Search details
1.
Multiple autism-linked genes mediate synapse elimination via proteasomal degradation of a synaptic scaffold PSD-95.
Cell
; 151(7): 1581-94, 2012 Dec 21.
Article
in English
| MEDLINE | ID: mdl-23260144
2.
Hyperfunction of post-synaptic density protein 95 promotes seizure response in early-stage aĆ pathology.
EMBO Rep
; 25(3): 1233-1255, 2024 Mar.
Article
in English
| MEDLINE | ID: mdl-38413732
3.
Tmod2 Is a Regulator of Cocaine Responses through Control of Striatal and Cortical Excitability and Drug-Induced Plasticity.
J Neurosci
; 44(18)2024 May 01.
Article
in English
| MEDLINE | ID: mdl-38508714
4.
Tumor suppressor p53 modulates activity-dependent synapse strengthening, autism-like behavior and hippocampus-dependent learning.
Mol Psychiatry
; 28(9): 3782-3794, 2023 Sep.
Article
in English
| MEDLINE | ID: mdl-37759036
5.
Infantile spasms-linked Nedd4-2 mediates hippocampal plasticity and learning via cofilin signaling.
EMBO Rep
; 22(10): e52645, 2021 10 05.
Article
in English
| MEDLINE | ID: mdl-34342389
6.
Amyloid beta induces Fmr1-dependent translational suppression and hyposynchrony of neural activity via phosphorylation of eIF2α and eEF2.
J Cell Physiol
; 237(7): 2929-2942, 2022 07.
Article
in English
| MEDLINE | ID: mdl-35434801
7.
E3 ubiquitin ligase Nedd4-2 exerts neuroprotective effects during endoplasmic reticulum stress.
J Neurochem
; 160(6): 613-624, 2022 03.
Article
in English
| MEDLINE | ID: mdl-34935153
8.
Novel roles of ER stress in repressing neural activity and seizures through Mdm2- and p53-dependent protein translation.
PLoS Genet
; 15(9): e1008364, 2019 09.
Article
in English
| MEDLINE | ID: mdl-31557161
9.
Unbiased proteomic screening identifies a novel role for the E3 ubiquitin ligase Nedd4-2 in translational suppression during ER stress.
J Neurochem
; 157(6): 1809-1820, 2021 06.
Article
in English
| MEDLINE | ID: mdl-33064840
10.
ER stress-induced modulation of neural activity and seizure susceptibility is impaired in a fragile X syndrome mouse model.
Neurobiol Dis
; 158: 105450, 2021 10.
Article
in English
| MEDLINE | ID: mdl-34303799
11.
Loss of fragile X protein FMRP impairs homeostatic synaptic downscaling through tumor suppressor p53 and ubiquitin E3 ligase Nedd4-2.
Hum Mol Genet
; 27(16): 2805-2816, 2018 08 15.
Article
in English
| MEDLINE | ID: mdl-29771335
12.
Epilepsy-associated gene Nedd4-2 mediates neuronal activity and seizure susceptibility through AMPA receptors.
PLoS Genet
; 13(2): e1006634, 2017 02.
Article
in English
| MEDLINE | ID: mdl-28212375
13.
C2-lacking isoform of Nedd4-2 regulates excitatory synaptic strength through GluA1 ubiquitination-independent mechanisms.
J Neurochem
; 151(3): 289-300, 2019 11.
Article
in English
| MEDLINE | ID: mdl-31357244
14.
FMRP-dependent Mdm2 dephosphorylation is required for MEF2-induced synapse elimination.
Hum Mol Genet
; 26(2): 293-304, 2017 01 15.
Article
in English
| MEDLINE | ID: mdl-28025327
15.
Mdm2 mediates FMRP- and Gp1 mGluR-dependent protein translation and neural network activity.
Hum Mol Genet
; 26(20): 3895-3908, 2017 10 15.
Article
in English
| MEDLINE | ID: mdl-29016848
16.
Reduced axonal surface expression and phosphoinositide sensitivity in Kv7 channels disrupts their function to inhibit neuronal excitability in Kcnq2 epileptic encephalopathy.
Neurobiol Dis
; 118: 76-93, 2018 10.
Article
in English
| MEDLINE | ID: mdl-30008368
17.
Ubiquitin proteasome system-mediated degradation of synaptic proteins: An update from the postsynaptic side.
Biochim Biophys Acta
; 1843(12): 2838-2842, 2014 Dec.
Article
in English
| MEDLINE | ID: mdl-25135362
18.
The tumor suppressor p53 guides GluA1 homeostasis through Nedd4-2 during chronic elevation of neuronal activity.
J Neurochem
; 135(2): 226-33, 2015 Oct.
Article
in English
| MEDLINE | ID: mdl-26250624
19.
mGluR7 allosteric modulator AMN082 corrects protein synthesis and pathological phenotypes in FXS.
EMBO Mol Med
; 16(3): 506-522, 2024 Mar.
Article
in English
| MEDLINE | ID: mdl-38374465
20.
Kappa opioid receptor contributes to EGF-stimulated neurite extension in development.
Proc Natl Acad Sci U S A
; 107(7): 3216-21, 2010 Feb 16.
Article
in English
| MEDLINE | ID: mdl-20133770