Search details
1.
Phase Separation of Disease-Associated SHP2 Mutants Underlies MAPK Hyperactivation.
Cell
; 183(2): 490-502.e18, 2020 10 15.
Article
in English
| MEDLINE | ID: mdl-33002410
2.
Leptin and insulin act on POMC neurons to promote the browning of white fat.
Cell
; 160(1-2): 88-104, 2015 Jan 15.
Article
in English
| MEDLINE | ID: mdl-25594176
3.
PTPN9 dephosphorylates FGFR2 pY656/657 through interaction with ACAP1 and ameliorates pemigatinib effect in cholangiocarcinoma.
Hepatology
; 79(4): 798-812, 2024 Apr 01.
Article
in English
| MEDLINE | ID: mdl-37505213
4.
PRL2 phosphatase enhances oncogenic FLT3 signaling via dephosphorylation of the E3 ubiquitin ligase CBL at tyrosine 371.
Blood
; 141(3): 244-259, 2023 01 19.
Article
in English
| MEDLINE | ID: mdl-36206490
5.
PTPN2 phosphatase deletion in T cells promotes anti-tumour immunity and CAR T-cell efficacy in solid tumours.
EMBO J
; 39(2): e103637, 2020 01 15.
Article
in English
| MEDLINE | ID: mdl-31803974
6.
Discovery of flavone-derivatives as the new skeleton of transient receptor potential vanilloid 3 channel antagonists.
Bioorg Med Chem Lett
; 98: 129577, 2024 Jan 15.
Article
in English
| MEDLINE | ID: mdl-38065293
7.
Natural Product-Inspired Molecules for Covalent Inhibition of SHP2 Tyrosine Phosphatase.
Tetrahedron
; 1562024 Apr 28.
Article
in English
| MEDLINE | ID: mdl-38618612
8.
Lattice dynamics and heat transport in zeolitic imidazolate framework glasses.
J Chem Phys
; 160(12)2024 Mar 28.
Article
in English
| MEDLINE | ID: mdl-38545950
9.
The Toxoplasma glucan phosphatase TgLaforin utilizes a distinct functional mechanism that can be exploited by therapeutic inhibitors.
J Biol Chem
; 298(7): 102089, 2022 07.
Article
in English
| MEDLINE | ID: mdl-35640720
10.
Nano-DESI Mass Spectrometry Imaging of Proteoforms in Biological Tissues with High Spatial Resolution.
Anal Chem
; 95(12): 5214-5222, 2023 03 28.
Article
in English
| MEDLINE | ID: mdl-36917636
11.
PTP-MEG2 regulates quantal size and fusion pore opening through two distinct structural bases and substrates.
EMBO Rep
; 22(5): e52141, 2021 05 05.
Article
in English
| MEDLINE | ID: mdl-33764618
12.
Laminarin Reduces Cholesterol Uptake and NPC1L1 Protein Expression in High-Fat Diet (HFD)-Fed Mice.
Mar Drugs
; 21(12)2023 Nov 29.
Article
in English
| MEDLINE | ID: mdl-38132943
13.
Mechanism of PRL2 phosphatase-mediated PTEN degradation and tumorigenesis.
Proc Natl Acad Sci U S A
; 117(34): 20538-20548, 2020 08 25.
Article
in English
| MEDLINE | ID: mdl-32788364
14.
Discovery of a SHP2 Degrader with In Vivo Anti-Tumor Activity.
Molecules
; 28(19)2023 Oct 06.
Article
in English
| MEDLINE | ID: mdl-37836790
15.
Small Molecule Degraders of Protein Tyrosine Phosphatase 1B and T-Cell Protein Tyrosine Phosphatase for Cancer Immunotherapy.
Angew Chem Int Ed Engl
; 62(22): e202303818, 2023 05 22.
Article
in English
| MEDLINE | ID: mdl-36973833
16.
An Integrated Proteomic Strategy to Identify SHP2 Substrates.
J Proteome Res
; 21(10): 2515-2525, 2022 Oct 07.
Article
in English
| MEDLINE | ID: mdl-36103635
17.
Mechanistic insights explain the transforming potential of the T507K substitution in the protein-tyrosine phosphatase SHP2.
J Biol Chem
; 295(18): 6187-6201, 2020 05 01.
Article
in English
| MEDLINE | ID: mdl-32188694
18.
Functional interrogation and therapeutic targeting of protein tyrosine phosphatases.
Biochem Soc Trans
; 49(4): 1723-1734, 2021 08 27.
Article
in English
| MEDLINE | ID: mdl-34431504
19.
The design and synthesis of transient receptor potential vanilloid 3 inhibitors with novel skeleton.
Bioorg Chem
; 114: 105115, 2021 09.
Article
in English
| MEDLINE | ID: mdl-34175725
20.
A simple strategy for the detection of Pb(II) and Cu(II) by an electrochemical sensor based on Zn/Ni-ZIF-8/XC-72/Nafion hybrid materials.
Environ Res
; 202: 111605, 2021 11.
Article
in English
| MEDLINE | ID: mdl-34197819