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1.
Pan-KRAS inhibitor disables oncogenic signalling and tumour growth.
Nature
; 619(7968): 160-166, 2023 Jul.
Article
in English
| MEDLINE | ID: mdl-37258666
2.
HUWE1 employs a giant substrate-binding ring to feed and regulate its HECT E3 domain.
Nat Chem Biol
; 17(10): 1084-1092, 2021 10.
Article
in English
| MEDLINE | ID: mdl-34294896
3.
Drugging an undruggable pocket on KRAS.
Proc Natl Acad Sci U S A
; 116(32): 15823-15829, 2019 08 06.
Article
in English
| MEDLINE | ID: mdl-31332011
4.
PI by NMR: Probing CH-π Interactions in Protein-Ligand Complexes by NMR Spectroscopy.
Angew Chem Int Ed Engl
; 59(35): 14861-14868, 2020 08 24.
Article
in English
| MEDLINE | ID: mdl-32421895
5.
KRAS Binders Hidden in Nature.
Chemistry
; 25(52): 12037-12041, 2019 Sep 18.
Article
in English
| MEDLINE | ID: mdl-31231840
6.
Reply to Tran et al.: Dimeric KRAS protein-protein interaction stabilizers.
Proc Natl Acad Sci U S A
; 117(7): 3365-3367, 2020 02 18.
Article
in English
| MEDLINE | ID: mdl-32047042
7.
Discovery of a Chemical Probe to Study Implications of BPTF Bromodomain Inhibition in Cellular and inâ vivo Experiments.
ChemMedChem
; 18(6): e202200686, 2023 03 14.
Article
in English
| MEDLINE | ID: mdl-36649575
8.
Getting a Grip on the Undrugged: Targeting ß-Catenin with Fragment-Based Methods.
ChemMedChem
; 16(9): 1420-1424, 2021 05 06.
Article
in English
| MEDLINE | ID: mdl-33275320
9.
One Atom Makes All the Difference: Getting a Foot in the Door between SOS1 and KRAS.
J Med Chem
; 64(10): 6569-6580, 2021 05 27.
Article
in English
| MEDLINE | ID: mdl-33719426
10.
Intracellular Trapping of the Selective Phosphoglycerate Dehydrogenase (PHGDH) Inhibitor BI-4924 Disrupts Serine Biosynthesis.
J Med Chem
; 62(17): 7976-7997, 2019 09 12.
Article
in English
| MEDLINE | ID: mdl-31365252
11.
Direct NMR Probing of Hydration Shells of Protein Ligand Interfaces and Its Application to Drug Design.
J Med Chem
; 60(21): 8708-8715, 2017 11 09.
Article
in English
| MEDLINE | ID: mdl-28910100
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