Pesquisa | Biblioteca Virtual em Saúde

1.

Disrupted hypothalamic CRH neuron responsiveness contributes to diet-induced obesity.

Zhu, Canjun; Xu, Yuanzhong; Jiang, Zhiying; Tian, Jin Bin; Cassidy, Ryan M; Cai, Zhao-Lin; Shu, Gang; Xu, Yong; Xue, Mingshan; Arenkiel, Benjamin R; Jiang, Qingyan; Tong, Qingchun.

EMBO Rep ; 21(7): e49210, 2020 07 03.

Artigo em Inglês | MEDLINE | ID: mdl-32462726

2.

A cholinergic basal forebrain feeding circuit modulates appetite suppression.

Herman, Alexander M; Ortiz-Guzman, Joshua; Kochukov, Mikhail; Herman, Isabella; Quast, Kathleen B; Patel, Jay M; Tepe, Burak; Carlson, Jeffrey C; Ung, Kevin; Selever, Jennifer; Tong, Qingchun; Arenkiel, Benjamin R.

Nature ; 538(7624): 253-256, 2016 Oct 13.

Artigo em Inglês | MEDLINE | ID: mdl-27698417

3.

Hypothalamic Non-AgRP, Non-POMC GABAergic Neurons Are Required for Postweaning Feeding and NPY Hyperphagia.

Kim, Eun Ran; Wu, Zhaofei; Sun, Hao; Xu, Yuanzhong; Mangieri, Leandra R; Xu, Yong; Tong, Qingchun.

J Neurosci ; 35(29): 10440-50, 2015 Jul 22.

Artigo em Inglês | MEDLINE | ID: mdl-26203139

4.

Anoctamin 4 channel currents activate glucose-inhibited neurons in the mouse ventromedial hypothalamus during hypoglycemia.

Tu, Longlong; Bean, Jonathan C; He, Yang; Liu, Hailan; Yu, Meng; Liu, Hesong; Zhang, Nan; Yin, Na; Han, Junying; Scarcelli, Nikolas A; Conde, Kristine M; Wang, Mengjie; Li, Yongxiang; Feng, Bing; Gao, Peiyu; Cai, Zhao-Lin; Fukuda, Makoto; Xue, Mingshan; Tong, Qingchun; Yang, Yongjie; Liao, Lan; Xu, Jianming; Wang, Chunmei; He, Yanlin; Xu, Yong.

J Clin Invest ; 133(14)2023 07 17.

Artigo em Inglês | MEDLINE | ID: mdl-37261917

5.

Synaptic glutamate release by ventromedial hypothalamic neurons is part of the neurocircuitry that prevents hypoglycemia.

Tong, Qingchun; Ye, ChianPing; McCrimmon, Rory J; Dhillon, Harveen; Choi, Brian; Kramer, Melissa D; Yu, Jia; Yang, Zongfang; Christiansen, Lauryn M; Lee, Charlotte E; Choi, Cheol Soo; Zigman, Jeffrey M; Shulman, Gerald I; Sherwin, Robert S; Elmquist, Joel K; Lowell, Bradford B.

Cell Metab ; 5(5): 383-93, 2007 May.

Artigo em Inglês | MEDLINE | ID: mdl-17488640

6.

The hypothalamus for whole-body physiology: from metabolism to aging.

Liu, Tiemin; Xu, Yong; Yi, Chun-Xia; Tong, Qingchun; Cai, Dongsheng.

Protein Cell ; 13(6): 394-421, 2022 06.

Artigo em Inglês | MEDLINE | ID: mdl-33826123

7.

Activation of basal forebrain-to-lateral habenula circuitry drives reflexive aversion and suppresses feeding behavior.

Swanson, Jessica L; Ortiz-Guzman, Joshua; Srivastava, Snigdha; Chin, Pey-Shyuan; Dooling, Sean W; Hanson Moss, Elizabeth; Kochukov, Mikhail Y; Hunt, Patrick J; Patel, Jay M; Pekarek, Brandon T; Tong, Qingchun; Arenkiel, Benjamin R.

Sci Rep ; 12(1): 22044, 2022 12 21.

Artigo em Inglês | MEDLINE | ID: mdl-36543829

8.

Centrally circulating α-klotho inversely correlates with human obesity and modulates arcuate cell populations in mice.

