ABSTRACT
Introduction: Psoriasis which affects the skin of palm and soles is called as Palmoplantar Psoriasis. The exact cause of it is unknown. It has predominantly hyperkeratotic plaques, thick scaly skin or an overlapping of both of them. Also called as chronic disease which produces functional disability or significant disfigurement and does substantial impairment of person's life. Topical therapy, light therapy, oral medications are part of conventional treatment which offers only a palliative effect. Besides conventional treatment patient choose Homoeopathy because it's a gentle and safe method of treatment that would appear to have positive effects in treatment of Palmoplantar Psoriasis. Summary: A 48 years old Male presented with dry, rough cracked skin with intense itching and burning on both palms and right sole. As he was tabla teacher his day to day activities were hampered. After proper case taking and Repertorization by Kentian approach, Sulphur 1M was prescribed after considering all general and particular characteristic symptoms. The repertory used was SYNTHESIS REPERTORY 8.1 from the Homoeopathic software RADAR. After 3 doses of Sulphur 1M at the gap of 2 months & at the end of 8 months, Re-epithelialisation was seen with an absence of itching and burning and no cracks in skin. This evidence based case report is an example of a successful Homoeopathic Management in cases of Palmoplantar Psoriasis with Kent's approach as Homoeopathy does not treat the disease but the diseased individual.
Subject(s)
Homeopathy , Psoriasis , Humans , Male , Middle Aged , Psoriasis/therapy , Psoriasis/drug therapy , Homeopathy/methodsABSTRACT
BACKGROUND: There is a lack of research studying patient-generated data on Reddit, one of the world's most popular forums with active users interested in dermatology. Techniques within natural language processing, a field of artificial intelligence, can analyze large amounts of text information and extract insights. OBJECTIVE: To apply natural language processing to Reddit comments about dermatology topics to assess for feasibility and potential for insights and engagement. METHODS: A software pipeline preprocessed Reddit comments from 2005 to 2017 from 7 popular dermatology-related subforums on Reddit, applied latent Dirichlet allocation, and used spectral clustering to establish cohesive themes and the frequency of word representation and grouped terms within these topics. RESULTS: We created a corpus of 176,000 comments and identified trends in patient engagement in spaces such as eczema and acne, among others, with a focus on homeopathic treatments and isotretinoin. LIMITATIONS: Latent Dirichlet allocation is an unsupervised model, meaning there is no ground truth to which the model output can be compared. However, because these forums are anonymous, there seems little incentive for patients to be dishonest. CONCLUSIONS: Reddit data has viability and utility for dermatologic research and engagement with the public, especially for common dermatology topics such as tanning, acne, and psoriasis.
Subject(s)
Dermatology/statistics & numerical data , Natural Language Processing , Patient Outcome Assessment , Social Media/statistics & numerical data , Acne Vulgaris/therapy , Cluster Analysis , Feasibility Studies , Humans , Psoriasis/therapy , Reproducibility of Results , Software , SunbathingABSTRACT
BACKGROUND: Psoriasis is a genetically predisposed autoimmune disease mediated by cytokines released by the activated immune cells. It manifests inflammatory, scaly red or white silvery flaky skin which may be a fluid-filled lesion with soreness and itchiness. The prevalence rate of psoriasis is increasing day by day. Despite having such a high prevalence rate, the treatment of psoriasis is still limited. Hence, there is a need to rethink the various treatment strategies available in the allopathic as well as in the alternative systems of medicine. METHODS: Various bibliographic databases of previously published peer-reviewed research papers were explored and systematic data culminated in terms of various treatment strategies used for the management of psoriasis. The prime focus is given towards modern as well as alternative systems of medicine such as phototherapy, a combination of phototherapy with pharmacotherapy such as Ayurveda, Yoga and naturopathy, Unani, Siddha, and Homeopathy to treat psoriasis. RESULTS: A comprehensive review of 161 papers, including both research and review articles, was carried out to make the article readily understandable. The pathogenesis including inflammatory mediators and type of psoriasis is discussed before the treatment strategies to understand the pathophysiology of the disease. The uniqueness, procedure, advantages, and limitations of conventional, advanced, and traditional systems of medicine to treat psoriasis are discussed in detail. Emphasis has also been given towards marine sources such as fish oil, marine sponges, and algae. CONCLUSION: Although there are many modern and alternative treatment strategies available to treat psoriasis, none of them have been proven to provide complete relief to patients. Moreover, they are associated with certain side effects. In order to overcome them, novel drug delivery systems have been utilized and found effective; however, their stability and safety become the major impediments towards their successful positioning. Traditional and alternative treatment strategies have found to be safe and effective but their use is localized to certain areas. In a nutshell, to achieve successful treatment of psoriasis, there is a need to focus on the development of stable and non-toxic novel drug delivery systems or the promotion of traditional systems to treat psoriasis.
