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1.
A phase 2 trial investigating the efficacy and safety of the mPGES-1 inhibitor vipoglanstat in systemic sclerosis-related Raynaud's.
Rheumatology (Oxford)
; 2024 Jan 30.
Artículo
en Inglés
| MEDLINE | ID: mdl-38291895
2.
Nonclinical and clinical pharmacological characterization of the potent and selective cathepsin K inhibitor MIV-711.
J Transl Med
; 16(1): 125, 2018 05 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-29743078
3.
The selective cathepsin K inhibitor MIV-711 attenuates joint pathology in experimental animal models of osteoarthritis.
J Transl Med
; 16(1): 56, 2018 03 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-29523155
4.
Selective Cathepsin S Inhibition with MIV-247 Attenuates Mechanical Allodynia and Enhances the Antiallodynic Effects of Gabapentin and Pregabalin in a Mouse Model of Neuropathic Pain.
J Pharmacol Exp Ther
; 358(3): 387-96, 2016 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-27335437
5.
The influence of aspirin on release of eoxin C4, leukotriene C4 and 15-HETE, in eosinophilic granulocytes isolated from patients with asthma.
Int Arch Allergy Immunol
; 162(2): 135-42, 2013.
Artículo
en Inglés
| MEDLINE | ID: mdl-23921438
6.
Eoxins are proinflammatory arachidonic acid metabolites produced via the 15-lipoxygenase-1 pathway in human eosinophils and mast cells.
Proc Natl Acad Sci U S A
; 105(2): 680-5, 2008 Jan 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-18184802
7.
Population pharmacokinetic modelling and estimation of dosing strategy for NXY-059, a nitrone being developed for stroke.
Clin Pharmacokinet
; 44(8): 863-78, 2005.
Artículo
en Inglés
| MEDLINE | ID: mdl-16029070
8.
Pharmacokinetics of NXY-059, a nitrone-based free radical trapping agent, in healthy young and elderly subjects.
J Stroke Cerebrovasc Dis
; 11(1): 34-42, 2002.
Artículo
en Inglés
| MEDLINE | ID: mdl-17903853
9.
Sublingual zolpidem in early onset of sleep compared to oral zolpidem: polysomnographic study in patients with primary insomnia.
Curr Med Res Opin
; 26(6): 1423-31, 2010 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-20397964
10.
Pharmacokinetic/pharmacodynamic models for the depletion of Vbeta5.2/5.3 T cells by the monoclonal antibody ATM-027 in patients with multiple sclerosis, as measured by FACS.
Br J Clin Pharmacol
; 58(4): 378-89, 2004 Oct.
Artículo
en Inglés
| MEDLINE | ID: mdl-15373930
11.
Pharmacokinetics in renally impaired subjects of NXY-059, a nitrone-based, free-radical trapping agent developed for the treatment of acute stroke.
Eur J Clin Pharmacol
; 58(6): 409-15, 2002 Sep.
Artículo
en Inglés
| MEDLINE | ID: mdl-12242600
12.
Antibody-mediated suppression of Vbeta5.2/5.3(+) T cells in multiple sclerosis: results from an MRI-monitored phase II clinical trial.
Ann Neurol
; 51(4): 467-74, 2002 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-11921052
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