Sci Transl Med
; 15(686): eadc9249, 2023 03 08.
Article
in English
| MEDLINE | ID: mdl-36888694
8.
Advances in malaria pharmacology and the online guide to MALARIA PHARMACOLOGY: IUPHAR review 38.
Br J Pharmacol
; 180(15): 1899-1929, 2023 08.
Article
in English
| MEDLINE | ID: mdl-37197802
9.
Semi-Synthetic Analogues of Cryptolepine as a Potential Source of Sustainable Drugs for the Treatment of Malaria, Human African Trypanosomiasis, and Cancer.
Front Pharmacol
; 13: 875647, 2022.
Article
in English
| MEDLINE | ID: mdl-35600849
10.
The anticancer human mTOR inhibitor sapanisertib potently inhibits multiple Plasmodium kinases and life cycle stages.
Sci Transl Med
; 14(667): eabo7219, 2022 10 19.
Article
in English
| MEDLINE | ID: mdl-36260689
11.
Chemogenomics identifies acetyl-coenzyme A synthetase as a target for malaria treatment and prevention.
Cell Chem Biol
; 29(2): 191-201.e8, 2022 02 17.
Article
in English
| MEDLINE | ID: mdl-34348113
12.
Rapid diagnosis of Leishmania infection with a portable loopmediated isothermal amplification device.
J Biosci
; 462021.
Article
in English
| MEDLINE | ID: mdl-34635627
13.
PfMFR3: A Multidrug-Resistant Modulator in Plasmodium falciparum.
ACS Infect Dis
; 7(4): 811-825, 2021 04 09.
Article
in English
| MEDLINE | ID: mdl-33715347
14.
Novel Antimalarial Tetrazoles and Amides Active against the Hemoglobin Degradation Pathway in Plasmodium falciparum.
J Med Chem
; 64(5): 2739-2761, 2021 03 11.
Article
in English
| MEDLINE | ID: mdl-33620219
15.
Multistage and transmission-blocking targeted antimalarials discovered from the open-source MMV Pandemic Response Box.
Nat Commun
; 12(1): 269, 2021 01 11.
Article
in English
| MEDLINE | ID: mdl-33431834
16.
Potent Antimalarials with Development Potential Identified by Structure-Guided Computational Optimization of a Pyrrole-Based Dihydroorotate Dehydrogenase Inhibitor Series.
J Med Chem
; 64(9): 6085-6136, 2021 05 13.
Article
in English
| MEDLINE | ID: mdl-33876936
17.
Synthesis and Structure-Activity Relationship of Dual-Stage Antimalarial Pyrazolo[3,4-b]pyridines.
J Med Chem
; 63(20): 11902-11919, 2020 10 22.
Article
in English
| MEDLINE | ID: mdl-32945666
18.
Inhibition of Resistance-Refractory P. falciparum Kinase PKG Delivers Prophylactic, Blood Stage, and Transmission-Blocking Antiplasmodial Activity.
Cell Chem Biol
; 27(7): 806-816.e8, 2020 07 16.
Article
in English
| MEDLINE | ID: mdl-32359426
19.
The mitochondrial SIR2 related protein 2 (SIR2RP2) impacts Leishmania donovani growth and infectivity.
PLoS Negl Trop Dis
; 11(5): e0005590, 2017 May.
Article
in English
| MEDLINE | ID: mdl-28493888
20.
Cryptosporidium parvum has an active hypusine biosynthesis pathway.
Mol Biochem Parasitol
; 195(1): 14-22, 2014 Jun.
Article
in English
| MEDLINE | ID: mdl-24893338