ABSTRACT
In this era of genomics and other exciting technical advances, research on the biology of aging is undergoing a renaissance. This report summarizes 10 cutting-edge areas of research covered in symposia that spanned such topics as stem cells, novel vaccine strategies, nutritional sensing, new concepts of Parkinson's disease, high throughput screening for aging interventions, manipulating telomerase in cancer and immunodeficiency, synergy between aging and HIV disease, and epigenetic influences on aging. Novel animal models, including those showing no evidence of aging, as well as ethical and political implications of embryonic stem cells and alternative medicine are also discussed.
Subject(s)
Biological Science Disciplines , Geriatrics , Research , Aging , Animals , Epigenesis, Genetic , HIV Infections , Homeopathy , Humans , Mass Screening , Parkinson Disease , Societies, Medical , Stem Cells , Stochastic Processes , Telomerase , Telomere , VaccinationABSTRACT
In a geriatric hospital in France, only 80 (21%) of 390 healthcare workers (HCWs) were vaccinated against influenza. Predictive factors for accepting influenza vaccination were occupation as a physician (odds ratio [OR], 9.79), previous receipt of influenza vaccination (OR, 36), and desire to protect their own health (OR, 2.42) and residents' health (OR, 3.68). Predictive factors for refusing influenza vaccination were occupation as a nurse (OR, 6.41) or nursing assistant (OR, 4.04) and belief that homeopathic medication is more effective than the vaccine (OR, 5.75).
Subject(s)
Geriatrics , Health Knowledge, Attitudes, Practice , Hospitals, University , Influenza Vaccines/administration & dosage , Medical Staff, Hospital/psychology , Nursing Staff, Hospital/psychology , Adult , Attitude of Health Personnel , Female , France , Health Care Surveys , Humans , Influenza, Human/prevention & control , Male , Patient Acceptance of Health Care , Treatment Refusal , Vaccination/psychology , WorkforceABSTRACT
The fact that, due to demographic changes, gerontology and geriatrics are gaining ever more importance gives rise to more questions regarding the history of the science of aging. Based on unpublished sources and relevant publications by Max Bürger, the doyen of gerontological research in Germany, our contributions trace the beginnings of age research in Germany. Our results confirm Bürger as the dominant expert in this field in the first decades of its emergence. Bürger was primarily interested in basic medical-scientific research, and less in clinical geriatrics. His scientific goal was not to establish a medicine for the elderly but a theory of life changes ("biomorphosis"). From the start, he saw aging as a physiological process--a view that is still valid today. His concept of "biomorphosis", however, did not catch on and reveals a constriction in Bürger's thinking, which was to some extent influenced by Hans Driesch's vitalism. Interdisciplinary approaches are noticeable in the natural sciences rather than the humanities or social sciences. Bürger's research was also influenced by the political system he lived in. During National Socialism, which Bürger joined--at least formally--in 1937, his research into labour economics and aging met with considerable interest in connection with the general mobilisation of resources. East Germany also had an interest in questions of labour productivity in old age and the extension of the working life, which meant that Bürger remained a sought-after physician and scientist up into the 1960s. As he grew older himself, Bürger's initially deficit-oriented view of old age gave way to a more positive presentation that attached greater weight to the resources of old age.
Subject(s)
Geriatrics/history , Research/history , Germany , History, 19th Century , History, 20th CenturyABSTRACT
BACKGROUND: Adverse drug reactions (ADRs) present a challenging and expensive public health problem. Polypharmacy is defined according to the WHO criteria as the, "concurrent use of five or more different prescription medication". Elderly are more prone to adverse reactions due to comorbid conditions, longer lists of medications and sensitivity to drug effects. The aim of the study is to estimate the incidence and strength of association of ADRs due to polypharmacy among the geriatric cohort attending outpatient clinics at a tertiary care center. METHODS: A hospital based prospective cohort study was conducted at ambulatory care clinics of Aga Khan University Hospital April 2012 to March 2013. One thousand geriatrics patients (age ≥ 65 years) visiting ambulatory clinics were identified. They were divided on the basis of exposure (polypharmacy vs. no polypharmacy). We followed them from the time of their enrollment (day zero) to six weeks, checking up on them once a week. Incidence was calculated and Cox Proportional Hazard Model estimates were used. RESULTS: The final analysis was performed on 1000 elderly patients. The occurrence of polypharmacy was 70% and the incidence of ADRs was 10.5% among the study cohort. The majority (30%) of patients were unable to read or write. The use of herbal medicine was reported by 3.2% of the patients and homeopathic by 3%. Our Cox adjusted model shows that polypharmacy was 2.3 times more associated with ADRs, con-current complementary and alternative medicine (CAM) was 7.4 times and those who cannot read and write were 1.5 times more associated with ADRs. CONCLUSION: The incidence of ADRs due to poly pharmacy is alarmingly high. The factors associated with ADRs are modifiable. Policies are needed to design and strengthen the prescription pattern.