Subject(s)
Medicine, Ayurvedic , Medicine, Unani , Naturopathy , Psoriasis/therapy , Yoga , Animals , Drug Delivery Systems , HumansABSTRACT
Design Prospective multicentre observational study. Objective To evaluate details and effects of homeopathic treatment in patients with psoriasis in usual medical care. Methods Primary care patients were evaluated over 2 years using standardized questionnaires, recording diagnoses and complaints severity, health-related quality of life (QoL), medical history, consultations, all treatments, and use of other health services. Results Forty-five physicians treated 82 adults, 51.2% women, aged 41.6 +/- 12.2 (mean +/- SD) years. Patients had psoriasis for 14.7 +/- 11.9 years; 96.3% had been treated before. Initial case taking took 127 +/- 47 min. The 7.4 +/- 7.4 subsequent consultations (duration: 19.4 +/- 10.5 min) cumulated to 169.0 +/- 138.8 min. Patients received 6.0 +/- 4.9 homeopathic prescriptions. Diagnoses and complaints severity improved markedly with large effect sizes (Cohen's d= 1.02-2.09). In addition, QoL improved (SF-36 physical component score d = 0.26, mental component score d = 0.49), while conventional treatment and health service use were considerably reduced. Conclusions Under classical homeopathic treatment, patients with psoriasis improved in symptoms and QoL.
Subject(s)
Homeopathy , Psoriasis/therapy , Adult , Female , Follow-Up Studies , Humans , Male , Middle Aged , Prospective Studies , Psoriasis/physiopathology , Psoriasis/psychology , Quality of LifeABSTRACT
Psoriasis is a common, chronic, recurrent inflammatory skin disorder whose etiology is still unknown. It is believed that a multiple-gene inheritance is involved and it also involves various factors such as immunity, inflammation, cell proliferation, apoptosis, neural media, etc. Since cytokines are key mediators in inflammation, a number of Chinese medicines (CMs) have been reported to have certain antagonist effects on pro-inflammatory cytokines such as tumor necrosis factor-alpha (TNF-alpha), platelet active factor (PAF) and interleukin-8 (IL-8). Some researches on CMs have made significant breakthroughs in psoriasis by intervening with cytokines. Abnormalities with keratinocyte proliferation and apoptosis are considered to be present in patients with psoriasis and a number of studies show that the mechanism of CMs on psoriasis may be through the inhibition of the keratinocyte proliferation and induction of apoptosis. Other studies also show that the inhibition of fibroblast-secreted cytokines could regulate keratinocyte proliferation and differentiation and reduce the level of Calcitonin gene-related peptide (CGRP) in plasma and in lesions so as to slow down the process of inflammation and proliferation in psoriasis. The most commonly used models for psoriasis are the scaled tails or the vaginal epithelium of mice in China. They were used to observe the histopathological changes after the model mice were treated with CMs with the inhibition on the mitosis of vaginal epithelium or promotion of granular layer in rat tail taken as the indices of clinical efficacy. A variety of signs occur in psoriasis patients with TCM blood-stasis syndrome type and the effect of CMs in activating blood circulation to remove blood stasis on psoriasis suggested that the mechanism of CMs may be partially correlated to hemorrheology and microcirculation. Along with the continuous development of the biosciences, some TCM theories for psoriasis have been confirmed by laboratory studies. However, the exploration into traditional Chinese medicines' biomechanics in psoriasis and the therapeutic mechanism of CMs by integrative medicine still requires further studies.
