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1.
Modulation of TARP γ8-Containing AMPA Receptors as a Novel Therapeutic Approach for Chronic Pain.
J Pharmacol Exp Ther
; 369(3): 345-363, 2019 06.
Article
in English
| MEDLINE | ID: mdl-30910921
2.
In Vitro Pharmacological Characterization and In Vivo Validation of LSN3172176 a Novel M1 Selective Muscarinic Receptor Agonist Tracer Molecule for Positron Emission Tomography.
J Pharmacol Exp Ther
; 365(3): 602-613, 2018 06.
Article
in English
| MEDLINE | ID: mdl-29643252
3.
Translational Pharmacology of the Metabotropic Glutamate 2 Receptor-Preferring Agonist LY2812223 in the Animal and Human Brain.
J Pharmacol Exp Ther
; 361(1): 190-197, 2017 04.
Article
in English
| MEDLINE | ID: mdl-28138041
4.
Development of a radioligand, [(3)H]LY2119620, to probe the human M(2) and M(4) muscarinic receptor allosteric binding sites.
Mol Pharmacol
; 86(1): 116-23, 2014 Jul.
Article
in English
| MEDLINE | ID: mdl-24807966
5.
Characterization of the novel positive allosteric modulator, LY2119620, at the muscarinic M(2) and M(4) receptors.
Mol Pharmacol
; 86(1): 106-15, 2014 Jul.
Article
in English
| MEDLINE | ID: mdl-24807965
6.
Transmembrane AMPA receptor regulatory proteins and cornichon-2 allosterically regulate AMPA receptor antagonists and potentiators.
J Biol Chem
; 286(15): 13134-42, 2011 Apr 15.
Article
in English
| MEDLINE | ID: mdl-21343286
7.
Pharmacological characterization of LY593093, an M1 muscarinic acetylcholine receptor-selective partial orthosteric agonist.
J Pharmacol Exp Ther
; 338(2): 622-32, 2011 Aug.
Article
in English
| MEDLINE | ID: mdl-21558436
8.
In Vitro and In Vivo Correlation of Hepatic Fraction of Metabolism by P450 in Dogs.
J Pharm Sci
; 108(2): 1017-1026, 2019 02.
Article
in English
| MEDLINE | ID: mdl-30244007
9.
Co-expression of neuropeptide Y Y1 and Y5 receptors results in heterodimerization and altered functional properties.
Biochem Pharmacol
; 74(11): 1652-64, 2007 Dec 03.
Article
in English
| MEDLINE | ID: mdl-17897631
10.
Identification, expression and functional characterization of M4L, a muscarinic acetylcholine M4 receptor splice variant.
PLoS One
; 12(12): e0188330, 2017.
Article
in English
| MEDLINE | ID: mdl-29211764
11.
Structural Determinants of the γ-8 TARP Dependent AMPA Receptor Antagonist.
ACS Chem Neurosci
; 8(12): 2631-2647, 2017 12 20.
Article
in English
| MEDLINE | ID: mdl-28825787
12.
Further Evaluation of Mechanisms Associated with the Antidepressantlike Signature of Scopolamine in Mice.
CNS Neurol Disord Drug Targets
; 16(4): 492-500, 2017.
Article
in English
| MEDLINE | ID: mdl-28294051
13.
Targeted Blockade of TARP-γ8-Associated AMPA Receptors: Anticonvulsant Activity with the Selective Antagonist LY3130481 (CERC-611).
CNS Neurol Disord Drug Targets
; 16(10): 1099-1110, 2017.
Article
in English
| MEDLINE | ID: mdl-29090671
14.
Forebrain-selective AMPA-receptor antagonism guided by TARP γ-8 as an antiepileptic mechanism.
Nat Med
; 22(12): 1496-1501, 2016 12.
Article
in English
| MEDLINE | ID: mdl-27820603
15.
Neuropeptide Y-Y2 receptors mediate anxiety in the amygdala.
Pharmacol Biochem Behav
; 71(3): 419-23, 2002 Mar.
Article
in English
| MEDLINE | ID: mdl-11830176
16.
LSN2424100: a novel, potent orexin-2 receptor antagonist with selectivity over orexin-1 receptors and activity in an animal model predictive of antidepressant-like efficacy.
Front Neurosci
; 8: 5, 2014.
Article
in English
| MEDLINE | ID: mdl-24478625
17.
Neuropeptide Y Y4 receptor homodimers dissociate upon agonist stimulation.
J Pharmacol Exp Ther
; 307(3): 1120-6, 2003 Dec.
Article
in English
| MEDLINE | ID: mdl-14551289
18.
The use of bioluminescence resonance energy transfer 2 to study neuropeptide Y receptor agonist-induced beta-arrestin 2 interaction.
J Pharmacol Exp Ther
; 306(1): 147-56, 2003 Jul.
Article
in English
| MEDLINE | ID: mdl-12665544
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