Subject(s)
Drug-Related Side Effects and Adverse Reactions/epidemiology , Drug-Related Side Effects and Adverse Reactions/prevention & control , Geriatrics , Outpatients , Polypharmacy , Tertiary Care Centers , Aged , Aged, 80 and over , Cohort Studies , Female , Humans , Incidence , Male , Pakistan , Prospective Studies , Risk FactorsABSTRACT
Se realizó una revisión bibliográfica sobre depresión en el adulto mayor, ya que constituye la afección mental más frecuente en la tercera edad detectada por la consulta del equipo multidisciplinario de atención gerontológica del Policlínico Universitario Norte de Morón durante las consultas realizadas a los adultos mayores, de enero de 2008 a septiembre de 2009. Se pretende con ello elevar el nivel de conocimientos de los médicos sobre la depresión a través de la profundización del tema, haciendo especial énfasis en evitar la polifarmacia o indicación inadecuada de psicofármacos por las serias complicaciones que pueden producirse. Desde la antigüedad se utilizaban varias alternativas de tratamientos para la depresión como: plantas medicinales, el baile, la música; además, existen la terapia floral de Bach, la homeopatía y la terapia ocupacional. Se llega a la conclusión de que la terapia más efectiva es una adecuada relación y socialización del adulto mayor.
A literature review was carried out on depression in the elderly because it is the most common mental illness in the third age, detected by the multidisciplinary team of gerontology attention from North Morón University Polyclinic during consultations to seniors,from January 2008 to September 2009. It is intended to raise the level of knowledge of doctors about depression through the study of the topic, with particular emphasis on avoiding polypharmacy or inappropriate indication of psychotropic drugs by the serious complications that may occur.From ancient times were used several alternative treatments for depression such as: medicinal plants, dance, music, also there are Bach flower therapy, homeopathy and occupational therapy. It is concluded that the most effective therapy is an appropriate relationship and elderly socialization.
Subject(s)
Humans , Male , Female , Aged , Attitude of Health Personnel , Depression , Health Knowledge, Attitudes, Practice , Health of the Elderly , Geriatrics , Health Services for the AgedABSTRACT
Zinc gluconate glycine lozenges are an over-the-counter homeopathic remedy that significantly reduced the duration and severity of common colds in adults in 2 independent clinical trials. To evaluate the safety of zinc gluconate glycine lozenges in elderly individuals with 1 or more health conditions, with or without a cold. This randomized, double-blind, placebo-controlled, parallel-group trial enrolled men and women between 60 and 91 years of age, who self-administered 1 zinc gluconate glycine or placebo lozenge every 3 to 4 hours for 6 days. One or more of the following conditions was present in the study population: arthritis, cancer, depression, heart disease, hypertension, lung disease, osteoporosis, prostate disease, and stroke. Assessments were performed at baseline and at 7 (+/-1 day) and 14 days. The safety evaluation considered physical examinations, clinical laboratory tests, vital signs, adverse events, and concomitant medications. Of 75 persons enrolled, 66 completed the study. Safety assessments demonstrated no clinically significant differences between treatment groups. Four participants taking zinc tablets and 3 participants taking placebo tablets reported mild adverse events. Of those participants taking zinc tablets, 6 adverse events were possibly related to the study product and 2 adverse events were probably related to the study product. Of those participants taking placebo tablets, 3 adverse events were reported that were possibly related to the study product. No serious or clinically significant adverse events were noted. Zinc gluconate glycine lozenges are safe and well tolerated by a geriatric population and are suitable for prophylactic or therapeutic use to reduce the duration or severity of the common cold.