Subject(s)
Drugs, Chinese Herbal/administration & dosage , Materia Medica/administration & dosage , Medicine, Chinese Traditional/methods , Psoriasis/therapy , Research/trends , Animals , China , Cytokines/physiology , Disease Models, Animal , Drug Combinations , Drugs, Chinese Herbal/chemistry , Fibroblasts/drug effects , Fibroblasts/physiology , Hemorheology , Humans , Keratinocytes/drug effects , Keratinocytes/physiology , Microcirculation/drug effects , Microcirculation/physiology , Neuropeptides/physiology , Psoriasis/etiology , Psoriasis/pathologyABSTRACT
There has been a surge of new data regarding the pathophysiology of skin diseases. We are appreciating the sophisticated interplay among the skin, the immune system, and the environment. More elegant and highly specific medicines have been designed to target certain immune mediators of the adaptive immune system. In parallel fashion, we are learning more about the elegance of the innate immune system and how nutrition as early as the prenatal period can affect the priming of other immune cells. Concerns about the long-term impact of new immune-modulating medicines-especially in the pediatric population-have patients asking their dermatologists for nutritional alternatives to medical therapies. Nutrients and nutritional therapies appear to play a role at different ages for different dermatoses. Probiotics are showing promise as a therapeutic option for patients older than 1 year for atopic dermatitis. Systemic contact allergens appear to be a bigger burden on the adult population with atopic dermatitis. Obesity is a growing concern for both children and adults with psoriasis. Milk and high glycemic foods have a strong impact on the teenage acne population. Vitamins A and D are addressed as piece of the alopecia areata puzzle. Zinc and homeopathy are presented finally as possible treatments to the everlasting wart.
Subject(s)
Acne Vulgaris/etiology , Dermatitis, Atopic/therapy , Diet , Psoriasis/therapy , Vitamin D/therapeutic use , Adolescent , Adult , Age Factors , Alopecia Areata/metabolism , Cardiovascular Diseases/epidemiology , Child , Child, Preschool , Dermatitis, Atopic/blood , Dermatitis, Atopic/etiology , Diet/adverse effects , Dietary Supplements , Female , Fish Oils/therapeutic use , Gastrointestinal Diseases/complications , Humans , Infant , Infant, Newborn , Lactation , Obesity/epidemiology , Prebiotics , Pregnancy , Prenatal Exposure Delayed Effects/etiology , Probiotics , Rosacea/complications , Rosacea/therapy , Symptom Flare Up , Vitamin A/metabolism , Vitamin D/bloodSubject(s)
Complementary Therapies , Homeopathy , Naturopathy , Psoriasis/therapy , Humans , Psoriasis/etiologyABSTRACT
Durante mucho tiempo se creyó que un paciente no podía ser tratado con Homeopatía si es que, al momento de la consulta, se encontraba siguiendo un tratamiento alopático. Los doctores Morrison y Herrick establecen las pautas generales que deben seguirse al respecto y los inconvenientes que aparecen al momento de tratar de remplazar la medicina convencional por la medicina homeópata. Una parte del trabajo rescata la opinión que tienen algunos pacientes acerca de los dos sistemas clínicos terapéuticos, así como las expectativas de la familia (y de la sociedad, por extensión) en torno al método clínico configurado por Samuel Hahnemann.
For a long time it was believed that a patient could not be treated with Homeopathy if, at the time of consultation, was following an allopathic treatment. The doctorsHerrick Morrison established the general guidelines to be followed in this regard and disadvantages that appear when trying to replace the conventional medicine homeopathic medicine. Part of the work rescues the opinion they have some patients on the two treatment clinical systems as well as the expectations of the family (and society by extension) about the clinical method set by Samuel Hahnemann.
