Your browser doesn't support javascript.
loading
Show: 20 | 50 | 100
Results 1 - 1 de 1
Filter
Add more filters

Database
Language
Publication year range
1.
J Altern Complement Med ; 16(10): 1129-32, 2010 Oct.
Article in English | MEDLINE | ID: mdl-20954964

ABSTRACT

BACKGROUND: Molecular events that cause tumor formation upregulate a number of HOX genes, called switch genes, coding for RNA polymerase II transcription factors. Thus, in tumor cells, RNA polymerase II is more active than in other somatic cells. Amanita phalloides contains amanitin, inhibiting RNA polymerase II. Partial inhibition with amanitin influences tumor cell--but not normal cell--activity. OBJECTIVES: To widen the treatment spectrum, homeopathic dilutions of Amanita phalloides, containing amanitin, were given to a patient with leukemia. Monitoring the leukemic cell count, different doses of amanitin were given. RESULTS: The former duplication time of leukemic cells was 21 months. Within a period of 21 months, the cell count is stabilized to around 10(5)/µL. No leukemia-associated symptoms, liver damage, or continuous erythrocyte deprivation occur. CONCLUSIONS: This new principle of tumor therapy shows high potential to provide a gentle medical treatment.


Subject(s)
Amanita/chemistry , Amanitins/therapeutic use , Enzyme Inhibitors/therapeutic use , Homeopathy , Leukemia, Lymphocytic, Chronic, B-Cell/drug therapy , RNA Polymerase II/antagonists & inhibitors , Amanitins/pharmacology , Cell Count , Enzyme Inhibitors/pharmacology , Humans , Leukemia, Lymphocytic, Chronic, B-Cell/enzymology , Male , Middle Aged
SELECTION OF CITATIONS
SEARCH DETAIL