Subject(s)
Common Cold/drug therapy , Gluconates/therapeutic use , Glycine/therapeutic use , Zinc/therapeutic use , Aged , Aged, 80 and over , Common Cold/complications , Double-Blind Method , Female , Geriatrics , Gluconates/adverse effects , Glycine/adverse effects , Humans , Male , Middle Aged , Zinc/adverse effectsABSTRACT
El proceso de utilización de medicamentos es complejo y las personas adultas mayores tienden a tener un mayor número de entidades patológicas y de medicamentos que complica el uso racional, adecuado y seguro de los medicamentos. Se caracterizó la utilización de medicamentos y se identificaron algunos factores asociados que le determinan en la persona adulta mayor mediante las bases de datos del estudio Costa Rica Estudio de Longevidad y Envejecimiento Saludable, CRELES, en su primera ronda. Un 79 por ciento de la población consume medicamentos, en especial, 87 por ciento, de la Caja Costarricense de Seguro Social, CCSS; la mayoría fueron mujeres, 58 por ciento, residentes de la Gran Area Metropolitana. Los principales grupos terapéuticos fueron antihipertensivos, 18 por ciento, antitrombolíticos, 11 por ciento, diuréticos, 8 por ciento, hipoglicemiantes, 7 por ciento, hipolipemiantes, 6 por ciento en concordancia con el autoreporte de enfermedad; un 40 por ciento de las personas utilizan entre 1-3 medicamentos y el resto entre 4-17, polifarmacia. El mayor porcentaje de todas las agrupaciones de medicamentos, procedentes de servicios públicos/privados se encuentra en el grupo de edad predominante, 70-79 años; el abandono de los mismos se debió a preferencias de no uso de medicamentos, 54 por ciento, efectos secundarios, 29 por ciento, no disponibilidad, 8 por ciento, y precio elevado, 7 por ciento. A mayor edad hay más probabilidad de atención médica domiciliar, uso de medicamentos alopáticos-remedios naturales u homeopáticos; los cuales se ven favorecidos si la persona es mujer, 1.7 veces, con hipertensión, 4.9 veces; padece diabetes, 2.3 veces, o si tiene alguna enfermedad del corazón sin previo infarto, 1.3 veces. Estos elementos pueden ayudar a establecer estrategias en aspectos que atañen a la atención de la salud de la persona adulta mayor.
The use of medication is a complex process and the elderly tend to have a greater number of diseases and medicines, which complicates their rational, adequate and safe use. By means of the Costa Rican Study (first round) on Longevity and Health Aging (CRELES) data base, medication use was characterized in this population and some associate determining factors were identified. 79% of the elderly population consumes medications, mainly (87%) from the Caja Costarricense de Seguro Social. Most (58%) were women, residing in the Greater Metropolitan Area. According to self-reports of illness, the main therapeutic drugs were anti-hypertensives (18%), anti-thrombolytics (11%), diuretics (8%), anti-diabetics (7%), and cholesterol-lowering drugs (6%). 40% of the people use a range of 1-3 medications and the rest use a range of 4-17 medications.(AU)The largest percentage of all medication use groups, coming from the public/private services, is in the 70-79 age range. Discontinue of medication was due to personal preferences (54%), adverse effects (29%), unavailability of medication (8%), and high price (7%). As age increses there is a higher probability of domestic medical attention, higher use of allopathic medicine and natural or homeopathic remedies, which is favored is the person is female (1,7 times), has hypertension (4,9 times), suffers diabetes (2,3 times), or has a heart condition without previous infarction (1,3 times). These elements can help establish strategies in aspects that relate to health service provision in the elderly.
Subject(s)
Humans , Male , Female , Middle Aged , Drug Utilization , Geriatrics , Self Medication , Costa RicaSubject(s)
Drug Therapy , Geriatrics , Adrenal Cortex Hormones/administration & dosage , Aged , Aging , Analgesics/administration & dosage , Anti-Bacterial Agents/administration & dosage , Anticoagulants/administration & dosage , Antihypertensive Agents/administration & dosage , Cathartics/administration & dosage , Digitalis Glycosides/administration & dosage , Diuretics/administration & dosage , Drug Combinations , Drug Therapy, Combination , Humans , Hypnotics and Sedatives/administration & dosage , Hypoglycemic Agents/administration & dosage , Opium/administration & dosage , Psychotropic Drugs/administration & dosage , Thyroid Hormones/administration & dosageABSTRACT
More and more people are living well past the age of retirement. Average living conditions and improvements in the treatment of infectious and other acute diseases are gererally held to be the main reasons. This is resulting in an increasing percentage of the whole population being " elderly". However, many "elderly" people are really pretty healthy and lead very active lives.
