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1.
Development of IFNß-1a versions with reduced immunogenicity and full in vitro biological activity for the treatment of multiple sclerosis.
Clin Immunol
; 257: 109831, 2023 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-37931868
2.
Development of highly stable and de-immunized versions of recombinant alpha interferon: Promising candidates for the treatment of chronic and emerging viral diseases.
Clin Immunol
; 233: 108888, 2021 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-34798238
3.
Pharmacokinetics Versus In Vitro Antiproliferative Potency to Design a Novel Hyperglycosylated hIFN-α2 Biobetter.
Pharm Res
; 38(1): 37-50, 2021 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-33443683
4.
Development of Magoh protein-overexpressing HEK cells for optimized therapeutic protein production.
Biotechnol Appl Biochem
; 68(2): 230-238, 2021 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-32249976
5.
The glycosylation of anti-rhIFN-α2b recombinant antibodies influences the antigen-neutralizing activity.
Biotechnol Lett
; 42(8): 1369-1381, 2020 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-32285235
6.
Production of Therapeutic Enzymes by Lentivirus Transgenesis.
Adv Exp Med Biol
; 1148: 25-54, 2019.
Artículo
en Inglés
| MEDLINE | ID: mdl-31482493
7.
De-immunized and Functional Therapeutic (DeFT) versions of a long lasting recombinant alpha interferon for antiviral therapy.
Clin Immunol
; 176: 31-41, 2017 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-28089609
8.
A highly efficient modified human serum albumin signal peptide to secrete proteins in cells derived from different mammalian species.
Protein Expr Purif
; 132: 27-33, 2017 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-28089882
9.
Development of lentiviral vectors for transient and stable protein overexpression in mammalian cells. A new strategy for recombinant human FVIII (rhFVIII) production.
Protein Expr Purif
; 95: 50-6, 2014 Mar.
Artículo
en Inglés
| MEDLINE | ID: mdl-24275638
10.
A versatile ionic strength sensitive tag from a human GM-CSF-derived linear epitope.
Protein Expr Purif
; 91(1): 10-9, 2013 Sep.
Artículo
en Inglés
| MEDLINE | ID: mdl-23800752
11.
Specific sequence mutations in a long-lasting rhIFN-α2b version reduce in vitro and in vivo immunogenicity and increase in vitro protein stability.
Heliyon
; 9(3): e14670, 2023 Mar.
Artículo
en Inglés
| MEDLINE | ID: mdl-37020947
12.
Development, Production, and Characterization of Hepatitis B Subviral Envelope Particles as a Third-Generation Vaccine.
Methods Mol Biol
; 2410: 273-287, 2022.
Artículo
en Inglés
| MEDLINE | ID: mdl-34914052
13.
Rabies VLPs adjuvanted with saponin-based liposomes induce enhanced immunogenicity mediated by neutralizing antibodies in cattle, dogs and cats.
J Virol Methods
; 286: 113966, 2020 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-32905818
14.
Characterization of hepatitis B virus surface antigen particles expressed in stably transformed mammalian cell lines containing the large, middle and small surface protein.
Antiviral Res
; 183: 104936, 2020 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-32979402
15.
Design and validation of an immuno-PCR assay for IFN-α2b quantification in human plasma.
Bioanalysis
; 11(23): 2175-2188, 2019 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-31724446
16.
A simplified roller bottle platform for the production of a new generation VLPs rabies vaccine for veterinary applications.
Comp Immunol Microbiol Infect Dis
; 65: 70-75, 2019 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-31300130
17.
Multiplexed Gene Expression as a Characterization of Bioactivity for Interferon Beta (IFN-ß) Biosimilar Candidates: Impact of Innate Immune Response Modulating Impurities (IIRMIs).
AAPS J
; 21(2): 26, 2019 02 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-30737590
18.
Strategies to Develop Therapeutic N- and O-Hyperglycosylated Proteins.
Methods Mol Biol
; 1674: 163-181, 2018.
Artículo
en Inglés
| MEDLINE | ID: mdl-28921436
19.
Strategy for erythroid differentiation in ex vivo cultures: Lentiviral genetic modification of human hematopoietic stem cells with erythropoietin gene.
J Biosci Bioeng
; 124(5): 591-598, 2017 Nov.
Artículo
en Inglés
| MEDLINE | ID: mdl-28688754
20.
An unusual cysteine VL87 affects the antibody fragment conformations without interfering with the disulfide bond formation.
Mol Immunol
; 90: 143-149, 2017 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-28755586