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1.
Pharmacokinetics and exposure-efficacy relationships of omalizumab in patients with nasal polyps.
Pulm Pharmacol Ther
; 71: 102080, 2021 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-34592476
2.
A randomized, placebo-controlled trial evaluating effects of lebrikizumab on airway eosinophilic inflammation and remodelling in uncontrolled asthma (CLAVIER).
Clin Exp Allergy
; 50(12): 1342-1351, 2020 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-32909660
3.
Efficacy and safety of lebrikizumab (an anti-IL-13 monoclonal antibody) in adults with moderate-to-severe atopic dermatitis inadequately controlled by topical corticosteroids: A randomized, placebo-controlled phase II trial (TREBLE).
J Am Acad Dermatol
; 78(5): 863-871.e11, 2018 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-29353026
4.
Model-based clinical pharmacology profiling and exposure-response relationships of the efficacy and biomarker of lebrikizumab in patients with moderate-to-severe asthma.
Pulm Pharmacol Ther
; 46: 88-98, 2017 Oct.
Artículo
en Inglés
| MEDLINE | ID: mdl-28843617
5.
Lebrikizumab in moderate-to-severe asthma: pooled data from two randomised placebo-controlled studies.
Thorax
; 70(8): 748-56, 2015 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-26001563
6.
Dose-ranging study of lebrikizumab in asthmatic patients not receiving inhaled steroids.
J Allergy Clin Immunol
; 132(3): 567-574.e12, 2013 Sep.
Artículo
en Inglés
| MEDLINE | ID: mdl-23726041
7.
Factors contributing to the nonlinear pharmacokinetics of astegolimab: a close examination of potential causes.
Bioanalysis
; 15(21): 1305-1314, 2023 Nov.
Artículo
en Inglés
| MEDLINE | ID: mdl-37791725
8.
Population Pharmacokinetics of Heptanoate in Healthy Subjects and Patients With Long-Chain Fatty Acid Oxidation Disorders Treated With Triheptanoin.
Clin Pharmacol Drug Dev
; 11(11): 1264-1272, 2022 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-35908210
9.
Population Pharmacokinetics and Exposure-Response Relationships of Astegolimab in Patients With Severe Asthma.
J Clin Pharmacol
; 62(7): 905-917, 2022 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-34964491
10.
Efficacy, safety, and tolerability of lebrikizumab in adolescent patients with uncontrolled asthma (ACOUSTICS).
Clin Transl Allergy
; 12(7): e12176, 2022 Jul.
Artículo
en Inglés
| MEDLINE | ID: mdl-35846226
11.
Population repeated time-to-event analysis of exacerbations in asthma patients: A novel approach for predicting asthma exacerbations based on biomarkers, spirometry, and diaries/questionnaires.
CPT Pharmacometrics Syst Pharmacol
; 10(10): 1221-1235, 2021 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-34346168
12.
Translational and pharmacokinetic-pharmacodynamic application for the clinical development of GDC-0334, a novel TRPA1 inhibitor.
Clin Transl Sci
; 14(5): 1945-1954, 2021 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-34058071
13.
Comparability Considerations and Challenges for Expedited Development Programs for Biological Products.
Drugs R D
; 20(4): 301-306, 2020 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-32914381
14.
Efficacy and safety of lebrikizumab in adult patients with mild-to-moderate asthma not receiving inhaled corticosteroids.
Respir Med
; 134: 143-149, 2018 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-29413502
15.
A Pharmacokinetic Bioequivalence Study Comparing Pirfenidone Tablet and Capsule Dosage Forms in Healthy Adult Volunteers.
Adv Ther
; 34(9): 2071-2082, 2017 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-28808905
16.
Efficacy and safety of lebrikizumab in patients with uncontrolled asthma (LAVOLTA I and LAVOLTA II): replicate, phase 3, randomised, double-blind, placebo-controlled trials.
Lancet Respir Med
; 4(10): 781-796, 2016 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-27616196
17.
Effect of the MDR1 C3435T variant and P-glycoprotein induction on dicloxacillin pharmacokinetics.
J Clin Pharmacol
; 45(4): 411-21, 2005 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-15778422
18.
Quantitative structure-pharmacokinetic parameters relationships (QSPKR) analysis of antimicrobial agents in humans using simulated annealing k-nearest-neighbor and partial least-square analysis methods.
J Pharm Sci
; 93(10): 2535-44, 2004 Oct.
Artículo
en Inglés
| MEDLINE | ID: mdl-15349962
19.
Functional characterization of monocarboxylic acid, large neutral amino acid, bile acid and peptide transporters, and P-glycoprotein in MDCK and Caco-2 cells.
J Pharm Sci
; 91(12): 2622-35, 2002 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-12434407
20.
Targeting membrane-expressed IgE B cell receptor with an antibody to the M1 prime epitope reduces IgE production.
Sci Transl Med
; 6(243): 243ra85, 2014 Jul 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-24990880