Detalles de la búsqueda
1.
Author Correction: Chimeric peptidomimetic antibiotics against Gram-negative bacteria.
Nature
; 576(7786): E5, 2019 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-31758154
2.
Chimeric peptidomimetic antibiotics against Gram-negative bacteria.
Nature
; 576(7787): 452-458, 2019 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-31645764
3.
Use of CRISPR/Cas9 with Homology-Directed Repair to Gene-Edit Topoisomerase IIß in Human Leukemia K562 Cells: Generation of a Resistance Phenotype.
J Pharmacol Exp Ther
; 389(2): 186-196, 2024 Apr 18.
Artículo
en Inglés
| MEDLINE | ID: mdl-38508753
4.
UCHL1 as a novel target in breast cancer: emerging insights from cell and chemical biology.
Br J Cancer
; 126(1): 24-33, 2022 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-34497382
5.
Redox Activity of Flavonoids: Impact on Human Health, Therapeutics, and Chemical Safety.
Chem Res Toxicol
; 35(2): 140-162, 2022 02 21.
Artículo
en Inglés
| MEDLINE | ID: mdl-35045245
6.
Role of Citrus medica L. Fruits Extract in Combatting the Hematological and Hepatic Toxic Effects of Carbofuran.
Chem Res Toxicol
; 34(8): 1890-1902, 2021 08 16.
Artículo
en Inglés
| MEDLINE | ID: mdl-34264070
7.
Photochemical Probe Identification of a Small-Molecule Inhibitor Binding Site in Hedgehog Acyltransferase (HHAT)*.
Angew Chem Int Ed Engl
; 60(24): 13542-13547, 2021 06 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-33768725
8.
Discovery of a Potent and Selective Covalent Inhibitor and Activity-Based Probe for the Deubiquitylating Enzyme UCHL1, with Antifibrotic Activity.
J Am Chem Soc
; 142(28): 12020-12026, 2020 07 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-32579346
9.
Anti-diarrheal activities of phytol along with its possible mechanism of action through in-vivo and in-silico models.
Cell Mol Biol (Noisy-le-grand)
; 66(4): 243-249, 2020 Jun 25.
Artículo
en Inglés
| MEDLINE | ID: mdl-32583783
10.
Anticancer activity of thymol: A literature-based review and docking study with Emphasis on its anticancer mechanisms.
IUBMB Life
; 71(1): 9-19, 2019 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-30308112
11.
Hepatoprotective and Antioxidant Activities of Justicia gendarussa Leaf Extract in Carbofuran-Induced Hepatic Damage in Rats.
Chem Res Toxicol
; 32(12): 2499-2508, 2019 12 16.
Artículo
en Inglés
| MEDLINE | ID: mdl-31696704
12.
Protective Role of Syzygium Cymosum Leaf Extract Against Carbofuran-Induced Hematological and Hepatic Toxicities.
Chem Res Toxicol
; 32(8): 1619-1629, 2019 08 19.
Artículo
en Inglés
| MEDLINE | ID: mdl-31334637
13.
Fragment-Based Drug Design Facilitated by Protein-Templated Click Chemistry: Fragment Linking and Optimization of Inhibitors of the Aspartic Protease Endothiapepsin.
Chemistry
; 22(42): 14826-14830, 2016 Oct 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-27604032
14.
Furoates and thenoates inhibit pyruvate dehydrogenase kinase 2 allosterically by binding to its pyruvate regulatory site.
J Enzyme Inhib Med Chem
; 31(sup4): 170-175, 2016.
Artículo
en Inglés
| MEDLINE | ID: mdl-27435185
15.
Dynamic combinatorial chemistry: a tool to facilitate the identification of inhibitors for protein targets.
Chem Soc Rev
; 44(8): 2455-88, 2015 Apr 21.
Artículo
en Inglés
| MEDLINE | ID: mdl-25706945
16.
Fragment Linking and Optimization of Inhibitors of the Aspartic Protease Endothiapepsin: Fragment-Based Drug Design Facilitated by Dynamic Combinatorial Chemistry.
Angew Chem Int Ed Engl
; 55(32): 9422-6, 2016 08 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-27400756
17.
Correction to "Discovery of a Potent and Selective Covalent Inhibitor and Activity-Based Probe for the Deubiquitylating Enzyme UCHL1, with Antifibrotic Activity".
J Am Chem Soc
; 142(35): 15199, 2020 Sep 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-32812749
18.
Structure-Based Optimization of Inhibitors of the Aspartic Protease Endothiapepsin.
Int J Mol Sci
; 16(8): 19184-94, 2015 Aug 14.
Artículo
en Inglés
| MEDLINE | ID: mdl-26287174
19.
Structure-based design of inhibitors of the aspartic protease endothiapepsin by exploiting dynamic combinatorial chemistry.
Angew Chem Int Ed Engl
; 53(12): 3259-63, 2014 Mar 17.
Artículo
en Inglés
| MEDLINE | ID: mdl-24532096
20.
Discovery of potent and selective activity-based probes (ABPs) for the deubiquitinating enzyme USP30.
RSC Chem Biol
; 5(5): 439-446, 2024 May 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-38725909