Detalles de la búsqueda
1.
Dual targeting of acetylcholinesterase and tau aggregation: Design, synthesis and evaluation of multifunctional deoxyvasicinone analogues for Alzheimer's disease.
Bioorg Chem
; 116: 105354, 2021 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-34562674
2.
Leukotriene A4 Hydrolase Activation and Leukotriene B4 Production by Eosinophils in Severe Asthma.
Am J Respir Cell Mol Biol
; 60(4): 413-419, 2019 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-30352167
3.
Suppression of aspirin-mediated eosinophil activation by prostaglandin E2: Relevance to aspirin and nonsteroidal anti-inflammatory drug hypersensitivity.
Ann Allergy Asthma Immunol
; 123(5): 503-506, 2019 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-31513909
4.
Temperature Control after Cardiac Arrest. When to Start? How Long? How Cold?
Am J Respir Crit Care Med
; 198(10): 1331-1333, 2018 Nov 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-30199655
5.
Improved Pharmacokinetic and Pharmacodynamic Profile of Deuterium-Reinforced Tricyclic Antidepressants Doxepin, Dosulepin, and Clomipramine in Animal Models.
Eur J Drug Metab Pharmacokinet
; 49(2): 181-190, 2024 Mar.
Artículo
en Inglés
| MEDLINE | ID: mdl-38172422
6.
Discovery of Novel Diesters Incorporating Kojic Acid With NSAIDs and Palmitic Acid as Dual Inhibitor of Melanogenesis and Inflammation.
J Pharm Sci
; 113(7): 1769-1778, 2024 Jul.
Artículo
en Inglés
| MEDLINE | ID: mdl-38663499
7.
Correction: Therapeutic interventions on human breast cancer xenografts promote systemic dissemination of oncogenes.
PLoS One
; 19(3): e0301650, 2024.
Artículo
en Inglés
| MEDLINE | ID: mdl-38547094
8.
Therapeutic interventions on human breast cancer xenografts promote systemic dissemination of oncogenes.
PLoS One
; 19(2): e0298042, 2024.
Artículo
en Inglés
| MEDLINE | ID: mdl-38346047
9.
Cell-free chromatin particles released from dying cells inflict mitochondrial damage and ROS production in living cells.
Cell Death Discov
; 10(1): 30, 2024 Jan 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-38225229
10.
Reinvestigation of diphenylmethylpiperazine analogues of pyrazine as new class of Plasmodial cysteine protease inhibitors for the treatment of malaria.
RSC Med Chem
; 15(3): 1022-1037, 2024 Mar 20.
Artículo
en Inglés
| MEDLINE | ID: mdl-38516592
11.
Identification, in-vitro anti-plasmodial assessment and docking studies of series of tetrahydrobenzothieno[2,3-d]pyrimidine-acetamide molecular hybrids as potential antimalarial agents.
Eur J Med Chem
; 248: 115055, 2023 Feb 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-36621136
12.
Multicomponent Petasis reaction for the identification of pyrazine based multi-target directed anti-Alzheimer's agents: In-silico design, synthesis, and characterization.
Eur J Med Chem
; 254: 115354, 2023 Jun 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-37043996
13.
Cell-free chromatin particles released from dying cancer cells activate immune checkpoints in human lymphocytes: implications for cancer therapy.
Front Immunol
; 14: 1331491, 2023.
Artículo
en Inglés
| MEDLINE | ID: mdl-38274821
14.
Naphthyl bearing 1,3,4-thiadiazoleacetamides targeting the parasitic folate pathway as anti-infectious agents: in silico, synthesis, and biological approach.
RSC Med Chem
; 14(12): 2768-2781, 2023 Dec 13.
Artículo
en Inglés
| MEDLINE | ID: mdl-38107179
15.
A pro-oxidant combination of resveratrol and copper down-regulates multiple biological hallmarks of ageing and neurodegeneration in mice.
Sci Rep
; 12(1): 17209, 2022 10 14.
Artículo
en Inglés
| MEDLINE | ID: mdl-36241685
16.
A novel pro-oxidant combination of resveratrol and copper reduces transplant related toxicities in patients receiving high dose melphalan for multiple myeloma (RESCU 001).
PLoS One
; 17(2): e0262212, 2022.
Artículo
en Inglés
| MEDLINE | ID: mdl-35120140
17.
A pro-oxidant combination of resveratrol and copper down-regulates hallmarks of cancer and immune checkpoints in patients with advanced oral cancer: Results of an exploratory study (RESCU 004).
Front Oncol
; 12: 1000957, 2022.
Artículo
en Inglés
| MEDLINE | ID: mdl-36185249
18.
A New Perspective on the Origin of DNA Double-Strand Breaks and Its Implications for Ageing.
Genes (Basel)
; 12(2)2021 01 26.
Artículo
en Inglés
| MEDLINE | ID: mdl-33530310
19.
Design, synthesis, crystal structure and anti-plasmodial evaluation of tetrahydrobenzo[4,5]thieno[2,3-d]pyrimidine derivatives.
RSC Med Chem
; 12(6): 970-981, 2021 Jun 23.
Artículo
en Inglés
| MEDLINE | ID: mdl-34223162
20.
Discovery of new phenyl sulfonyl-pyrimidine carboxylate derivatives as the potential multi-target drugs with effective anti-Alzheimer's action: Design, synthesis, crystal structure and in-vitro biological evaluation.
Eur J Med Chem
; 215: 113224, 2021 Apr 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-33582578