RESUMO
BACKGROUND: The common cold is one of the most frequently occurring illnesses worldwide. The aim of this study was to determine which OTC anti-common cold medications were most often recommended by pharmacists and if the COVID-19 pandemic affected such recommendations. METHODS: Non-interventional, observational research trial using a self-developed questionnaire to collect data on pharmacists' recommendations for anti-common cold OTC treatment. The data were collected during the COVID-19 pandemic (December 2021-February 2022) in four large community network pharmacies in Lodz (Poland) and then compared with an analogue period of time before the pandemic (December 2019-February 2020). RESULTS: During COVID-19 pandemic there was a significant (p < 0.05) reduction in paracetamol, acetylsalicylic acid, metamizole magnesium, inosines, alpha-mimetics, mucolytics, homeopathics, and sore throat products and an increase in other tablets/capsules and add-on product recommendations. There was a significant relationship (p < 0.05, OR > 1) between the recommended frequency of paracetamol, inosines, sore throat products (each symptom), metamizole magnesium (headache, fever), acetylsalicylic acid (headache, fever, fatigue), NSAIDs, alpha-mimetics (headache, rhinorrhea), pseudoephedrine (rhinorrhea), homeopathics (headache), herbal products (fatigue), antihistamines (rhinorrhea, cough), and mucolytics (headache, fever, cough). CONCLUSIONS: Favorable prices (before COVID-19 pandemic) and reports on common NSAIDs side effects (beginning of the pandemic) led to high sale of paracetamol. Increased awareness of clinical effectiveness of some medications or their reduced availability influenced their limited recommendations.
Assuntos
COVID-19 , Resfriado Comum , Faringite , Humanos , Acetaminofen/uso terapêutico , Anti-Inflamatórios não Esteroides/uso terapêutico , Aspirina/uso terapêutico , Resfriado Comum/tratamento farmacológico , Resfriado Comum/induzido quimicamente , Tosse , Expectorantes/uso terapêutico , Cefaleia/induzido quimicamente , Cefaleia/tratamento farmacológico , Medicamentos sem Prescrição/uso terapêutico , Pandemias , Farmacêuticos , Faringite/induzido quimicamente , Faringite/tratamento farmacológico , RinorreiaRESUMO
BACKGROUND: The aim of this study was to assess the effectiveness of homeopathy compared to conventional treatment in acute respiratory and ear complaints in a primary care setting. METHODS: The study was designed as an international, multi-centre, comparative cohort study of non-randomised design. Patients, presenting themselves with at least one chief complaint: acute (< or = 7 days) runny nose, sore throat, ear pain, sinus pain or cough, were recruited at 57 primary care practices in Austria (8), Germany (8), the Netherlands (7), Russia (6), Spain (6), Ukraine (4), United Kingdom (10) and the USA (8) and given either homeopathic or conventional treatment. Therapy outcome was measured by using the response rate, defined as the proportion of patients experiencing 'complete recovery' or 'major improvement' in each treatment group. The primary outcome criterion was the response rate after 14 days of therapy. RESULTS: Data of 1,577 patients were evaluated in the full analysis set of which 857 received homeopathic (H) and 720 conventional (C) treatment. The majority of patients in both groups reported their outcome after 14 days of treatment as complete recovery or major improvement (H: 86.9%; C: 86.0%; p = 0.0003 for non-inferiority testing). In the per-protocol set (H: 576 and C: 540 patients) similar results were obtained (H: 87.7%; C: 86.9%; p = 0.0019). Further subgroup analysis of the full analysis set showed no differences of response rates after 14 days in children (H: 88.5%; C: 84.5%) and adults (H: 85.6%; C: 86.6%). The unadjusted odds ratio (OR) of the primary outcome criterion was 1.40 (0.89-2.22) in children and 0.92 (0.63-1.34) in adults. Adjustments for demographic differences at baseline did not significantly alter the OR. The response rates after 7 and 28 days also showed no significant differences between both treatment groups. However, onset of improvement within the first 7 days after treatment was significantly faster upon homeopathic treatment both in children (p = 0.0488) and adults (p = 0.0001). Adverse drug reactions occurred more frequently in adults of the conventional group than in the homeopathic group (C: 7.6%; H: 3.1%, p = 0.0032), whereas in children the occurrence of adverse drug reactions was not significantly different (H: 2.0%; C: 2.4%, p = 0.7838). CONCLUSION: In primary care, homeopathic treatment for acute respiratory and ear complaints was not inferior to conventional treatment.
