Detalles de la búsqueda
1.
GATA3 (GATA-Binding Protein 3)/KMT2A (Lysine-Methyltransferase-2A) Complex by Increasing H3K4-3me (Trimethylated Lysine-4 of Histone-3) Upregulates NCX3 (Na+-Ca2+ Exchanger 3) Transcription and Contributes to Ischemic Preconditioning Neuroprotection.
Stroke
; 52(11): 3680-3691, 2021 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-34694864
2.
Prolonged NCX activation prevents SOD1 accumulation, reduces neuroinflammation, ameliorates motor behavior and prolongs survival in a ALS mouse model.
Neurobiol Dis
; 159: 105480, 2021 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-34411705
3.
miR-206 Reduces the Severity of Motor Neuron Degeneration in the Facial Nuclei of the Brainstem in a Mouse Model of SMA.
Mol Ther
; 28(4): 1154-1166, 2020 04 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-32075715
4.
Sp3/REST/HDAC1/HDAC2 Complex Represses and Sp1/HIF-1/p300 Complex Activates ncx1 Gene Transcription, in Brain Ischemia and in Ischemic Brain Preconditioning, by Epigenetic Mechanism.
J Neurosci
; 35(19): 7332-48, 2015 May 13.
Artículo
en Inglés
| MEDLINE | ID: mdl-25972164
5.
Extracellular signal-related kinase 2/specificity protein 1/specificity protein 3/repressor element-1 silencing transcription factor pathway is involved in Aroclor 1254-induced toxicity in SH-SY5Y neuronal cells.
J Neurosci Res
; 93(1): 167-77, 2015 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-25093670
6.
MS-275 inhibits aroclor 1254-induced SH-SY5Y neuronal cell toxicity by preventing the formation of the HDAC3/REST complex on the synapsin-1 promoter.
J Pharmacol Exp Ther
; 352(2): 236-43, 2015 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-25467131
7.
Resveratrol via sirtuin-1 downregulates RE1-silencing transcription factor (REST) expression preventing PCB-95-induced neuronal cell death.
Toxicol Appl Pharmacol
; 288(3): 387-98, 2015 Nov 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-26307266
8.
MicroRNA-103-1 selectively downregulates brain NCX1 and its inhibition by anti-miRNA ameliorates stroke damage and neurological deficits.
Mol Ther
; 22(10): 1829-38, 2014 Oct.
Artículo
en Inglés
| MEDLINE | ID: mdl-24954474
9.
Histone deacetylase 4 promotes ubiquitin-dependent proteasomal degradation of Sp3 in SH-SY5Y cells treated with di(2-ethylhexyl)phthalate (DEHP), determining neuronal death.
Toxicol Appl Pharmacol
; 280(1): 190-8, 2014 Oct 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-25068794
10.
Stroke Causes DNA Methylation at Ncx1 Heart Promoter in the Brain Via DNMT1/MeCP2/REST Epigenetic Complex.
J Am Heart Assoc
; 13(6): e030460, 2024 Mar 19.
Artículo
en Inglés
| MEDLINE | ID: mdl-38456444
11.
NCX1 is a new rest target gene: role in cerebral ischemia.
Neurobiol Dis
; 50: 76-85, 2013 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-23069678
12.
New roles of NCX in glial cells: activation of microglia in ischemia and differentiation of oligodendrocytes.
Adv Exp Med Biol
; 961: 307-16, 2013.
Artículo
en Inglés
| MEDLINE | ID: mdl-23224890
13.
Stroke by inducing HDAC9-dependent deacetylation of HIF-1 and Sp1, promotes TfR1 transcription and GPX4 reduction, thus determining ferroptotic neuronal death.
Int J Biol Sci
; 19(9): 2695-2710, 2023.
Artículo
en Inglés
| MEDLINE | ID: mdl-37324938
14.
ERK1/2, p38, and JNK regulate the expression and the activity of the three isoforms of the Na+ /Ca2+ exchanger, NCX1, NCX2, and NCX3, in neuronal PC12 cells.
J Neurochem
; 122(5): 911-22, 2012 Sep.
Artículo
en Inglés
| MEDLINE | ID: mdl-22708976
15.
Identification and characterization of the promoter and transcription factors regulating the expression of cerebral sodium/calcium exchanger 2 (NCX2) gene.
Cell Calcium
; 102: 102542, 2022 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-35114589
16.
The repressor element 1-silencing transcription factor is a novel molecular target for the neurotoxic effect of the polychlorinated biphenyl mixture aroclor 1254 in neuroblastoma SH-SY5Y cells.
J Pharmacol Exp Ther
; 338(3): 997-1003, 2011 Sep.
Artículo
en Inglés
| MEDLINE | ID: mdl-21693630
17.
The Transcriptional Complex Sp1/KMT2A by Up-Regulating Restrictive Element 1 Silencing Transcription Factor Accelerates Methylmercury-Induced Cell Death in Motor Neuron-Like NSC34 Cells Overexpressing SOD1-G93A.
Front Neurosci
; 15: 771580, 2021.
Artículo
en Inglés
| MEDLINE | ID: mdl-34899171
18.
Transcriptional and epigenetic regulation of ncx1 and ncx3 in the brain.
Cell Calcium
; 87: 102194, 2020 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-32172011
19.
HDAC4 and HDAC5 form a complex with DREAM that epigenetically down-regulates NCX3 gene and its pharmacological inhibition reduces neuronal stroke damage.
J Cereb Blood Flow Metab
; 40(10): 2081-2097, 2020 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-31696766
20.
Anti-miR-223-5p Ameliorates Ischemic Damage and Improves Neurological Function by Preventing NCKX2 Downregulation after Ischemia in Rats.
Mol Ther Nucleic Acids
; 18: 1063-1071, 2019 Dec 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-31791013