RESUMO
AIM OF THE STUDY: Botanicals used in Traditional Chinese Medicine (TCM) are a rich source for drug discovery and provide models for multi-component drug development. To facilitate the studies of the actions of TCM drugs and expand their applications, a comprehensive database is urgently required. METHODS: One online resource connects all the relevant data from multiple scientific sources and languages. Drug information from published TCM databases and the official Chinese Pharmacopoeia as well as specialized meta-websites such as Kew's Medicinal Plant Names Service was integrated on a higher level. RESULTS: Our database, SuperTCM, covers the aspects of TCM derived from medicinal plants, encompassing pharmacological recipes up to chemical compounds. It provides the information for 6516 TCM drugs (or "herbs") with 5372 botanical species, 55,772 active ingredients against 543 targets in 254 KEGG pathways associated with 8634 diseases. SuperTCM is freely available at http://tcm.charite.de/supertcm.
Assuntos
Bases de Dados Factuais , Medicamentos de Ervas Chinesas/uso terapêutico , Linguística , Materia Medica/uso terapêutico , Medicina Tradicional Chinesa , Farmacologia em Rede , Integração de Sistemas , Animais , Bases de Dados de Compostos Químicos , Bases de Dados de Produtos Farmacêuticos , Medicamentos de Ervas Chinesas/efeitos adversos , Humanos , Classificação Internacional de Doenças , Materia Medica/efeitos adversos , Farmacopeias como AssuntoRESUMO
Some practical results of computerized data collection are presented. Use was made of the ABIES relational database which supports a medical nomenclature called the READ classification. The Glasgow, Royal London and Bristol Homoeopathic Hospitals have been working together on this project. For practical purposes the main focus in this study has been rheumatoid arthritis. The broader objective, however, is to show the potential of systematic computerized data collection for homoeopathy in general
Assuntos
Humanos , Artrite Reumatoide , Coleta de Dados/estatística & dados numéricos , Classificação Internacional de Doenças , Estatísticas Hospitalares , Inglaterra , Sistemas de Gerenciamento de Base de DadosRESUMO
Se analizaron las historias clínicas de 20 pacientes diagnosticados como parafrenia. Los casos fueron rediagnosticados según el DSM-III-R y el borrador de la CIE-10. Hubo un predominio de mujeres con una edad promedio de 37.3 años. El perfil clínico fue de un apsicosis delirante-alucinatoria de curso crónico sin deterioro de la voluntad y de la actividad pragmática. Los casos analizados se distribuyeron en varias categorías de la CIE-10 y delDSM-III-R; hubo casos que no pudieron ser diagnosticados según el DSM-III-R. Se discute la utilidad de mantener la independencia nosológica de la parafrenia