Assuntos
Homeopatia/métodos , Otite/terapia , Atenção Primária à Saúde/métodos , Infecções Respiratórias/terapia , Adulto , Analgésicos/uso terapêutico , Antibacterianos/uso terapêutico , Criança , Estudos de Coortes , Tosse/etiologia , Tosse/terapia , Dor de Orelha/etiologia , Dor de Orelha/terapia , Feminino , Humanos , Masculino , Otite/complicações , Avaliação de Processos e Resultados em Cuidados de Saúde , Satisfação do Paciente , Faringite/etiologia , Faringite/terapia , Infecções Respiratórias/complicações , Rinite/etiologia , Rinite/terapia , Resultado do TratamentoRESUMO
We present 2 cases of severe postoperative sore throat, hoarseness, aphonia, and dysphagia, after a laryngeal mask insertion, who were treated successfully with the homeopathic remedy Arnica montana. Three doses of Arnica montana 200CH were given to the patients over 36 hours. Although the symptoms were very intense, the remedy was very effective and cleared most of the symptoms in 48 hours.
Assuntos
Arnica , Homeopatia , Faringite/tratamento farmacológico , Complicações Pós-Operatórias/tratamento farmacológico , Adulto , Idoso , Feminino , Humanos , MasculinoRESUMO
OBJECTIVE: To investigate the effectiveness and safety of the homeopathic product SilAtro-5-90 in recurrent tonsillitis. METHODS: In this international, pragmatic, controlled clinical trial, 256 patients (6-60 years) with moderate recurrent tonsillitis were randomized to receive either SilAtro-5-90 in addition to standard symptomatic treatment, or to receive standard treatment only. The primary outcome was the mean time period between consecutive acute throat infections (ATI) within 1 year (analyzed via repeated events analysis). RESULTS: During the evaluation year, the risk of getting an ATI was significantly lower (hazard ratio: 0.45, proportional means model, p = 0.0002, ITT) with SilAtro-5-90 compared to control. Tonsillitis-specific symptoms were significantly reduced (p < 0.0001, ITT) and the need of antibiotics to treat acute throat infections (p = 0.0008; ITT) decreased. 3 non-serious adverse drug reactions were reported for SilAtro-5-90. CONCLUSIONS: An integrative treatment approach where SilAtro-5-90 is given alongside mainstream symptomatic treatment may bring therapeutic benefit to patients suffering from recurrent tonsillitis. TRIAL REGISTRATION: ISRCTN registry: Registration number ISRCTN19016626, registered 23 January 2013.
Assuntos
Homeopatia , Materia Medica/uso terapêutico , Tonsilite/tratamento farmacológico , Adolescente , Adulto , Antibacterianos/uso terapêutico , Criança , Comunicação , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Faringite , Recidiva , Resultado do Tratamento , Adulto JovemRESUMO
This survey investigated the management of pediatric tonsillopharyngitis, with a focus on natural remedies. 138 pediatricians, general practitioners and ear-nose-throat (ENT) specialists in 7 countries were surveyed by a dedicated questionnaire. A rapid strept test (RST) to diagnose acute tonsillopharyngitis was routinely used by 56/138 participants (41%). The use of RST allowed 200 diagnosis/year compared with 125 diagnosis/year for clinicians who did not use this tool. Homeopathy remedies were prescribed as a supportive therapy by 62% of participants (85/138). Among different homeopathic remedies, SilAtro-5-90 was the most frequently prescribed (53/138, 38%). In the chronic setting, homeopathy was suggested as a supportive therapy by 82/138 participants (59%), phytotherapy by 39 (28%) and vitamins/nutritional supplementation by 51 (37%). The management of tonsillopharyngitis in pediatric patients still remains empiric. Natural remedies, and homeopathy in particular, are used in the management of URTIs. An integrative approach to these infections may help reduce excessive antibiotic prescription.
