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1.
Mouse Fkbp8 activity is required to inhibit cell death and establish dorso-ventral patterning in the posterior neural tube.
Hum Mol Genet
; 17(4): 587-601, 2008 Feb 15.
Article
in English
| MEDLINE | ID: mdl-18003640
2.
GPIHBP1 stabilizes lipoprotein lipase and prevents its inhibition by angiopoietin-like 3 and angiopoietin-like 4.
J Lipid Res
; 50(12): 2421-9, 2009 Dec.
Article
in English
| MEDLINE | ID: mdl-19542565
3.
Knockouts model the 100 best-selling drugs--will they model the next 100?
Nat Rev Drug Discov
; 2(1): 38-51, 2003 01.
Article
in English
| MEDLINE | ID: mdl-12509758
4.
mdmx is a negative regulator of p53 activity in vivo.
Cancer Res
; 62(11): 3221-5, 2002 Jun 01.
Article
in English
| MEDLINE | ID: mdl-12036937
5.
Predicting drug efficacy: knockouts model pipeline drugs of the pharmaceutical industry.
Curr Opin Pharmacol
; 3(5): 563-70, 2003 Oct.
Article
in English
| MEDLINE | ID: mdl-14559104
6.
Sotagliflozin, a Dual SGLT1 and SGLT2 Inhibitor, as Adjunct Therapy to Insulin in Type 1 Diabetes.
Diabetes Care
; 38(7): 1181-8, 2015 Jul.
Article
in English
| MEDLINE | ID: mdl-26049551
7.
Full-speed mammalian genetics: in vivo target validation in the drug discovery process.
Trends Biotechnol
; 20(1): 36-42, 2002 Jan.
Article
in English
| MEDLINE | ID: mdl-11742676
8.
Severe retinal degeneration associated with disruption of semaphorin 4A.
Invest Ophthalmol Vis Sci
; 45(8): 2767-77, 2004 Aug.
Article
in English
| MEDLINE | ID: mdl-15277503
9.
Genetic deletion of Mst1 alters T cell function and protects against autoimmunity.
PLoS One
; 9(5): e98151, 2014.
Article
in English
| MEDLINE | ID: mdl-24852423
10.
Keratinocyte migration in the developing eyelid requires LIMK2.
PLoS One
; 7(10): e47168, 2012.
Article
in English
| MEDLINE | ID: mdl-23071748
11.
A mouse knockout library for secreted and transmembrane proteins.
Nat Biotechnol
; 28(7): 749-55, 2010 Jul.
Article
in English
| MEDLINE | ID: mdl-20562862
12.
Identification of a new functional domain in angiopoietin-like 3 (ANGPTL3) and angiopoietin-like 4 (ANGPTL4) involved in binding and inhibition of lipoprotein lipase (LPL).
J Biol Chem
; 284(20): 13735-13745, 2009 May 15.
Article
in English
| MEDLINE | ID: mdl-19318355
13.
Large-scale gene trapping in C57BL/6N mouse embryonic stem cells.
Genome Res
; 18(10): 1670-9, 2008 Oct.
Article
in English
| MEDLINE | ID: mdl-18799693
14.
High-throughput screening of mouse knockout lines identifies true lean and obese phenotypes.
Obesity (Silver Spring)
; 16(10): 2362-7, 2008 Oct.
Article
in English
| MEDLINE | ID: mdl-18719666
15.
Lipid-lowering effects of anti-angiopoietin-like 4 antibody recapitulate the lipid phenotype found in angiopoietin-like 4 knockout mice.
Proc Natl Acad Sci U S A
; 104(28): 11766-71, 2007 Jul 10.
Article
in English
| MEDLINE | ID: mdl-17609370
16.
Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Proc Natl Acad Sci U S A
; 100(24): 14109-14, 2003 Nov 25.
Article
in English
| MEDLINE | ID: mdl-14610273
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