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Excess weight causes disorders in locomotor, cardiorespiratory and reproductive systems and increases the incidence of endocrinopathies, as well it can often cause dyslipidemias, leading to atherosclerosis. Aims: Report the evolution of homeopathic treatment in 4 overweight patients, being 2 female dogs and 2 female rabbits with hypertriglyceridemia, analyzing the values in biochemical test. Methodology:Homeopathic treatment was chosen, based on the principle of similitude, using Cholesterinum due to its action to decrease cholesterol and triglyceride levels. Results:The same protocol was made for all of the four patients, included 2 globules of Cholesterinum 30CH direct in its mouth, every 12 hours for 30 days. The first dog attended on 01/09/2019, and presented 328 mg/dL of triglycerides, decreasing this level to 132 mg/dL after just one-monthtreatment. The second dog attended on 04/05/2019, presented higher hypertriglyceridemia with 617 mg/dL that decreased to 259 mg/dL. Likewise, on 02/06/2019, the first rabbit attended, presented 445mg/dL of triglycerides, which were reduced to 337 mg/dL, while the second rabbit, on 06/27/2019, presented 372 mg/dL of triglycerides, decreasing to 274 mg/dL after. Although the values of cholesterol in all patients were in agreement with the reference, the treatment still proved improvements. In the beginning of the treatment, the first dog showed 207 mg/dL of cholesterol and in the end, it reduced to 170 mg/dL, as well with the second dog with 218 mg/dL in the beginning and 200 mg/dL after. Regarding rabbits, the first one presented an initialvalue of 60 mg/dL, which decreased to 52 mg/dL, while the second started with 57 mg/dL and went to 41 mg/dL. Conventionally, Bezafibrate is indicated as a lipid-lowering agent, but it is contraindicated in patients with liver or kidney failure, vesicular diseases,and for pregnant or lactating. Conclusion:Dyslipidemia can be controlled with High dilution. (The exposed information is consented by the tutors)