Assuntos
Terapias Complementares/estatística & dados numéricos , Medicina Integrativa/estatística & dados numéricos , Faringite/terapia , Padrões de Prática Médica/estatística & dados numéricos , Tonsilite/terapia , Europa (Continente) , Humanos , Pediatria , Médicos/estatística & dados numéricos , Inquéritos e QuestionáriosRESUMO
BACKGROUND: Acute viral tonsillitis is an upper respiratory tract infection prevalent in school-aged children. Because this condition is self-limiting, conventional treatment options are usually palliative. Homeopathic remedies are a useful alternative to conventional medications in acute uncomplicated upper respiratory tract infections in children, offering earlier symptom resolution, cost-effectiveness, and fewer adverse effects. This study aimed to determine the efficacy of a homeopathic complex on the symptoms of acute viral tonsillitis in African children in South Africa. METHODS: This was a randomized, double-blind, placebo-controlled, 6-day pilot study. Thirty children, age 6 to 12 years, with acute viral tonsillitis were recruited from a primary school in Gauteng, South Africa. Participants took two tablets of the medication four times daily. The treatment group received lactose tablets medicated with the homeopathic complex (Atropa belladonna D4, Calcarea phosphoricum D4, Hepar sulphuris D4, Kalium bichromat D4, Kalium muriaticum D4, Mercurius protoiodid D10, and Mercurius biniodid D10). The placebo consisted of the unmedicated vehicle only. The Wong-Baker FACES Pain Rating Scale measured pain intensity, and a Symptom Grading Scale assessed changes in tonsillitis signs and symptoms. RESULTS: The treatment group had a statistically significant improvement in the following symptoms compared with the placebo group: pain associated with tonsillitis, pain on swallowing, erythema and inflammation of the pharynx, and tonsil size. CONCLUSION: The homeopathic complex used in this study exhibited significant anti-inflammatory and pain-relieving qualities in children with acute viral tonsillitis. No patients reported any adverse effects. These preliminary findings are promising; however, the sample size was small and therefore a definitive conclusion cannot be reached. A larger, more inclusive research study should be undertaken to verify the findings of this study.
Assuntos
Materia Medica/uso terapêutico , Tonsilite/tratamento farmacológico , Tonsilite/virologia , Viroses/tratamento farmacológico , Criança , Método Duplo-Cego , Feminino , Humanos , Masculino , Medição da Dor , Faringite , Projetos Piloto , África do Sul , Tonsilite/fisiopatologia , Viroses/fisiopatologia , Sinais VitaisRESUMO
BACKGROUND: Pharmacists play an increasing role in advising on treatment for minor illnesses such as influenza-like illness (ILI) or ear, nose, and throat (ENT) disorders. However, the profile of patients consulting pharmacists with these illnesses, the types of over-the-counter (OTC) medicines recommended by pharmacists, and the effectiveness of these treatments have not been studied. OBJECTIVES: To describe the sociodemographic and clinical characteristics of patients recommended allopathic and/or homeopathic medicines for ILI or ENT disorders by pharmacists in France and to investigate the effectiveness of these treatments. METHODS: A prospective, observational, multicenter study was carried out in randomly selected pharmacies across the 8 IDREM medical regions of France. Pharmacies that agreed to participate recruited male or female patients who responded to the following inclusion criteria: age ≥ 12 years presenting with the first symptoms of an ILI or ENT disorder that were present for less than 36 hours prior to the pharmacy visit. All medicines recorded in the study were recommended by the pharmacists. The following data were recorded at inclusion and after 3 days of treatment: the intensity of 13 symptoms, global symptom score, and disease impact on daily activities and sleep. Two groups of patients were compared: those recommended allopathic medicine only (AT group) and those recommended homeopathic medicine with or without allopathic medicine (HAT group). The number and severity of symptoms, change in global symptom score, and disease impact on daily activities and sleep were compared in the 2 treatment groups after 3 days of treatment. Independent predictors of recommendations for homeopathic medicine were identified by multi-factorial logistic regression analysis. RESULTS: A total of 242 pharmacies out of 4,809 (5.0%) contacted agreed to participate in the study, and 133 (2.8%) included at least 1 patient; 573 patients were analyzed (mean age: 42.5 ± 16.2 years; 61.9% female). Of these, 428 received allopathic medicines only (74.7%; AT group), and 145 (25.3%) received homeopathic medicines (HAT group) alone (9/145, 1.6%) or associated with allopathy (136/145, 23.7%). At inclusion, HAT patients were significantly younger (39.6 ± 14.8 vs. 43.4 ± 16.1 years; P less than 0.05), had a higher mean number of symptoms (5.2 ± 2.5 vs. 4.4 ± 2.5; P less than 0.01), and more severe symptoms (mean global symptom score: 24.3 ± 5.5 vs. 22.3 ± 5.8; P = 0.0019) than AT patients. After 3 days, the improvement in symptoms and disease impact on daily activities and sleep was comparable in both groups of patients. CONCLUSIONS: Patients recommended homeopathic medicine by pharmacists were younger and had more severe symptoms than those recommended allopathic medicine. After 3 days of treatment, clinical improvement was comparable in both treatment groups. Pharmacists have an important role to play in the effective management of ILI and ENT disorders.