Subject(s)
Humans , Allopathic Practices , Homeopathy , Homeopathic Therapeutic Approaches , Acne Vulgaris/therapy , Arthritis, Rheumatoid/therapy , Asthma/therapy , Combined Modality Therapy , Estrogens , Eczema/therapy , Osteoarthritis/therapy , Psoriasis/therapy , SteroidsABSTRACT
Durante mucho tiempo se creyó que un paciente no podía ser tratado con Homeopatía si es que, al momento de la consulta, se encontraba siguiendo un tratamiento alopático. Los doctores Morrison y Herrick establecen las pautas generales que deben seguirse al respecto y los inconvenientes que aparecen al momento de tratar de remplazar la medicina convencional por la medicina homeópata. Una parte del trabajo rescata la opinión que tienen algunos pacientes acerca de los dos sistemas clínicos terapéuticos, así como las expectativas de la familia (y de la sociedad, por extensión) en torno al método clínico configurado por Samuel Hahnemann. (AU)
For a long time it was believed that a patient could not be treated with Homeopathy if, at the time of consultation, was following an allopathic treatment. The doctorsHerrick Morrison established the general guidelines to be followed in this regard and disadvantages that appear when trying to replace the conventional medicine homeopathic medicine. Part of the work rescues the opinion they have some patients on the two treatment clinical systems as well as the expectations of the family (and society by extension) about the clinical method set by Samuel Hahnemann. (AU)
Subject(s)
Humans , Allopathic Practices , Homeopathy , Homeopathic Therapeutic Approaches , Combined Modality Therapy , Acne Vulgaris/therapy , Eczema/therapy , Psoriasis/therapy , Osteoarthritis/therapy , Arthritis, Rheumatoid/therapy , Asthma/therapy , Steroids , EstrogensABSTRACT
BACKGROUND: There is increasing evidence for the extensive use of complementary and alternative medicine (CAM) by patients with psoriasis. Clinical research in the arena of CAM and psoriasis treatment is evolving and includes some randomized controlled trials. OBJECTIVE: To study CAM use among patients with psoriasis attending a dermatology clinic in a major university hospital in northern Israel. Prevalence, reasons for CAM use and its relevance to doctor-patient communication were emphasized. METHODS: Semistructured interviews were conducted with psoriasis patients in a dermatology clinic. Consent was obtained for 78 patients. Post-visit questionnaires were given to 5 physicians. RESULTS: Seventy-eight patients with psoriasis were interviewed and 77 were studied. Sixty-two percent used CAM. Fifty-eight percent of users had seen a CAM practitioner. The study found a trend of CAM use among patients with psoriasis from Arab compared to Jewish descent (p=0.087). CAM users reported on average 2 different CAM modalities. Herbal medicine and nutritional treatments ranked first, followed by homeopathy, traditional Chinese medicine and nutritional supplements. The main reason for CAM use was stated to be to do everything to heal the disease, followed by a quest for improved quality of life. Others mentioned an interest in a less toxic treatment, disappointment with conventional treatment and stress reduction. Well over half of the study participants and their dermatologists did not initiate a discussion about CAM use. The dermatologists' ability to predict CAM use in their patients was relatively low. CONCLUSION: There is growing evidence of extensive CAM use among patients with psoriasis. Most patients use CAM as a complementary treatment, rather than an alternative to conventional treatment. Teaching CAM should be integrated into the dermatology residency curriculum. Dermatologists need to increase their awareness of CAM use by their patients in order to improve therapeutic communication.
Subject(s)
Complementary Therapies/statistics & numerical data , Health Knowledge, Attitudes, Practice , Psoriasis/diagnosis , Psoriasis/therapy , Adult , Aged , Cohort Studies , Evidence-Based Medicine , Female , Humans , Israel , Male , Middle Aged , Patient Satisfaction , Physician-Patient Relations , Prognosis , Severity of Illness Index , Surveys and Questionnaires , Treatment OutcomeABSTRACT
In a questionnaire study at a university hospital in Norway, 227 of 444 patients with atopic dermatitis (51.1%) and 215 of 506 patients with psoriasis (42.5%) reported previous or current use of one or more forms of alternative medicine. Homoeopathy, health food preparations and herbal remedies were used most. Use was related to disease duration, disease severity and--among the atopic dermatitis patients--the inefficacy of therapy prescribed by physicians, as judged by the patients. The use of alternative medicine is commonplace and should be of concern to dermatologists.
