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1.
Tuning mTORC1 activity dictates the response of acute myeloid leukemia to LSD1 inhibition.
Haematologica
; 105(8): 2105-2117, 2020 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-31537694
2.
Inhibition of the lysine demethylase LSD1 modulates the balance between inflammatory and antiviral responses against coronaviruses.
Sci Signal
; 16(816): eade0326, 2023 12 19.
Artículo
en Inglés
| MEDLINE | ID: mdl-38113337
3.
Measurement of S-methylcysteine and S-methyl-mercapturic acid in human urine by alkyl-chloroformate extractive derivatization and isotope-dilution gas chromatography-mass spectrometry.
Biomed Chromatogr
; 25(3): 330-43, 2011 Mar.
Artículo
en Inglés
| MEDLINE | ID: mdl-21110385
4.
Enhanced activity or resistance of adenosine derivatives towards adenosine deaminase-catalyzed deamination: Influence of ribose modifications.
Bioorg Med Chem Lett
; 19(10): 2877-9, 2009 May 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-19361992
5.
Novel potent inhibitors of the histone demethylase KDM1A (LSD1), orally active in a murine promyelocitic leukemia model.
Future Med Chem
; 9(11): 1161-1174, 2017 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-28722470
6.
Thieno[3,2-b]pyrrole-5-carboxamides as New Reversible Inhibitors of Histone Lysine Demethylase KDM1A/LSD1. Part 2: Structure-Based Drug Design and Structure-Activity Relationship.
J Med Chem
; 60(5): 1693-1715, 2017 03 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-28186757
7.
Thieno[3,2-b]pyrrole-5-carboxamides as New Reversible Inhibitors of Histone Lysine Demethylase KDM1A/LSD1. Part 1: High-Throughput Screening and Preliminary Exploration.
J Med Chem
; 60(5): 1673-1692, 2017 03 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-28186755
8.
Discovery of a Novel Inhibitor of Histone Lysine-Specific Demethylase 1A (KDM1A/LSD1) as Orally Active Antitumor Agent.
J Med Chem
; 59(4): 1501-17, 2016 Feb 25.
Artículo
en Inglés
| MEDLINE | ID: mdl-26702542
9.
Further insights into the SAR of α-substituted cyclopropylamine derivatives as inhibitors of histone demethylase KDM1A.
Eur J Med Chem
; 92: 377-86, 2015 Mar 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-25585008
10.
Synthesis, biological activity and mechanistic insights of 1-substituted cyclopropylamine derivatives: a novel class of irreversible inhibitors of histone demethylase KDM1A.
Eur J Med Chem
; 86: 352-63, 2014 Oct 30.
Artículo
en Inglés
| MEDLINE | ID: mdl-25173853
11.
Synthesis of enantiopure Delta2-isoxazoline derivatives and evaluation of their affinity and efficacy profiles at human beta-adrenergic receptor subtypes.
Bioorg Med Chem
; 14(13): 4393-401, 2006 Jul 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-16530417
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