Search details
1.
Chemical Hybridization of Glucagon and Thyroid Hormone Optimizes Therapeutic Impact for Metabolic Disease.
Cell
; 167(3): 843-857.e14, 2016 Oct 20.
Article
in English
| MEDLINE | ID: mdl-27720451
2.
Influence of Nutritional Status and Leptin Action on Agrp and Pomc Co-Expression in Hypothalamic Melanocortin System Neurons.
Neuroendocrinology
; 112(3): 287-297, 2022.
Article
in English
| MEDLINE | ID: mdl-33906196
3.
Contribution of brown adipose tissue activity to the control of energy balance by GLP-1 receptor signalling in mice.
Diabetologia
; 58(9): 2124-32, 2015 Sep.
Article
in English
| MEDLINE | ID: mdl-26049402
4.
Duodenal nutrient exclusion improves metabolic syndrome and stimulates villus hyperplasia.
Gut
; 63(8): 1238-46, 2014 Aug.
Article
in English
| MEDLINE | ID: mdl-24107591
5.
Hormones and diet, but not body weight, control hypothalamic microglial activity.
Glia
; 62(1): 17-25, 2014 Jan.
Article
in English
| MEDLINE | ID: mdl-24166765
6.
A long-acting LEAP2 analog reduces hepatic steatosis and inflammation and causes marked weight loss in mice.
Mol Metab
; 84: 101950, 2024 Jun.
Article
in English
| MEDLINE | ID: mdl-38697291
7.
Characterization of genetic variants of GIPR reveals a contribution of ß-arrestin to metabolic phenotypes.
Nat Metab
; 2024 Jun 13.
Article
in English
| MEDLINE | ID: mdl-38871982
8.
MLK3 promotes metabolic dysfunction induced by saturated fatty acid-enriched diet.
Am J Physiol Endocrinol Metab
; 305(4): E549-56, 2013 Aug 15.
Article
in English
| MEDLINE | ID: mdl-23860122
9.
Optimization of peptide-based polyagonists for treatment of diabetes and obesity.
Bioorg Med Chem
; 26(10): 2873-2881, 2018 06 01.
Article
in English
| MEDLINE | ID: mdl-29153547
10.
Synaptic input organization of the melanocortin system predicts diet-induced hypothalamic reactive gliosis and obesity.
Proc Natl Acad Sci U S A
; 107(33): 14875-80, 2010 Aug 17.
Article
in English
| MEDLINE | ID: mdl-20679202
11.
The incretin co-agonist tirzepatide requires GIPR for hormone secretion from human islets.
Nat Metab
; 5(6): 945-954, 2023 06.
Article
in English
| MEDLINE | ID: mdl-37277609
12.
Ghrelin-induced adiposity is independent of orexigenic effects.
FASEB J
; 25(8): 2814-22, 2011 Aug.
Article
in English
| MEDLINE | ID: mdl-21543764
13.
Restoration of leptin responsiveness in diet-induced obese mice using an optimized leptin analog in combination with exendin-4 or FGF21.
J Pept Sci
; 18(6): 383-93, 2012 Jun.
Article
in English
| MEDLINE | ID: mdl-22565812
14.
Neural regulation of cholesterol metabolism.
Curr Opin Lipidol
; 22(4): 283-7, 2011 Aug.
Article
in English
| MEDLINE | ID: mdl-21734571
15.
Discovery of a potent GIPR peptide antagonist that is effective in rodent and human systems.
Mol Metab
; 66: 101638, 2022 12.
Article
in English
| MEDLINE | ID: mdl-36400403
16.
Next generation GLP-1/GIP/glucagon triple agonists normalize body weight in obese mice.
Mol Metab
; 63: 101533, 2022 09.
Article
in English
| MEDLINE | ID: mdl-35809773
17.
GLP-1-mediated delivery of tesaglitazar improves obesity and glucose metabolism in male mice.
Nat Metab
; 4(8): 1071-1083, 2022 08.
Article
in English
| MEDLINE | ID: mdl-35995995
18.
CNS leptin action modulates immune response and survival in sepsis.
J Neurosci
; 30(17): 6036-47, 2010 Apr 28.
Article
in English
| MEDLINE | ID: mdl-20427662
19.
Sleeve gastrectomy induces loss of weight and fat mass in obese rats, but does not affect leptin sensitivity.
Gastroenterology
; 138(7): 2426-36, 2436.e1-3, 2010 Jun.
Article
in English
| MEDLINE | ID: mdl-20226189
20.
A new glucagon and GLP-1 co-agonist eliminates obesity in rodents.
Nat Chem Biol
; 5(10): 749-57, 2009 Oct.
Article
in English
| MEDLINE | ID: mdl-19597507