Subject(s)
Humans , Aged , Homeopathy , Geriatrics/trends , Homeopathic TherapeuticsABSTRACT
Los extremos de la vida están influenciados por el desgaste normal que pone en vía de envejecimento al cuerpo; dan lugar a una especialidad que se llama geriatría.
Subject(s)
Geriatrics , Sclerosis/prevention & control , Symptomatology , Homeopathic RemedyABSTRACT
Los extremos de la vida están influenciados por el desgaste normal que pone en vía de envejecimento al cuerpo; dan lugar a una especialidad que se llama geriatría.
Subject(s)
Sclerosis/prevention & control , Geriatrics , Homeopathic Remedy , Signs and SymptomsABSTRACT
La geriatrie offre undomaine medical en pleine expansion ou les difficultes sont multiples. L'augnebtation de la longevite humaine favorise l'apparition de differents problemes pathologiques qu'il convient de resoudre pour assurer... (AU)
Subject(s)
Geriatrics , Homeopathy , Psoric Miasm , Sulphur , PsorinumABSTRACT
L'objectif principal de la geriatrie n'est pas seulement de prolonger la vie mais aussi d'en ameliorer la qualite afin que la periode de dependence ou de decheance physique et mentale qui caracterise trop souvent la fin de la vie... (AU)
Subject(s)
Geriatrics , Homeopathy , Aging/physiologyABSTRACT
Objetivos: Para identificar la presencia de problemas geriátricos en pacientes hospitalizados, realizamos una valoración geriátrica integral en 130 pacientes.- Comparar dos modelos de evaluación.- Proponer un addendum a la historia clínica. Material y métodos: Se diseña un estudio prospectivo-descriptivo de tipo transversal entre septiembre 1998 a enero 1999 en el Hospital Cayetano Heredia. En la segunda parte del estudio, se diseña un modelo comparativo de valoración geriátrica, calculando un tamaño muestras de 30 pacientes. Resultados: el promedio de edad fue de 73 mas y menos 8.8 años. Encontramos un promedio de 7 problemas geriátricos por cada paciente. deprivación sensorial ocurrió en 90 por ciento, incontinencia en 60 por ciento, depresión en 22 por ciento, caídas en 52 por ciento y confusión aguda en 28 por ciento de pacientes. Se identificó disfunción cognitiva en 20 por ciento de pacientes. En valoración funcional, encontramos 77 por ciento de dependencia, 91 por ciento tuvo riesgo y problema social. Se identificó mayor número de problemas en pacientes mayores de 75 y 85 años (p menor 0.05) y estuvo también asociado a mayor mortalidad (p menor 0.05). Conclusiones: La historia clínica convencional no es adecuada para identificar problemas geriátricos y para evaluar el estado funcional y social de adultos mayores. Validamos un addendum a la historia clínica con una sensibilidad de 60 - 100 por ciento y especificidad de 50 - 90 por ciento para una valoración geriátrica integral.
