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1.
The development of highly potent and selective small molecule correctors of Z α1-antitrypsin misfolding.
Bioorg Med Chem Lett
; 41: 127973, 2021 06 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-33753261
2.
Utility of drug depletion-time profiles in isolated hepatocytes for accessing hepatic uptake clearance: identifying rate-limiting steps and role of passive processes.
Drug Metab Dispos
; 40(8): 1596-602, 2012 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-22593038
3.
Development of a small molecule that corrects misfolding and increases secretion of Z α1 -antitrypsin.
EMBO Mol Med
; 13(3): e13167, 2021 03 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-33512066
4.
Synthesis and Evaluation of Bicyclic Hydroxypyridones as Inhibitors of Catechol O-Methyltransferase.
ACS Med Chem Lett
; 10(11): 1573-1578, 2019 Nov 14.
Artículo
en Inglés
| MEDLINE | ID: mdl-32038769
5.
Discovery and Lead-Optimization of 4,5-Dihydropyrazoles as Mono-Kinase Selective, Orally Bioavailable and Efficacious Inhibitors of Receptor Interacting Protein 1 (RIP1) Kinase.
J Med Chem
; 62(10): 5096-5110, 2019 05 23.
Artículo
en Inglés
| MEDLINE | ID: mdl-31013427
6.
Optimization of 8-Hydroxyquinolines as Inhibitors of Catechol O-Methyltransferase.
J Med Chem
; 61(21): 9647-9665, 2018 11 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-30272964
7.
Functional expression of sinusoidal and canalicular hepatic drug transporters in the differentiated human hepatoma HepaRG cell line.
Eur J Pharm Sci
; 28(1-2): 109-17, 2006 May.
Artículo
en Inglés
| MEDLINE | ID: mdl-16488578
8.
Physiological, pharmacological and clinical features of the multidrug resistance protein 2.
Biomed Pharmacother
; 59(3): 104-14, 2005 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-15795103
9.
Binding mode and structure-activity relationships around direct inhibitors of the Nrf2-Keap1 complex.
ChemMedChem
; 9(4): 699-705, 2014 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-24504667
10.
Differential regulation of sinusoidal and canalicular hepatic drug transporter expression by xenobiotics activating drug-sensing receptors in primary human hepatocytes.
Drug Metab Dispos
; 34(10): 1756-63, 2006 Oct.
Artículo
en Inglés
| MEDLINE | ID: mdl-16837569
11.
Functional expression of sinusoidal drug transporters in primary human and rat hepatocytes.
Drug Metab Dispos
; 33(10): 1418-22, 2005 Oct.
Artículo
en Inglés
| MEDLINE | ID: mdl-16014767
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