Assuntos
Resfriado Comum/tratamento farmacológico , Tosse/tratamento farmacológico , Homeopatia/métodos , Medicamentos sem Prescrição/uso terapêutico , Faringite/tratamento farmacológico , Adolescente , Adulto , Idoso , Idoso de 80 Anos ou mais , Criança , Gerenciamento Clínico , Feminino , Homeopatia/normas , Humanos , Masculino , Pessoa de Meia-Idade , Pacientes Ambulatoriais , Farmacêuticos , Estudos Prospectivos , Adulto JovemAssuntos
Antibacterianos/uso terapêutico , Anti-Inflamatórios não Esteroides/administração & dosagem , Medicina Tradicional , Faringite/terapia , Administração Oral , Homeopatia , Humanos , Faringite/etiologia , Fitoterapia , Infecções Estreptocócicas/diagnóstico , Infecções Estreptocócicas/terapia , Tonsilite/diagnóstico , Tonsilite/terapia , Resultado do TratamentoRESUMO
OBJECTIVES: A pharmacoeconomic study to compare, in terms of: medical effectiveness, quality of life and costs two treatment strategies ('homeopathic strategy' vs 'antibiotic strategy') used in routine medical practice by allopathic and homeopathic GPs in the treatment of recurrent acute rhinopharyngitis in 18-month to 4-year-old children. METHODS: Statistical analysis of data obtained from a population of 499 patients included in a previous 6-month prospective, pragmatic study. The patients were regrouped according to type of drug prescribed. Medical effectiveness was assessed in terms of (i) episodes of acute rhinopharyngitis, (ii) complications, (iii) adverse effects. Quality of life was assessed using the Par-Ent-Qol scale. Direct medical costs (medical consultations, drug prescriptions, prescriptions for further tests) and indirect medical costs (sick-leave) were evaluated from three viewpoints (society, patient, Social Security) using public prices and French Social Security tariffs. RESULTS: The 'homeopathic strategy' yielded significantly better results than the 'antibiotic strategy' in terms of medical effectiveness (number of episodes of rhinopharyngitis: 2.71 vs 3.97, P<0.001; number of complications: 1.25 vs 1.95, P<0.001), and quality of life (global score: 21.38 vs 30.43, P<0.001), with lower direct medical costs covered by Social Security (88 Euros vs 99 Euros, P<0.05) and significantly less sick-leave (9.5% of parents vs 31.6% of parents, P<0.001). CONCLUSIONS: Homeopathy may be a cost-effective alternative to antibiotics in the treatment of recurrent infantile rhinopharyngitis.
Assuntos
Antibacterianos/economia , Homeopatia/economia , Homeopatia/métodos , Faringite/economia , Qualidade de Vida , Rinite/economia , Doença Aguda , Antibacterianos/uso terapêutico , Viés , Criança , Proteção da Criança , Pré-Escolar , Efeitos Psicossociais da Doença , Análise Custo-Benefício , Humanos , Lactente , Faringite/tratamento farmacológico , Rinite/tratamento farmacológicoRESUMO
This study evaluates the antibiotic-prescribing practices of physicians as well as other related issues in the context of viral pharyngitis. In a telephone interview, 535 physicians practising in southeastern France were submitted a clinical case description of an episode of acute pharyngitis in a 2-year-old child. Questions concerned antibiotic treatment and physicians' reasons for their treatment decision. The viral origin of the pharyngitis was more likely to be suspected by paediatricians than by general practitioners (92% vs. 78%, P<0.01); 57% of allopaths (compared with 26% of homeopaths/acupuncturists and 14% of paediatricians, P<0.001) declared they would prescribe an antibiotic in this situation (amoxicillin only in 42% of cases). This difference between allopaths and other physicians was still significant after controlling for knowledge regarding antibiotic therapy. In order to limit the risk of emerging resistant bacteria, it is urgent that training be upgraded for physicians, especially for allopaths.
