Detalles de la búsqueda
1.
Preclinical efficacy of potent and selective menin-KMT2A inhibitor JNJ-75276617 in KMT2A- and NPM1-altered leukemias.
Blood
; 2024 Jun 21.
Artículo
en Inglés
| MEDLINE | ID: mdl-38905635
2.
Considerations for the Identification and Conveyance of Clinical Pathology Findings in Preclinical Toxicity Studies: Results From the 9th ESTP International Expert Workshop.
Toxicol Pathol
; : 1926233241245108, 2024 Apr 25.
Artículo
en Inglés
| MEDLINE | ID: mdl-38661116
3.
Evaluation of Novel Urinary Biomarkers in Beagle Dogs With Amphotericin B-Induced Kidney Injury.
Int J Toxicol
; 42(2): 146-155, 2023.
Artículo
en Inglés
| MEDLINE | ID: mdl-36427267
4.
Drug-specific T-cell responses in patients with liver injury following treatment with the BACE inhibitor atabecestat.
Allergy
; 76(6): 1825-1835, 2021 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-33150583
5.
Bilateral Symmetrical Idiopathic Necrotizing Encephalopathy: A New Syndrome in Sprague-Dawley Rats.
Toxicol Pathol
; 43(8): 1141-8, 2015 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-26511844
6.
Evaluation of miR-122 and other biomarkers in distinct acute liver injury in rats.
Toxicol Pathol
; 41(5): 795-804, 2013 Jul.
Artículo
en Inglés
| MEDLINE | ID: mdl-23143187
7.
The inhibin B response to the testicular toxicant 1, 3 dinitrobenzene in male rats.
Birth Defects Res B Dev Reprod Toxicol
; 98(1): 29-34, 2013 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-23348823
8.
Analytic evaluation of a human ELISA kit for measurement of inhibin B in rat samples.
Birth Defects Res B Dev Reprod Toxicol
; 98(1): 4-16, 2013 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-23349040
9.
Intravenous Administration of Ad26.COV2.S Does Not Induce Thrombocytopenia or Thrombotic Events or Affect SARS-CoV-2 Spike Protein Bioavailability in Blood Compared with Intramuscular Vaccination in Rabbits.
Vaccines (Basel)
; 11(12)2023 Nov 30.
Artículo
en Inglés
| MEDLINE | ID: mdl-38140195
10.
Discovery of an Oral, Beyond-Rule-of-Five Mcl-1 Protein-Protein Interaction Modulator with the Potential of Treating Hematological Malignancies.
J Med Chem
; 66(9): 6122-6148, 2023 05 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-37114951
11.
Efferent duct toxicity with secondary testicular changes in rats following administration of a novel leukotriene A4 hydrolase inhibitor.
Toxicol Pathol
; 40(5): 705-14, 2012 Jul.
Artículo
en Inglés
| MEDLINE | ID: mdl-22552396
12.
Tissue Kim-1 and urinary clusterin as early indicators of cisplatin-induced acute kidney injury in rats.
Toxicol Pathol
; 40(7): 1049-62, 2012 Oct.
Artículo
en Inglés
| MEDLINE | ID: mdl-22581811
13.
Discovery and Pharmacological Characterization of JNJ-64619178, a Novel Small-Molecule Inhibitor of PRMT5 with Potent Antitumor Activity.
Mol Cancer Ther
; 20(12): 2317-2328, 2021 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-34583982
14.
Hemorrhagic cardiomyopathy in male mice treated with an NNRTI: the role of vitamin K.
Toxicol Pathol
; 36(2): 321-9, 2008 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-18367644
15.
Analytical performance of a commercial multiplex Luminex-based cytokine panel in the rat.
J Pharmacol Toxicol Methods
; 91: 43-49, 2018.
Artículo
en Inglés
| MEDLINE | ID: mdl-29371052
16.
Renal tubular and adrenal medullary tumors in the 2-year rat study with canagliflozin confirmed to be secondary to carbohydrate (glucose) malabsorption in the 15-month mechanistic rat study.
Chem Biol Interact
; 277: 85-90, 2017 Nov 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-28916336
17.
Chronic drug-induced effects on contractile motion properties and cardiac biomarkers in human induced pluripotent stem cell-derived cardiomyocytes.
Br J Pharmacol
; 174(21): 3766-3779, 2017 Nov.
Artículo
en Inglés
| MEDLINE | ID: mdl-28094846
18.
Evaluation of the diagnostic potential of urinary N-Acetyltyramine-O,ß-glucuronide (NATOG) as diagnostic biomarker for Onchocerca volvulus infection.
Parasit Vectors
; 9(1): 302, 2016 05 23.
Artículo
en Inglés
| MEDLINE | ID: mdl-27216752
19.
Cross-laboratory analytical validation of the cardiac biomarker NT-proANP in rat.
J Pharmacol Toxicol Methods
; 77: 58-65, 2016.
Artículo
en Inglés
| MEDLINE | ID: mdl-26516096
20.
Effects of pre-treatment with amantadine on morphine induced antinociception during second phase formalin responses in rats.
Pain
; 119(1-3): 159-167, 2005 Dec 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-16297559