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1.
Clinical efficacy of a RAF inhibitor needs broad target blockade in BRAF-mutant melanoma.
Nature
; 467(7315): 596-9, 2010 Sep 30.
Artículo
en Inglés
| MEDLINE | ID: mdl-20823850
2.
A novel approach to determine solid fraction using a laser-based direct volume measurement device.
Pharm Dev Technol
; 19(5): 577-82, 2014 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-23930891
3.
The impact of roller compaction and tablet compression on physicomechanical properties of pharmaceutical excipients.
Pharm Dev Technol
; 19(5): 583-92, 2014 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-23941645
4.
Amorphous Solid Dispersions (ASDs): The Influence of Material Properties, Manufacturing Processes and Analytical Technologies in Drug Product Development.
Pharmaceutics
; 13(10)2021 Oct 14.
Artículo
en Inglés
| MEDLINE | ID: mdl-34683975
5.
Design and Discovery of N-(3-(2-(2-Hydroxyethoxy)-6-morpholinopyridin-4-yl)-4-methylphenyl)-2-(trifluoromethyl)isonicotinamide, a Selective, Efficacious, and Well-Tolerated RAF Inhibitor Targeting RAS Mutant Cancers: The Path to the Clinic.
J Med Chem
; 63(5): 2013-2027, 2020 03 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-31059256
6.
Characterization of physico-mechanical properties of indomethacin and polymers to assess their suitability for hot-melt extrusion processs as a means to manufacture solid dispersion/solution.
J Pharm Sci
; 94(11): 2463-74, 2005 Nov.
Artículo
en Inglés
| MEDLINE | ID: mdl-16200544
7.
Antioxidant activity of Syzygium cumini leaf gall extracts.
Bioimpacts
; 4(2): 101-7, 2014.
Artículo
en Inglés
| MEDLINE | ID: mdl-25035854
8.
Stability assessment of hypromellose acetate succinate (HPMCAS) NF for application in hot melt extrusion (HME).
Carbohydr Polym
; 101: 146-53, 2014 Jan 30.
Artículo
en Inglés
| MEDLINE | ID: mdl-24299759
9.
The impact of hot melt extrusion and spray drying on mechanical properties and tableting indices of materials used in pharmaceutical development.
J Pharm Sci
; 102(10): 3604-13, 2013 Oct.
Artículo
en Inglés
| MEDLINE | ID: mdl-23955277
10.
Improved human bioavailability of vemurafenib, a practically insoluble drug, using an amorphous polymer-stabilized solid dispersion prepared by a solvent-controlled coprecipitation process.
J Pharm Sci
; 102(3): 967-81, 2013 Mar.
Artículo
en Inglés
| MEDLINE | ID: mdl-23280631
11.
Development of novel microprecipitated bulk powder (MBP) technology for manufacturing stable amorphous formulations of poorly soluble drugs.
Int J Pharm
; 438(1-2): 53-60, 2012 Nov 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-22974525
12.
RG7204 (PLX4032), a selective BRAFV600E inhibitor, displays potent antitumor activity in preclinical melanoma models.
Cancer Res
; 70(13): 5518-27, 2010 Jul 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-20551065
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