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1.
Orally Bioavailable Macrocyclic Peptide That Inhibits Binding of PCSK9 to the Low Density Lipoprotein Receptor.
Circulation
; 148(2): 144-158, 2023 07 11.
Article
in English
| MEDLINE | ID: mdl-37125593
2.
A drug-drug interaction study with letermovir and acyclovir in healthy participants.
Br J Clin Pharmacol
; 89(5): 1690-1694, 2023 05.
Article
in English
| MEDLINE | ID: mdl-36537620
3.
Evaluation of the inhibitory effects of itraconazole on letermovir.
Br J Clin Pharmacol
; 89(7): 2122-2130, 2023 07.
Article
in English
| MEDLINE | ID: mdl-36717270
4.
Safety and Pharmacokinetics of Islatravir in Individuals with Severe Renal Insufficiency.
Antimicrob Agents Chemother
; 66(12): e0093122, 2022 12 20.
Article
in English
| MEDLINE | ID: mdl-36346229
5.
Pharmacokinetic and Safety Profile of the Novel HIV Nonnucleoside Reverse Transcriptase Inhibitor MK-8507 in Adults without HIV.
Antimicrob Agents Chemother
; 65(12): e0093521, 2021 11 17.
Article
in English
| MEDLINE | ID: mdl-34516246
6.
Pharmacokinetics, safety and tolerability of long-acting parenteral intramuscular injection formulations of doravirine.
J Clin Pharm Ther
; 45(5): 1098-1105, 2020 Oct.
Article
in English
| MEDLINE | ID: mdl-32501541
7.
A phase 1 pooled PK/PD analysis of bone resorption biomarkers for odanacatib, a Cathepsin K inhibitor.
J Pharmacokinet Pharmacodyn
; 47(5): 473-484, 2020 10.
Article
in English
| MEDLINE | ID: mdl-32647957
8.
Comparative Bioavailability of Oral Granule Formulations of the HIV Antiretroviral Drugs Doravirine, Lamivudine, and Tenofovir Disoproxil Fumarate.
AAPS PharmSciTech
; 21(3): 91, 2020 Feb 13.
Article
in English
| MEDLINE | ID: mdl-32060665
9.
Investigation of Pharmacokinetic Interactions between Doravirine and Elbasvir-Grazoprevir and Ledipasvir-Sofosbuvir.
Antimicrob Agents Chemother
; 63(5)2019 05.
Article
in English
| MEDLINE | ID: mdl-30782982
10.
Clinical and translational pharmacology of the cathepsin K inhibitor odanacatib studied for osteoporosis.
Br J Clin Pharmacol
; 85(6): 1072-1083, 2019 06.
Article
in English
| MEDLINE | ID: mdl-30663085
11.
A randomized clinical trial to evaluate the single-dose pharmacokinetics, pharmacodynamics, and safety of sitagliptin in pediatric patients with type 2 diabetes.
Pediatr Diabetes
; 20(1): 48-56, 2019 02.
Article
in English
| MEDLINE | ID: mdl-30346099
12.
Effect of letermovir on levonorgestrel and ethinyl estradiol pharmacokineticsâ©.
Int J Clin Pharmacol Ther
; 57(9): 450-457, 2019 Sep.
Article
in English
| MEDLINE | ID: mdl-31232280
13.
Linearity of ß-cell response across the metabolic spectrum and to pharmacology: insights from a graded glucose infusion-based investigation series.
Am J Physiol Endocrinol Metab
; 310(11): E865-73, 2016 Jun 01.
Article
in English
| MEDLINE | ID: mdl-27072496
14.
The Absolute Bioavailability and Effect of Food on the Pharmacokinetics of Odanacatib: A Stable-Label i.v./Oral Study in Healthy Postmenopausal Women.
Drug Metab Dispos
; 44(9): 1450-8, 2016 09.
Article
in English
| MEDLINE | ID: mdl-27402726
15.
Disposition and metabolism of the cathepsin K inhibitor odanacatib in humans.
Drug Metab Dispos
; 42(5): 818-27, 2014 May.
Article
in English
| MEDLINE | ID: mdl-24553380
16.
Pitavastatin is a more sensitive and selective organic anion-transporting polypeptide 1B clinical probe than rosuvastatin.
Br J Clin Pharmacol
; 78(3): 587-98, 2014 Sep.
Article
in English
| MEDLINE | ID: mdl-24617605
17.
Pooled analysis of routine safety parameters observed in healthy participants at baseline and following placebo administration in early phase clinical studies.
Clin Transl Sci
; 17(1): e13715, 2024 01.
Article
in English
| MEDLINE | ID: mdl-38266056
18.
Phase 1 Study of MK-5475, an Inhaled Soluble Guanylate Cyclase Stimulator, in Participants with Pulmonary Hypertension Associated with Chronic Obstructive Pulmonary Disease.
Int J Chron Obstruct Pulmon Dis
; 19: 1105-1121, 2024.
Article
in English
| MEDLINE | ID: mdl-38803412
19.
Single- and Multiple-Dose Pharmacokinetics of Gefapixant (MK-7264), a P2X3 Receptor Antagonist, in Healthy Adults.
J Clin Pharmacol
; 2024 Apr 23.
Article
in English
| MEDLINE | ID: mdl-38651193
20.
Odanacatib, a selective cathepsin K inhibitor to treat osteoporosis: safety, tolerability, pharmacokinetics and pharmacodynamics--results from single oral dose studies in healthy volunteers.
Br J Clin Pharmacol
; 75(5): 1240-54, 2013 May.
Article
in English
| MEDLINE | ID: mdl-23013236