Landry, Taylor; Li, Peixin; Shookster, Daniel; Jiang, Zhiying; Li, Hongli; Laing, Brenton Thomas; Bunner, Wyatt; Langton, Theodore; Tong, Qingchun; Huang, Hu.

Mol Metab ; 44: 101136, 2021 02.

Artigo em Inglês | MEDLINE | ID: mdl-33301986

9.

Hypothalamic steroid receptor coactivator-2 regulates adaptations to fasting and overnutrition.

Yang, Yongjie; He, Yanlin; Liu, Hailan; Zhou, Wenjun; Wang, Chunmei; Xu, Pingwen; Cai, Xing; Liu, Hesong; Yu, Kaifan; Pei, Zhou; Hyseni, Ilirjana; Fukuda, Makoto; Tong, Qingchun; Xu, Jianming; Sun, Zheng; O'Malley, Bert W; Xu, Yong.

Cell Rep ; 37(10): 110075, 2021 12 07.

Artigo em Inglês | MEDLINE | ID: mdl-34879284

10.

Loss of function of NCOR1 and NCOR2 impairs memory through a novel GABAergic hypothalamus-CA3 projection.

Zhou, Wenjun; He, Yanlin; Rehman, Atteeq U; Kong, Yan; Hong, Sungguan; Ding, Guolian; Yalamanchili, Hari Krishna; Wan, Ying-Wooi; Paul, Basil; Wang, Chuhan; Gong, Yingyun; Zhou, Wenxian; Liu, Hao; Dean, John; Scalais, Emmanuel; O'Driscoll, Mary; Morton, Jenny E V; Hou, Xinguo; Wu, Qi; Tong, Qingchun; Liu, Zhandong; Liu, Pengfei; Xu, Yong; Sun, Zheng.

Nat Neurosci ; 22(2): 205-217, 2019 02.

Artigo em Inglês | MEDLINE | ID: mdl-30664766

11.

Steroid receptor coactivator-1 modulates the function of Pomc neurons and energy homeostasis.

Yang, Yongjie; van der Klaauw, Agatha A; Zhu, Liangru; Cacciottolo, Tessa M; He, Yanlin; Stadler, Lukas K J; Wang, Chunmei; Xu, Pingwen; Saito, Kenji; Hinton, Antentor; Yan, Xiaofeng; Keogh, Julia M; Henning, Elana; Banton, Matthew C; Hendricks, Audrey E; Bochukova, Elena G; Mistry, Vanisha; Lawler, Katherine L; Liao, Lan; Xu, Jianming; O'Rahilly, Stephen; Tong, Qingchun; O'Malley, Bert W; Farooqi, I Sadaf; Xu, Yong.

Nat Commun ; 10(1): 1718, 2019 04 12.

Artigo em Inglês | MEDLINE | ID: mdl-30979869

12.

TAp63 contributes to sexual dimorphism in POMC neuron functions and energy homeostasis.

Wang, Chunmei; He, Yanlin; Xu, Pingwen; Yang, Yongjie; Saito, Kenji; Xia, Yan; Yan, Xiaofeng; Hinton, Antentor; Yan, Chunling; Ding, Hongfang; Yu, Likai; Shu, Gang; Gupta, Rajat; Wu, Qi; Tong, Qingchun; Lagor, William R; Flores, Elsa R; Xu, Yong.

Nat Commun ; 9(1): 1544, 2018 04 18.

Artigo em Inglês | MEDLINE | ID: mdl-29670083

13.

Expanding neurotransmitters in the hypothalamic neurocircuitry for energy balance regulation.

Xu, Yuanzhong; Tong, Qingchun.

Protein Cell ; 2(10): 800-13, 2011 Oct.

Artigo em Inglês | MEDLINE | ID: mdl-22058035

14.

Glucose stimulation of hypothalamic MCH neurons involves K(ATP) channels, is modulated by UCP2, and regulates peripheral glucose homeostasis.

Kong, Dong; Vong, Linh; Parton, Laura E; Ye, Chianping; Tong, Qingchun; Hu, Xiaoxia; Choi, Brian; Brüning, Jens C; Lowell, Bradford B.

Cell Metab ; 12(5): 545-52, 2010 Nov 03.

Artigo em Inglês | MEDLINE | ID: mdl-21035764

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