Subject(s)
Complementary Therapies , Dermatitis, Atopic/therapy , Psoriasis/therapy , Adolescent , Adult , Child , Child, Preschool , Dermatitis, Atopic/diet therapy , Female , Homeopathy , Humans , Infant , Male , Middle Aged , Norway , Plants, Medicinal , Psoriasis/diet therapy , Surveys and QuestionnairesABSTRACT
In a questionnaire study, 227 patients with atopic dermatitis and 215 with psoriasis, who had used alternative medicine, were asked to state their main reason for trying alternative medicine. The answers indicated that the absence of satisfactory effect of physician-provided therapy was the most decisive factor. Their main information sources on alternative therapies were persons without skin disease, and the mass media. The majority reported no improvement, or even aggravation of their skin disease, as a result of alternative treatments (except for diet changes). These findings emphasize the need for documentation of effect of alternative medicine, as well as for further research and education efforts in order to improve therapy for atopic dermatitis and psoriasis.
Subject(s)
Complementary Therapies , Dermatitis, Atopic/therapy , Patients/psychology , Psoriasis/therapy , Complementary Therapies/statistics & numerical data , Consumer Behavior , Dermatitis, Atopic/diet therapy , Homeopathy , Humans , Mass Media , Norway , Plants, Medicinal , Psoriasis/diet therapy , Retrospective Studies , Surveys and QuestionnairesABSTRACT
Le psoriasis est une pathologie chronique frequente touchant de 3 a 15 percent de la population generale en fonction des statistiques. Il debute dans l'enfance dans un tiers des cas, 15 parcent avant 10 ans. C'est une affection familiale - comme en temoigne la presence du "trait" psoriasique chez les ascendants ou les collateraux-, en liaison avec certains antigenes du systeme HLA (HLA-B17 en particulier). Le psoriasis de l'enfant est a predominance masculine (sex-ratio=2/1).(AU)
Subject(s)
Case Reports , Humans , Male , Child, Preschool , Child , Psoriasis/therapy , Homeopathic TherapeuticsABSTRACT
Paciente de 70 anos, hipertensa, hipotiroidea, portadore de anemia megaloblastica, que consulta por psoriasis que cubre toda su superficie corporal (erupcion descamante y pruriginosa) en la que se prescribe... (AU)
Subject(s)
Case Reports , Humans , Female , Adult , Aged , Healing Parameters , Psoriasis/therapy , /therapeutic useABSTRACT
Primer nosode, exprimentado por Samuel Hahnemann, aparece en la revista "Archivos" de Johan Ernest Staph, en 1833 (primer discípulo de Hahnemann que conviene recordar, pues fue su discípulo dilecto con que el mantuvo una amistad que solo la muerte pudo separar), y que experimento 7 medicamentos: (Camph, Cham, China, Nux V, Op, Puls y Rhus Tox). En un medicamento que, en la práctica reúne las indicaciones de los nosodes, incluyendo el de constitucional, con lo que su aplicación abarca múltiples características. Algo similar a lo que ocurre con las Tuberculinas, Medorrhinum, etc. Presentaré el resumen de algunos casos clínicos, de evolución marcadamente favorable, donde se pueden apreciar distintas modalidades de Psorinum, que no precisamente obedece en todos los casos al miasma psórico. Su inclusión definitiva fué durante mucho tiempo postergada por las acaloradas discusiones que suscitó entre los homeópatas y cuya reticencia a ser usado como nosode continúa hasta nuestros días. Es decir "usado como nosode", significa que su acción se ejercerá siempre sobre la fuerza vital, pues de otra manera no actuaría. Si un nosode "usado como nosode" moviliza al paciente de acuerdo a los principios de curación, aunque esté cubriendo pocos síntomas, es justo pensar que, si se efectúan o amplían las patogenesias, aparecerían otros síntomas acordes con el paciente. Hahnemann insistía en usarlo como medicamento con patogenesia y no como nosode
Subject(s)
Humans , Male , Female , Pregnancy , Infant , Adult , Middle Aged , Psorinum , Psoriasis/therapy , Materia MedicaABSTRACT
Patients on allopathic drugs at the time they present for homeopathic treatment can present unique challenges to the practitioner. Dr. Morrison and Nancy Herrick, PA discuss these challenges in detail and offer protocols for managing such cases