Search details
1.
Biophysical and functional properties of purified glucose-6-phosphatase catalytic subunit 1.
J Biol Chem
; 298(1): 101520, 2022 01.
Article
in English
| MEDLINE | ID: mdl-34952005
2.
Nonsynonymous single-nucleotide polymorphisms in the G6PC2 gene affect protein expression, enzyme activity, and fasting blood glucose.
J Biol Chem
; 298(2): 101534, 2022 02.
Article
in English
| MEDLINE | ID: mdl-34954144
3.
Glucose-6-phosphatase catalytic subunit 2 negatively regulates glucose oxidation and insulin secretion in pancreatic ß-cells.
J Biol Chem
; 298(4): 101729, 2022 04.
Article
in English
| MEDLINE | ID: mdl-35176280
4.
Evidence that Evolution of the Diabetes Susceptibility Gene SLC30A8 that Encodes the Zinc Transporter ZnT8 Drives Variations in Pancreatic Islet Zinc Content in Multiple Species.
J Mol Evol
; 87(4-6): 147-151, 2019 07.
Article
in English
| MEDLINE | ID: mdl-31273433
5.
The Diabetes Susceptibility Gene SLC30A8 that Encodes the Zinc Transporter ZnT8 is a Pseudogene in Guinea Pigs Potentially Contributing to Low Guinea Pig Islet Zinc Content.
J Mol Evol
; 86(9): 613-617, 2018 12.
Article
in English
| MEDLINE | ID: mdl-30392157
6.
Identification of structural motifs critical for human G6PC2 function informed by sequence analysis and an AlphaFold2-predicted model.
Biosci Rep
; 44(1)2024 Jan 31.
Article
in English
| MEDLINE | ID: mdl-38095063
7.
Biochemical and metabolic characterization of a G6PC2 inhibitor.
Biochimie
; 222: 109-122, 2024 Mar 01.
Article
in English
| MEDLINE | ID: mdl-38431189
8.
G6PC1 and G6PC2 influence G6P flux but not HSD11B1 activity.
J Mol Endocrinol
; 71(4)2023 11 01.
Article
in English
| MEDLINE | ID: mdl-37855366
9.
An Enhancer Within Abcb11 Regulates G6pc2 in C57BL/6 Mouse Pancreatic Islets.
Diabetes
; 72(11): 1621-1628, 2023 Nov 01.
Article
in English
| MEDLINE | ID: mdl-37552875
10.
Gluconeogenesis: re-evaluating the FOXO1-PGC-1alpha connection.
Nature
; 443(7111): E10-1, 2006 Oct 05.
Article
in English
| MEDLINE | ID: mdl-17024043
11.
The pancreatic islet ß-cell-enriched transcription factor Pdx-1 regulates Slc30a8 gene transcription through an intronic enhancer.
Biochem J
; 433(1): 95-105, 2011 Jan 01.
Article
in English
| MEDLINE | ID: mdl-20942803
12.
Insulin and epidermal growth factor suppress basal glucose-6-phosphatase catalytic subunit gene transcription through overlapping but distinct mechanisms.
Biochem J
; 417(2): 611-20, 2009 Jan 15.
Article
in English
| MEDLINE | ID: mdl-18847435
13.
Deletion of the mouse Slc30a8 gene encoding zinc transporter-8 results in impaired insulin secretion.
Biochem J
; 421(3): 371-6, 2009 Jul 15.
Article
in English
| MEDLINE | ID: mdl-19450229
14.
G6PC2 confers protection against hypoglycemia upon ketogenic diet feeding and prolonged fasting.
Mol Metab
; 41: 101043, 2020 11.
Article
in English
| MEDLINE | ID: mdl-32569842
15.
Potential positive and negative consequences of ZnT8 inhibition.
J Endocrinol
; 246(2): 189-205, 2020 08.
Article
in English
| MEDLINE | ID: mdl-32485672
16.
Pancreatic islet beta cell-specific deletion of G6pc2 reduces fasting blood glucose.
J Mol Endocrinol
; 64(4): 235-248, 2020 05.
Article
in English
| MEDLINE | ID: mdl-32213654
17.
Correlation between FOXO1a (FKHR) and FOXO3a (FKHRL1) binding and the inhibition of basal glucose-6-phosphatase catalytic subunit gene transcription by insulin.
Mol Endocrinol
; 20(11): 2831-47, 2006 Nov.
Article
in English
| MEDLINE | ID: mdl-16840535
18.
Effects of G6pc2 deletion on body weight and cholesterol in mice.
J Mol Endocrinol
; 58(3): 127-139, 2017 04.
Article
in English
| MEDLINE | ID: mdl-28122818
19.
The glucose-6-phosphatase catalytic subunit gene promoter contains both positive and negative glucocorticoid response elements.
Mol Endocrinol
; 19(12): 3001-22, 2005 Dec.
Article
in English
| MEDLINE | ID: mdl-16037130
20.
Functional Analysis of Mouse G6pc1 Mutations Using a Novel In Situ Assay for Glucose-6-Phosphatase Activity and the Effect of Mutations in Conserved Human G6PC1/G6PC2 Amino Acids on G6PC2 Protein Expression.
PLoS One
; 11(9): e0162439, 2016.
Article
in English
| MEDLINE | ID: mdl-27611587