Search details
1.
Phenoxyacetic acids as PPARδ partial agonists: synthesis, optimization, and in vivo efficacy.
Bioorg Med Chem Lett
; 21(8): 2345-50, 2011 Apr 15.
Article
in English
| MEDLINE | ID: mdl-21414782
2.
Discovery of GSK1997132B a novel centrally penetrant benzimidazole PPARγ partial agonist.
Bioorg Med Chem Lett
; 21(18): 5568-72, 2011 Sep 15.
Article
in English
| MEDLINE | ID: mdl-21798739
3.
Discovery of a novel class of PPARdelta partial agonists.
Bioorg Med Chem Lett
; 18(18): 5018-22, 2008 Sep 15.
Article
in English
| MEDLINE | ID: mdl-18722772
4.
Substituted 2-[(4-aminomethyl)phenoxy]-2-methylpropionic acid PPARalpha agonists. 1. Discovery of a novel series of potent HDLc raising agents.
J Med Chem
; 50(4): 685-95, 2007 Feb 22.
Article
in English
| MEDLINE | ID: mdl-17243659
5.
Crystal structures of the catalytic domain of phosphodiesterase 4B complexed with AMP, 8-Br-AMP, and rolipram.
J Mol Biol
; 337(2): 355-65, 2004 Mar 19.
Article
in English
| MEDLINE | ID: mdl-15003452
6.
Crystallization of cyclic nucleotide phosphodiesterases.
Methods Mol Biol
; 307: 181-90, 2005.
Article
in English
| MEDLINE | ID: mdl-15988064
7.
Identification and characterization of 4-chloro-N-(2-{[5-trifluoromethyl)-2-pyridyl]sulfonyl}ethyl)benzamide (GSK3787), a selective and irreversible peroxisome proliferator-activated receptor delta (PPARdelta) antagonist.
J Med Chem
; 53(4): 1857-61, 2010 Feb 25.
Article
in English
| MEDLINE | ID: mdl-20128594
8.
Ultra-potent P1 modified arylsulfonamide HIV protease inhibitors: the discovery of GW0385.
Bioorg Med Chem Lett
; 16(7): 1788-94, 2006 Apr 01.
Article
in English
| MEDLINE | ID: mdl-16458505
9.
Structural analyses reveal phosphatidyl inositols as ligands for the NR5 orphan receptors SF-1 and LRH-1.
Cell
; 120(3): 343-55, 2005 Feb 11.
Article
in English
| MEDLINE | ID: mdl-15707893
10.
A structural basis for constitutive activity in the human CAR/RXRalpha heterodimer.
Mol Cell
; 16(6): 919-28, 2004 Dec 22.
Article
in English
| MEDLINE | ID: mdl-15610735
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