ABSTRACT
Utilizando-se soros imune e de animais tratados com Trypanosominum TC D30, em presenca de complemento, observa-se que ocorre a lise de tripomastigotas sanguineos da cepa Y. Quando os referidos soros sao adicionados de soro humano normal inativado, os tripomastigotas sanguineos nao sao lisados. A lise de tripomastigotas mediada por complemento, revela a presenca de anticor-pos liticos no soro imune e no soro de camundongos tratados com o TrypanosominumTC D30, sugerindo a resistencia do hospedeiro contra o T. cruzi
Subject(s)
Rats , Animals , Biotherapics/therapeutic use , Chagas Disease/prevention & control , Trypanosoma cruzi , Antibody Formation , Immunity, ActiveABSTRACT
The trypomastigotes were aglutinated by imune animals serum in several dilutions. However, when treated with biotherapic D30, the trypomastigotes were not aglutinate by all dilutions utilized. When diluted 1:2 rat serum aglutination ocorred. The results suggest: the presence of aglutinating antibodies appear soon and is related with the control of the acute phase of humoral immunity