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1.
Activation of innate-adaptive immune machinery by poly(I:C) exposes a therapeutic vulnerability to prevent relapse in stroma-rich colon cancer.
Gut
; 71(12): 2502-2517, 2022 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-35477539
2.
Experiences of running a stratified medicine adaptive platform trial: Challenges and lessons learned from 10 years of the FOCUS4 trial in metastatic colorectal cancer.
Clin Trials
; 19(2): 146-157, 2022 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-35083924
3.
Image-based consensus molecular subtype (imCMS) classification of colorectal cancer using deep learning.
Gut
; 70(3): 544-554, 2021 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-32690604
4.
Molecular subtype-specific efficacy of anti-EGFR therapy in colorectal cancer is dependent on the chemotherapy backbone.
Br J Cancer
; 125(8): 1080-1088, 2021 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-34253874
5.
Clinical-Grade Detection of Microsatellite Instability in Colorectal Tumors by Deep Learning.
Gastroenterology
; 159(4): 1406-1416.e11, 2020 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-32562722
6.
Immune status is prognostic for poor survival in colorectal cancer patients and is associated with tumour hypoxia.
Br J Cancer
; 123(8): 1280-1288, 2020 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-32684627
7.
Standardising RNA profiling based biomarker application in cancer-The need for robust control of technical variables.
Biochim Biophys Acta Rev Cancer
; 1868(1): 258-272, 2017 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-28549623
8.
Confirmation that somatic mutations of beta-2 microglobulin correlate with a lack of recurrence in a subset of stage II mismatch repair deficient colorectal cancers from the QUASAR trial.
Histopathology
; 75(2): 236-246, 2019 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-31062389
9.
Prospective patient stratification into robust cancer-cell intrinsic subtypes from colorectal cancer biopsies.
J Pathol
; 245(1): 19-28, 2018 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-29412457
10.
HER2 overexpression and amplification as a potential therapeutic target in colorectal cancer: analysis of 3256 patients enrolled in the QUASAR, FOCUS and PICCOLO colorectal cancer trials.
J Pathol
; 238(4): 562-70, 2016 Mar.
Artículo
en Inglés
| MEDLINE | ID: mdl-26690310
11.
Panitumumab and irinotecan versus irinotecan alone for patients with KRAS wild-type, fluorouracil-resistant advanced colorectal cancer (PICCOLO): a prospectively stratified randomised trial.
Lancet Oncol
; 14(8): 749-59, 2013 Jul.
Artículo
en Inglés
| MEDLINE | ID: mdl-23725851
12.
Image-based consensus molecular subtyping in rectal cancer biopsies and response to neoadjuvant chemoradiotherapy.
NPJ Precis Oncol
; 8(1): 89, 2024 Apr 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-38594327
13.
Pathway level subtyping identifies a slow-cycling biological phenotype associated with poor clinical outcomes in colorectal cancer.
Nat Genet
; 56(3): 458-472, 2024 Mar.
Artículo
en Inglés
| MEDLINE | ID: mdl-38351382
14.
FOCUS4 biomarker laboratories: from the benefits to the practical and logistical issues faced during 6 years of centralised testing.
J Clin Pathol
; 76(8): 548-554, 2023 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-35256486
15.
Generalizable biomarker prediction from cancer pathology slides with self-supervised deep learning: A retrospective multi-centric study.
Cell Rep Med
; 4(4): 100980, 2023 04 18.
Artículo
en Inglés
| MEDLINE | ID: mdl-36958327
16.
Associations between AI-Assisted Tumor Amphiregulin and Epiregulin IHC and Outcomes from Anti-EGFR Therapy in the Routine Management of Metastatic Colorectal Cancer.
Clin Cancer Res
; 29(20): 4153-4165, 2023 10 13.
Artículo
en Inglés
| MEDLINE | ID: mdl-37363997
17.
Transformer-based biomarker prediction from colorectal cancer histology: A large-scale multicentric study.
Cancer Cell
; 41(9): 1650-1661.e4, 2023 09 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-37652006
18.
Spend less to achieve more: Economic analysis of intermittent versus continuous cetuximab in KRAS wild-type patients with metastatic colorectal cancer.
J Cancer Policy
; 33: 100342, 2022 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-35718327
19.
Ultra-Low DNA Input into Whole Genome Methylation Assays and Detection of Oncogenic Methylation and Copy Number Variants in Circulating Tumour DNA.
Epigenomes
; 5(1): 6, 2021 02 19.
Artículo
en Inglés
| MEDLINE | ID: mdl-33777442
20.
Adaptor Template Oligo-Mediated Sequencing (ATOM-Seq) is a new ultra-sensitive UMI-based NGS library preparation technology for use with cfDNA and cfRNA.
Sci Rep
; 11(1): 3138, 2021 02 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-33542447