Subject(s)
Humans , Aged , Aging , Geriatrics , Homeopathic Anamnesis , Medical Records, Problem-Oriented , Cross-Sectional Studies , Prospective Studies , Hospitals, General , Epidemiology, DescriptiveABSTRACT
Plutot que de parler de remedes "inusites", je presenterai deux cas cliniques resolus par des remedes generalement "peu" utilises en geriatrie. En homeopathie les remedes n'ont pas d'age pas plus... (AU)
Subject(s)
Case Reports , Humans , Male , Female , Middle Aged , Aged , Geriatrics , Ferrum/therapeutic use , Sabadilla officinalis/therapeutic useABSTRACT
Il ne sera question ici que d'aspects pratiques: nous avons donc volontairement selectionne trois domaines de la neurologie ou le sujet age se retrouve le principal acteur pour en rappeler les principaux bouleversements qu'ils ont pu subir lors de ce dernier quart de siecle. (AU)
Subject(s)
Geriatrics , Homeopathy , Cerebrovascular Disorders/prevention & control , Alzheimer Disease/therapy , Parkinson Disease/therapyABSTRACT
El propósito del presente trabajo es comprobar si la práctica de yoga, especialmente adaptada para Adultos Mayores aplicada a ellos como método educativo no formal y herramienta de la gerontología, produce una mejora en su Satisfacción de Vida. Se tomó una muestra compuesta por 33 sujetos mayores de 50 años participantes sistemáticos de los cursos de gimnasia yoga en el periodo comprendido entre abril de 2002 y junio de 2004, quedando así una muestra heterogénea constituida por personas de ambos sexos, de distintas profesiones y prácticas sociales de la ciudad de Córdoba. La estrategia metodológica aplicada es de investigación descriptiva, adoptando un diseño de tipo observacional de series repetidas. Se aplicaron como instrumento de recolección de datos la escala LSIA - Life Satisfacción Index A -, creada por Neugarten, Havighurst y Tobin en la Universidad de Chicago, en EE. UU., en 1961, y modificada por Adams en 1969; una encuesta estructurada de trece preguntas cerradas y una ficha autoadministrada de siete preguntas cerradas y una abierta. Los resultados obtenidos de la cuantificación de la escala, ponen en evidencia un mejoramiento en el nivel de Satisfacción de Vida total y tres de sus subescalas (Deleite o gusto por la vida SD, Estado de ánimo SA y Congruencia entre objetivos y logros SC), tanto en general como en relación con las diferentes características de los sujetos.
Subject(s)
Humans , Male , Adult , Female , Aged , Adult Health , Aged , Aged/physiology , Muscle Stretching Exercises/methods , Methods , Quality of Life , Homeopathic Therapeutic Approaches , Yoga , Argentina , Geriatrics , Geriatrics/methods , Yoga/psychologyABSTRACT
El envejecimiento es un proceso dinámico, progresivo e irreversible en el que intervienen múltiples factores biológicos, psíquicos y sociales, que están interrelacionados. El olvido constante de la salud oral y una inexplicable separación de la boca del resto del cuerpo hecha por médicos y odontólogos, así como la creencia errada de algunos médicos que piensan que el odontólogo sólo tiene la obligación del cuidado y tratamiento de los dientes demuestra la falta de comunicación entre equipos de salud, siendo ésta imprescindible para la excelencia en los modelos de atención integral del paciente en cualquier etapa de su vida. El conocimiento de los cambios morfofisiológicos orofaciales relacionados con la edad permitirá diferenciar las características del proceso de envejecimiento, de los signos y síntomas de enfermedades; de manera que el odontólogo pueda establecer un diagnóstico y un plan de tratamiento acorde a las necesidades de los adultos mayores. Ya que la mayoría de las patologías bucales que afectan a la tercera edad son prevenibles sería beneficioso dar a conocer los cambios que se producen en el proceso de envejecimiento y las patologías que comúnmente se presentan a esta edad, para así motivar a los pacientes con el fin de adoptar medidas preventivas necesarias para el logro de una salud bucal general del individuo. Es importante que el odontólogo encargado de los pacientes geriátricos sea un profesional con ciertas cualidades y pertenecer a un grupo multidisciplinario de profesionales ligados a la tercera edad que además de la competencia técnica, debería tener la capacidad de comunicación, por el ser humano.
Subject(s)
Humans , Aging/pathology , Geriatrics , Dentistry , Preventive Dentistry , Signs and Symptoms , Signs in Homeopathy , Oral HealthABSTRACT
Este pequeno tratado estuda os medicamentos de acordo com sua prevalência em determinados quadros clínicos, valendo-se de dados experimentais, clínicos, toxicológicos e laboratoriais. Nosso objetivo é colaborar com o homeopata na definição do medicamento não antipsórico (o remédio comum de hahnemann) mais bem indicado para o primeiro tempo de tratamento.
Subject(s)
Homeopathic Therapeutics , Communicable Diseases , Gynecology , Acne Vulgaris , Pre-Eclampsia , GeriatricsABSTRACT
Este pequeno tratado estuda os medicamentos de acordo com sua prevalência em determinados quadros clínicos, valendo-se de dados experimentais, clínicos, toxicológicos e laboratoriais. Nosso objetivo é colaborar com o homeopata na definição do medicamento não antipsórico (o remédio comum de hahnemann) mais bem indicado para o primeiro tempo de tratamento...