Detalles de la búsqueda
1.
Dystrophin and mini-dystrophin quantification by mass spectrometry in skeletal muscle for gene therapy development in Duchenne muscular dystrophy.
Gene Ther
; 29(10-11): 608-615, 2022 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-34737451
2.
Structure-function relationships of the soluble form of the antiaging protein Klotho have therapeutic implications for managing kidney disease.
J Biol Chem
; 295(10): 3115-3133, 2020 03 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-32005658
3.
Highly specific and sensitive measurements of human and monkey interleukin 21 using sequential protein and tryptic peptide immunoaffinity LC-MS/MS.
Anal Chem
; 85(11): 5522-9, 2013 Jun 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-23638938
4.
Analysis of ß-nerve growth factor and its precursor during human pregnancy by immunoaffinity-liquid chromatography tandem mass spectrometry.
Sci Rep
; 13(1): 9180, 2023 06 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-37280257
5.
High-performance liquid chromatography-tandem mass spectrometry assay of fatty acid amide hydrolase (FAAH) in blood: FAAH inhibition as clinical biomarker.
Anal Biochem
; 421(2): 556-65, 2012 Feb 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-22107886
6.
Application of Immunoaffinity Mass Spectrometry (IA-MS) for Protein Biomarker Quantification.
Methods Mol Biol
; 2466: 111-119, 2022.
Artículo
en Inglés
| MEDLINE | ID: mdl-35585314
7.
2021 White Paper on Recent Issues in Bioanalysis: Mass Spec of Proteins, Extracellular Vesicles, CRISPR, Chiral Assays, Oligos; Nanomedicines Bioanalysis; ICH M10 Section 7.1; Non-Liquid & Rare Matrices; Regulatory Inputs (Part 1A - Recommendations on Endogenous Compounds, Small Molecules, Complex Methods, Regulated Mass Spec of Large Molecules, Small Molecule, PoC & Part 1B - Regulatory Agencies' Inputs on Bioanalysis, Biomarkers, Immunogenicity, Gene & Cell Therapy and Vaccine).
Bioanalysis
; 14(9): 505-580, 2022 May.
Artículo
en Inglés
| MEDLINE | ID: mdl-35578993
8.
A Mechanistic Site-Of-Action Model: A Tool for Informing Right Target, Right Compound, And Right Dose for Therapeutic Antagonistic Antibody Programs.
Front Bioinform
; 1: 731340, 2021.
Artículo
en Inglés
| MEDLINE | ID: mdl-36303796
9.
Enhancing the utility of alanine aminotransferase as a reference standard biomarker for drug-induced liver injury.
Regul Toxicol Pharmacol
; 56(3): 237-46, 2010 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-19903504
10.
LC-MS/MS mediated absolute quantification and comparison of bile salt export pump and breast cancer resistance protein in livers and hepatocytes across species.
Anal Chem
; 81(6): 2251-9, 2009 Mar 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-19209887
11.
2019 White Paper on Recent Issues in Bioanalysis: Chromatographic Assays (Part 1 - Innovation in Small Molecules and Oligonucleotides & Mass Spectrometric Method Development Strategies for Large Molecule Bioanalysis).
Bioanalysis
; 11(22): 2029-2048, 2019 Nov.
Artículo
en Inglés
| MEDLINE | ID: mdl-31808716
12.
Targeted disruption of murine organic anion-transporting polypeptide 1b2 (Oatp1b2/Slco1b2) significantly alters disposition of prototypical drug substrates pravastatin and rifampin.
Mol Pharmacol
; 74(2): 320-9, 2008 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-18413659
13.
2018 White Paper on Recent Issues in Bioanalysis: focus on immunogenicity assays by hybrid LBA/LCMS and regulatory feedback (Part 2 - PK, PD & ADA assays by hybrid LBA/LCMS & regulatory agencies' inputs on bioanalysis, biomarkers and immunogenicity).
Bioanalysis
; 10(23): 1897-1917, 2018 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-30488729
14.
Reduced serum myostatin concentrations associated with genetic muscle disease progression.
J Neurol
; 264(3): 541-553, 2017 Mar.
Artículo
en Inglés
| MEDLINE | ID: mdl-28074267
15.
2017 White Paper: rise of hybrid LBA/LCMS immunogenicity assays (Part 2: hybrid LBA/LCMS biotherapeutics, biomarkers & immunogenicity assays and regulatory agencies' inputs).
Bioanalysis
; 9(23): 1895-1912, 2017 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-29205053
16.
Quantitative measurements of GDF-8 using immunoaffinity LC-MS/MS.
Proteomics Clin Appl
; 10(5): 597-604, 2016 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-26846723
17.
Dystrophin-deficient dogs with reduced myostatin have unequal muscle growth and greater joint contractures.
Skelet Muscle
; 6: 14, 2016.
Artículo
en Inglés
| MEDLINE | ID: mdl-27047655
18.
IL1RL1 asthma risk variants regulate airway type 2 inflammation.
JCI Insight
; 1(14): e87871, 2016 09 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-27699235
19.
2016 White Paper on recent issues in bioanalysis: focus on biomarker assay validation (BAV): (Part 2 - Hybrid LBA/LCMS and input from regulatory agencies).
Bioanalysis
; 8(23): 2457-2474, 2016 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-27855509
20.
Tissue bioanalysis of biotherapeutics and drug targets to support PK/PD.
Bioanalysis
; 4(21): 2589-604, 2012 Nov.
Artículo
en Inglés
| MEDLINE | ID: mdl-23173794