Assuntos
Antibacterianos/uso terapêutico , Faringite/tratamento farmacológico , Viroses/tratamento farmacológico , Pré-Escolar , Prescrições de Medicamentos , Uso de Medicamentos , França , Humanos , Pediatria , Faringite/virologia , Médicos de Família , Padrões de Prática Médica , Inquéritos e QuestionáriosRESUMO
A randomised double-blind trial was conducted to study the use of two commonly used premedication regimens and the subsequent incidence of sore throat. Fifty adult patients who underwent routine surgery were anaesthetised in a standard fashion after premedication with papaveretum and scopolamine or temazepam, and interviewed after operation to assess the presence of sore throat. A significantly higher incidence of sore throat was associated with the use of papaveretum and scopolamine.
Assuntos
Faringite/induzido quimicamente , Complicações Pós-Operatórias/etiologia , Medicação Pré-Anestésica/efeitos adversos , Adulto , Método Duplo-Cego , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Ópio/efeitos adversos , Ensaios Clínicos Controlados Aleatórios como Assunto , Escopolamina/efeitos adversos , Temazepam/efeitos adversosAssuntos
Antibacterianos/economia , Efeitos Psicossociais da Doença , Homeopatia/economia , Faringite/economia , Rinite/economia , Antibacterianos/uso terapêutico , Viés , Criança , Proteção da Criança , Análise Custo-Benefício , Homeopatia/métodos , Humanos , Relações Mãe-Filho , Faringite/tratamento farmacológico , Rinite/tratamento farmacológicoRESUMO
Les rhino-pharyngites recidivantes de l'enfant (R.P.R.) resultent d'une inflammation du rhino-pharynx avec congestion et suppuration localisee au niveau des formations lymphoides, se repetant chaque annee, non seulement en hiver, mais egalement en d'autres saisons, surtout automne et printemps.(AU)
Assuntos
Rinite/terapia , Faringite/terapia , Nasofaringite/terapia , Terapêutica HomeopáticaRESUMO
Tradicionalmente y en virtud de las reglas de la Nosologia Clasica, la rinofaringitis, amigdalitis y otitis agudas se estudian por separado, pero la clinica nos ensena que son manifestaciones ligadas entre si, pudiendo encontrar un conjunto de sintomas caracteristicos que nos van a permitir definir un terreno particular. Todas las afecciones de rinofaringe, en primer lugar, se caracterizan por inflamaciones congestivas que mas tarde pasan a supurativas, estando localizadas en el tejido linfatico situado en la rinofaringe. Por ellas mismas no son afecciones peligrosas, aunque la practica diaria nos permite ver que son recidivantes debiendo tambien tomar en cuenta el factor horas-nino perdidas en la escuela, y las repercusiones familiares que esto trae aparejado. En la primera fase, los sintomas generales dominan el cuadro; es la fase de congestion y tres medicamentos son los caracteristicos: Aconitum napellus, Belladona atropa, Ferrum phosphoricum
Assuntos
Rinite/terapia , Tonsilite/terapia , Otite Média/terapia , Faringite/terapia , Matéria Médica Clínica , Otorrinolaringopatias/terapiaRESUMO
Ares un rappel sur les donnees actulles et la deficition des thi-pharyngites et de leur caractere recidivant, l'auteur aborde le traitement homeopathique pour la periode aigue des manifestations. Le traitement de fond est ensuite etudie avec les remedes diathesiques et constitutionnels. Cinq observations illustrent la prise en charge des enfants, Un tableau de 12 remedes principaux est propose avec leur caracteristiques et leurs indications. (AU)
Assuntos
Rinite , FaringiteRESUMO
A ORL é um dos motivos mais freqüentes das consultas com os homeopatas, e a dor, aguda ou crônica é, na maioria das vezes, a queixa principal dos pacientes. A prática cotidiana do autor faz deste livro uma oportunidade única para que o homeopata renove seus conhecimentos sobre ORL e progrida na eliminação da dor de seus pacientes.
Assuntos
Terapêutica Homeopática , Otolaringologia , Faringite , Estomatite AftosaRESUMO
A ORL é um dos motivos mais freqüentes das consultas com os homeopatas, e a dor, aguda ou crônica é, na maioria das vezes, a queixa principal dos pacientes. A prática cotidiana do autor faz deste livro uma oportunidade única para que o homeopata renove seus conhecimentos sobre ORL e progrida na eliminação da dor de seus pacientes.