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1.
An emerging class of new therapeutics targeting TGF, Activin, and BMP ligands in pulmonary arterial hypertension.
Dev Dyn
; 252(3): 327-342, 2023 03.
Article
in English
| MEDLINE | ID: mdl-35434863
2.
First Genotype-Phenotype Study in TBX4 Syndrome: Gain-of-Function Mutations Causative for Lung Disease.
Am J Respir Crit Care Med
; 206(12): 1522-1533, 2022 12 15.
Article
in English
| MEDLINE | ID: mdl-35852389
3.
Endothelial protective factors BMP9 and BMP10 inhibit CCL2 release by human vascular endothelial cells.
J Cell Sci
; 133(14)2020 07 21.
Article
in English
| MEDLINE | ID: mdl-32576665
4.
Circulating BMP9 Protects the Pulmonary Endothelium during Inflammation-induced Lung Injury in Mice.
Am J Respir Crit Care Med
; 203(11): 1419-1430, 2021 06 01.
Article
in English
| MEDLINE | ID: mdl-33320799
5.
Generation of a Soluble Form of Human Endoglin Fused to Green Fluorescent Protein.
Int J Mol Sci
; 22(20)2021 Oct 19.
Article
in English
| MEDLINE | ID: mdl-34681942
6.
4PBA Restores Signaling of a Cysteine-substituted Mutant BMPR2 Receptor Found in Patients with Pulmonary Arterial Hypertension.
Am J Respir Cell Mol Biol
; 63(2): 160-171, 2020 08.
Article
in English
| MEDLINE | ID: mdl-32255665
7.
Bone Morphogenetic Protein 9 Is a Mechanistic Biomarker of Portopulmonary Hypertension.
Am J Respir Crit Care Med
; 199(7): 891-902, 2019 04 01.
Article
in English
| MEDLINE | ID: mdl-30312106
8.
Bone morphogenetic protein 9 (BMP9) and BMP10 enhance tumor necrosis factor-α-induced monocyte recruitment to the vascular endothelium mainly via activin receptor-like kinase 2.
J Biol Chem
; 292(33): 13714-13726, 2017 08 18.
Article
in English
| MEDLINE | ID: mdl-28646109
9.
Elabela/Toddler Is an Endogenous Agonist of the Apelin APJ Receptor in the Adult Cardiovascular System, and Exogenous Administration of the Peptide Compensates for the Downregulation of Its Expression in Pulmonary Arterial Hypertension.
Circulation
; 135(12): 1160-1173, 2017 Mar 21.
Article
in English
| MEDLINE | ID: mdl-28137936
10.
Identification of MicroRNA-124 as a Major Regulator of Enhanced Endothelial Cell Glycolysis in Pulmonary Arterial Hypertension via PTBP1 (Polypyrimidine Tract Binding Protein) and Pyruvate Kinase M2.
Circulation
; 136(25): 2451-2467, 2017 Dec 19.
Article
in English
| MEDLINE | ID: mdl-28971999
11.
A 3D tri-culture system reveals that activin receptor-like kinase 5 and connective tissue growth factor drive human glomerulosclerosis.
J Pathol
; 243(3): 390-400, 2017 11.
Article
in English
| MEDLINE | ID: mdl-28815607
12.
Bone Morphogenetic Protein 9 Enhances Lipopolysaccharide-Induced Leukocyte Recruitment to the Vascular Endothelium.
J Immunol
; 197(8): 3302-3314, 2016 10 15.
Article
in English
| MEDLINE | ID: mdl-27647829
13.
The Prodomain-bound Form of Bone Morphogenetic Protein 10 Is Biologically Active on Endothelial Cells.
J Biol Chem
; 291(6): 2954-66, 2016 Feb 05.
Article
in English
| MEDLINE | ID: mdl-26631724
14.
BMP9 mutations cause a vascular-anomaly syndrome with phenotypic overlap with hereditary hemorrhagic telangiectasia.
Am J Hum Genet
; 93(3): 530-7, 2013 Sep 05.
Article
in English
| MEDLINE | ID: mdl-23972370
15.
Circulating Bmp10 acts through endothelial Alk1 to mediate flow-dependent arterial quiescence.
Development
; 140(16): 3403-12, 2013 Aug.
Article
in English
| MEDLINE | ID: mdl-23863480
16.
Letter by Morrell et al Regarding Article, "Selective BMP-9 Inhibition Partially Protects Against Experimental Pulmonary Hypertension".
Circ Res
; 124(9): e81, 2019 04 26.
Article
in English
| MEDLINE | ID: mdl-31021722
17.
Regulation of bone morphogenetic protein 9 (BMP9) by redox-dependent proteolysis.
J Biol Chem
; 289(45): 31150-9, 2014 Nov 07.
Article
in English
| MEDLINE | ID: mdl-25237187
18.
The lysosomal inhibitor, chloroquine, increases cell surface BMPR-II levels and restores BMP9 signalling in endothelial cells harbouring BMPR-II mutations.
Hum Mol Genet
; 22(18): 3667-79, 2013 Sep 15.
Article
in English
| MEDLINE | ID: mdl-23669347
19.
Connexin-mediated regulation of the pulmonary vasculature.
Biochem Soc Trans
; 43(3): 524-9, 2015 Jun.
Article
in English
| MEDLINE | ID: mdl-26009202
20.
SEMA3G regulates BMP9 inhibition of VEGF-mediated migration and network formation in pulmonary endothelial cells.
Vascul Pharmacol
; 155: 107381, 2024 May 23.
Article
in English
| MEDLINE | ID: mdl-38795838